Original Research

Published on 09 Aug 2024

Dual TTK/PLK1 inhibition has potent anticancer activity in TNBC as monotherapy and in combination

in Cancer Molecular Targets and Therapeutics

Elisa Zanini
Nicole Forster-Gross
Felix Bachmann
Adrian Brüngger
Paul McSheehy
Karine Litherland
Karin Burger
Anna C. Groner
Mila Roceri
Luc Bury

Frontiers in Oncology

doi 10.3389/fonc.2024.1447807

1,147 views

Review

Published on 07 Aug 2024

The mechanism of ITGB4 in tumor migration and invasion

in Cancer Molecular Targets and Therapeutics

Guichen Huang
Minfeng Zhou
Damin Lu
Jinxiao Li
Qian Tang
Chutong Xiong
Fengxia Liang
Rui Chen

Frontiers in Oncology

doi 10.3389/fonc.2024.1421902

1,474 views

Hypothesis and Theory

Published on 06 Aug 2024

Integrating electromagnetic cancer stress with immunotherapy: a therapeutic paradigm

in Cancer Molecular Targets and Therapeutics

Mark M. Fuster

Frontiers in Oncology

doi 10.3389/fonc.2024.1417621

1,549 views

Mini Review

Published on 05 Aug 2024

Epigenetic regulation of NKG2D ligand and the rise of NK cell-based immunotherapy for cancer treatment

in Cancer Molecular Targets and Therapeutics

Raj Kumar
Romi Gupta

Frontiers in Oncology

doi 10.3389/fonc.2024.1456631

1,277 views

Review

Published on 02 Aug 2024

Combined strategies with PARP inhibitors for the treatment of BRCA wide type cancer

in Cancer Molecular Targets and Therapeutics

Yijun Xie
Di Xiao
Duo Li
Mei Peng
Wei Peng
Huaxin Duan
Xiaoping Yang

Frontiers in Oncology

doi 10.3389/fonc.2024.1441222

1,675 views

Review

Published on 01 Aug 2024

The emerging role of osteoclasts in the treatment of bone metastases: rationale and recent clinical evidence

in Cancer Molecular Targets and Therapeutics

Youjun Liu
Huanshi Chen
Tong Chen
Guowen Qiu
Yu Han

Frontiers in Oncology

doi 10.3389/fonc.2024.1445025

969 views

Case Report

Published on 25 Jul 2024

Denosumab combined with chemotherapy followed by anlotinib in the treatment of multiple metastases of malignant peripheral nerve sheath tumor: a case report and literature review

in Cancer Molecular Targets and Therapeutics

Qian Chen
Haocheng Cui
Kai Zheng
Ming Xu
Xiuchun Yu

Frontiers in Oncology

doi 10.3389/fonc.2024.1399021

754 views

Original Research

Published on 25 Jul 2024

Trabectedin may be a valuable treatment option for elderly patients with metastatic soft tissue sarcomas

in Cancer Molecular Targets and Therapeutics

Gianmaria Miolo
Angela Buonadonna
Davide Lombardi
Simona Scalone
Andrea Lauretta
Lara Della Puppa
Giuseppe Corona

Frontiers in Oncology

doi 10.3389/fonc.2024.1437732

771 views

Review

Published on 18 Jul 2024

Preclinical models for the study of pediatric solid tumors: focus on bone sarcomas

in Cancer Molecular Targets and Therapeutics

D. Isabel Petrescu
Jason T. Yustein
Atreyi Dasgupta

Frontiers in Oncology

doi 10.3389/fonc.2024.1388484

1,060 views

Original Research

Published on 18 Jul 2024

Type II mode of JAK2 inhibition and destabilization are potential therapeutic approaches against the ruxolitinib resistance driven myeloproliferative neoplasms

in Cancer Molecular Targets and Therapeutics

Sivahari P. Gorantla
Gerin Prince
Jasmin Osius
Dhurvas Chandrasekaran Dinesh
Vijay Boddu
Justus Duyster
Nikolas von Bubnoff

Frontiers in Oncology

doi 10.3389/fonc.2024.1430833

1,375 views

Original Research

Published on 17 Jul 2024

The landscape of cancer-associated transcript fusions in adult brain tumors: a longitudinal assessment in 140 patients with cerebral gliomas and brain metastases

in Cancer Molecular Targets and Therapeutics

Philippe Metellus
Clara Camilla
Emilie Bialecki
Nathalie Beaufils
Christine Vellutini
Eric Pellegrino
Pascale Tomasini
Manmeet S. Ahluwalia
Alireza Mansouri
Isabelle Nanni

Frontiers in Oncology

doi 10.3389/fonc.2024.1382394

1,557 views

Review

Published on 17 Jul 2024

Investigating underlying molecular mechanisms, signaling pathways, emerging therapeutic approaches in pancreatic cancer

in Cancer Molecular Targets and Therapeutics

Mohd Mustafa
Kashif Abbas
Mudassir Alam
Safia Habib
Zulfareen
Gulam Mustafa Hasan
Sidra Islam
Anas Shamsi
Imtaiyaz Hassan

Frontiers in Oncology

doi 10.3389/fonc.2024.1427802

2,529 views

Review

Published on 12 Jul 2024

Molecular characteristics and immune microenvironment of gastrointestinal stromal tumours: targets for therapeutic strategies

in Cancer Molecular Targets and Therapeutics

Yang Yu
Mengdie Yu
Lijie Luo
Zijing Zhang
Haiping Zeng
Yan Chen
Zeyu Lin
Mengnan Chen
Wei Wang

Frontiers in Oncology

doi 10.3389/fonc.2024.1405727

844 views

Original Research

Published on 12 Jul 2024

Phase Ib and pharmacokinetics study of alpelisib, a PIK3CA inhibitor, and capecitabine in patients with advanced solid tumors

in Cancer Molecular Targets and Therapeutics

Ah Reum Lim
Boyeon Kim
Jwa Hoon Kim
Myung Han Hyun
Kyong Hwa Park
Yeul Hong Kim
Soohyeon Lee

Frontiers in Oncology

doi 10.3389/fonc.2024.1390452

1,244 views

Mini Review

Published on 11 Jul 2024

Unveiling the role of O(6)-methylguanine-DNA methyltransferase in cancer therapy: insights into alkylators, pharmacogenomics, and others

in Cancer Molecular Targets and Therapeutics

Lizhen Chen
Alex Wen

Frontiers in Oncology

doi 10.3389/fonc.2024.1424797

668 views

Original Research

Published on 09 Jul 2024

Enhancing breast cancer treatment: mesoporous dopamine nanoparticles in synergy with chrysin for photothermal therapy

in Cancer Molecular Targets and Therapeutics

Jing Zhu
Heng Zhang
Haomiao Lan
Bing Bi
Xianfeng Peng
Dandan Li
Haili Wang
Ke Zhu
Fuqiang Shao
Minggang Yin

Frontiers in Oncology

doi 10.3389/fonc.2024.1427858

1,214 views

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Articles

Dual TTK/PLK1 inhibition has potent anticancer activity in TNBC as monotherapy and in combination

The mechanism of ITGB4 in tumor migration and invasion

Integrating electromagnetic cancer stress with immunotherapy: a therapeutic paradigm

Epigenetic regulation of NKG2D ligand and the rise of NK cell-based immunotherapy for cancer treatment

Combined strategies with PARP inhibitors for the treatment of BRCA wide type cancer

The emerging role of osteoclasts in the treatment of bone metastases: rationale and recent clinical evidence

Denosumab combined with chemotherapy followed by anlotinib in the treatment of multiple metastases of malignant peripheral nerve sheath tumor: a case report and literature review

Trabectedin may be a valuable treatment option for elderly patients with metastatic soft tissue sarcomas

Preclinical models for the study of pediatric solid tumors: focus on bone sarcomas

Type II mode of JAK2 inhibition and destabilization are potential therapeutic approaches against the ruxolitinib resistance driven myeloproliferative neoplasms

The landscape of cancer-associated transcript fusions in adult brain tumors: a longitudinal assessment in 140 patients with cerebral gliomas and brain metastases

Investigating underlying molecular mechanisms, signaling pathways, emerging therapeutic approaches in pancreatic cancer

Molecular characteristics and immune microenvironment of gastrointestinal stromal tumours: targets for therapeutic strategies

Phase Ib and pharmacokinetics study of alpelisib, a PIK3CA inhibitor, and capecitabine in patients with advanced solid tumors

Unveiling the role of O(6)-methylguanine-DNA methyltransferase in cancer therapy: insights into alkylators, pharmacogenomics, and others

Enhancing breast cancer treatment: mesoporous dopamine nanoparticles in synergy with chrysin for photothermal therapy