Original Research

Published on 12 May 2022

Exosomal Circsafb2 Reshaping Tumor Environment to Promote Renal Cell Carcinoma Progression by Mediating M2 Macrophage Polarization

in Cancer Molecular Targets and Therapeutics

Xin Huang
Jingyu Wang
Jibin Guan
Zhong Zheng
JunFeng Hao
Zitong Sheng
Menghua Wang
Tianhua Xu
Guangying Guo
Li Yao

Frontiers in Oncology

doi 10.3389/fonc.2022.808888

4,561 views
32 citations

Original Research

Published on 12 May 2022

Statins Lower Lipid Synthesis But Promote Secretion of Cholesterol-Enriched Extracellular Vesicles and Particles

in Cancer Molecular Targets and Therapeutics

Yundi Chen
Yongrui Xu
Jing Wang
Peter Prisinzano
Yuhao Yuan
Fake Lu
Mingfeng Zheng
Wenjun Mao
Yuan Wan

Frontiers in Oncology

doi 10.3389/fonc.2022.853063

3,381 views
3 citations

Original Research

Published on 12 May 2022

Development of Novel CD47-Specific ADCs Possessing High Potency Against Non-Small Cell Lung Cancer in vitro and in vivo

in Cancer Molecular Targets and Therapeutics

Zu-Chian Chiang
Shubin Fang
Yang-kun Shen
Dongya Cui
Huanjiao Weng
Dawei Wang
Yuxiang Zhao
Jizhen Lin
Qi Chen

Frontiers in Oncology

doi 10.3389/fonc.2022.857927

3,770 views
5 citations

Review

Published on 12 May 2022

Implications of Three-Dimensional Cell Culture in Cancer Therapeutic Research

in Cancer Molecular Targets and Therapeutics

Kolluri Poornima
Arul Prakash Francis
Muddasarul Hoda
Mohamed Ahmed Eladl
Srividya Subramanian
Vishnu Priya Veeraraghavan
Mohamed El-Sherbiny
Saad Mohamed Asseri
Abdulrahman Bashir Ahmed Hussamuldin
Krishna Mohan Surapaneni

Frontiers in Oncology

doi 10.3389/fonc.2022.891673

6,504 views
25 citations

Brief Research Report

Published on 12 May 2022

Wnt/β-Catenin Inhibition by CWP232291 as a Novel Therapeutic Strategy in Ovarian Cancer

in Cancer Molecular Targets and Therapeutics

Wenyu Wang
Untack Cho
Anna Yoo
Chae-Lim Jung
Boyun Kim
Heeyeon Kim
Juwon Lee
HyunA Jo
Youngjin Han
Myoung-Hyun Song

Frontiers in Oncology

doi 10.3389/fonc.2022.852260

5,469 views
9 citations

Review

Published on 11 May 2022

Megakaryocytes Are Regulators of the Tumor Microenvironment and Malignant Hematopoietic Progenitor Cells in Myelofibrosis

in Cancer Molecular Targets and Therapeutics

Lilian Varricchio
Ronald Hoffman

Frontiers in Oncology

doi 10.3389/fonc.2022.906698

5,609 views
10 citations

Review

Published on 11 May 2022

LKB1: Can We Target an Hidden Target? Focus on NSCLC

in Cancer Molecular Targets and Therapeutics

Gloriana Ndembe
Ilenia Intini
Elisa Perin
Mirko Marabese
Elisa Caiola
Paolo Mendogni
Lorenzo Rosso
Massimo Broggini
Marika Colombo

Frontiers in Oncology

doi 10.3389/fonc.2022.889826

7,907 views
12 citations

Original Research

Published on 11 May 2022

RRM2 Mediates the Anti-Tumor Effect of the Natural Product Pectolinarigenin on Glioblastoma Through Promoting CDK1 Protein Degradation by Increasing Autophagic Flux

in Cancer Molecular Targets and Therapeutics

Haiping Jiang
Dongzhi Zhang
Karpov Denis Aleksandrovich
Junyi Ye
Lixiang Wang
Xiaofeng Chen
Ming Gao
Xinzhuang Wang
Tao Yan
He Yang

Frontiers in Oncology

doi 10.3389/fonc.2022.887294

3,245 views
9 citations

Review

Published on 11 May 2022

Role of the Pro-Inflammatory Tumor Microenvironment in Extracellular Vesicle-Mediated Transfer of Therapy Resistance

in Cancer Molecular Targets and Therapeutics

Layla Simón
Sofía Sanhueza
Belén Gaete-Ramírez
Manuel Varas-Godoy
Andrew F. G. Quest

Frontiers in Oncology

doi 10.3389/fonc.2022.897205

5,742 views
8 citations

Brief Research Report

Published on 10 May 2022

OGG1 Inhibition Triggers Synthetic Lethality and Enhances The Effect of PARP Inhibitor Olaparib in BRCA1-Deficient TNBC Cells

in Cancer Molecular Targets and Therapeutics

Juan Miguel Baquero
Erik Marchena-Perea
Rocío Mirabet
Raúl Torres-Ruiz
Carmen Blanco-Aparicio
Sandra Rodríguez-Perales
Thomas Helleday
Carlos Benítez-Buelga
Javier Benítez
Ana Osorio

Frontiers in Oncology

doi 10.3389/fonc.2022.888810

4,227 views
9 citations

Original Research

Published on 09 May 2022

ST08 Altered NF-κB Pathway in Breast Cancer Cells In Vitro as Revealed by miRNA-mRNA Analysis and Enhanced the Effect of Cisplatin on Tumour Reduction in EAC Mouse Model

in Cancer Molecular Targets and Therapeutics

Snehal Nirgude
Sagar Desai
Raghunandan Mahadeva
Febina Ravindran
Bibha Choudhary

Frontiers in Oncology

doi 10.3389/fonc.2022.835027

3,221 views
11 citations

Review

Published on 09 May 2022

Advances in the Study of CircRNAs in Tumor Drug Resistance

in Cancer Molecular Targets and Therapeutics

Song Wang
Long Qian
Tingting Cao
Li Xu
Yan Jin
Hao Hu
Qingsheng Fu
Qian Li
Ye Wang
Jiawei Wang

Frontiers in Oncology

doi 10.3389/fonc.2022.868363

2,917 views
10 citations

Opinion

Published on 06 May 2022

Insights of Oncofertility in Mexico and Latin America

in Cancer Molecular Targets and Therapeutics

Francisco Jiménez-Trejo
Cristian Arriaga-Canon
Luis A. Herrera
Telma Lisboa-Nascimento
Daniel Diaz

Frontiers in Oncology

doi 10.3389/fonc.2022.811464

1,186 views

Original Research

Published on 04 May 2022

Exosomes Derived From Dendritic Cells Infected With Toxoplasma gondii Show Antitumoral Activity in a Mouse Model of Colorectal Cancer

in Cancer Molecular Targets and Therapeutics

Jinmiao Lu
Nana Wei
Shilan Zhu
Xiaoyu Chen
Haiyan Gong
Rongsheng Mi
Yan Huang
Zhaoguo Chen
Guoqing Li

Frontiers in Oncology

doi 10.3389/fonc.2022.899737

3,324 views
13 citations

Review

Published on 04 May 2022

Recent Advances of Autophagy in Non-Small Cell Lung Cancer: From Basic Mechanisms to Clinical Application

in Cancer Molecular Targets and Therapeutics

Weina Guo
Keye Du
Shanshan Luo
Desheng Hu

Frontiers in Oncology

doi 10.3389/fonc.2022.861959

5,031 views
15 citations

Original Research

Published on 04 May 2022

Berberine and Oligomeric Proanthocyanidins Exhibit Synergistic Efficacy Through Regulation of PI3K-Akt Signaling Pathway in Colorectal Cancer

in Cancer Molecular Targets and Therapeutics

Keisuke Okuno
Rachana Garg
Yate-Ching Yuan
Masanori Tokunaga
Yusuke Kinugasa
Ajay Goel

Frontiers in Oncology

doi 10.3389/fonc.2022.855860

4,254 views
17 citations

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Articles

Exosomal Circsafb2 Reshaping Tumor Environment to Promote Renal Cell Carcinoma Progression by Mediating M2 Macrophage Polarization

Statins Lower Lipid Synthesis But Promote Secretion of Cholesterol-Enriched Extracellular Vesicles and Particles

Development of Novel CD47-Specific ADCs Possessing High Potency Against Non-Small Cell Lung Cancer in vitro and in vivo

Implications of Three-Dimensional Cell Culture in Cancer Therapeutic Research

Wnt/β-Catenin Inhibition by CWP232291 as a Novel Therapeutic Strategy in Ovarian Cancer

Megakaryocytes Are Regulators of the Tumor Microenvironment and Malignant Hematopoietic Progenitor Cells in Myelofibrosis

LKB1: Can We Target an Hidden Target? Focus on NSCLC

RRM2 Mediates the Anti-Tumor Effect of the Natural Product Pectolinarigenin on Glioblastoma Through Promoting CDK1 Protein Degradation by Increasing Autophagic Flux

Role of the Pro-Inflammatory Tumor Microenvironment in Extracellular Vesicle-Mediated Transfer of Therapy Resistance

OGG1 Inhibition Triggers Synthetic Lethality and Enhances The Effect of PARP Inhibitor Olaparib in BRCA1-Deficient TNBC Cells

ST08 Altered NF-κB Pathway in Breast Cancer Cells In Vitro as Revealed by miRNA-mRNA Analysis and Enhanced the Effect of Cisplatin on Tumour Reduction in EAC Mouse Model

Advances in the Study of CircRNAs in Tumor Drug Resistance

Insights of Oncofertility in Mexico and Latin America

Exosomes Derived From Dendritic Cells Infected With Toxoplasma gondii Show Antitumoral Activity in a Mouse Model of Colorectal Cancer

Recent Advances of Autophagy in Non-Small Cell Lung Cancer: From Basic Mechanisms to Clinical Application

Berberine and Oligomeric Proanthocyanidins Exhibit Synergistic Efficacy Through Regulation of PI3K-Akt Signaling Pathway in Colorectal Cancer