Frontiers in Oncology | Cancer Molecular Targets and Therapeutics

Original Research

Accepted on 16 Jan 2025

A Pan-Cancer Analysis of Homeobox (HOX) Family: expression characteristics and latent significance in prognosis and immune microenvironment

in Cancer Molecular Targets and Therapeutics

Yuanhui Wang
Jie Gao
Ziyi Ren
Ziyi Shen
Wei Gu
Qinyi Miao
Xiaomeng Hu
Yan Wu
Wei Liu
Jia Jia

Frontiers in Oncology

doi 10.3389/fonc.2025.1521652

Original Research

Accepted on 16 Jan 2025

Evaluation of patient immunocompetence for immune checkpoint inhibitor therapy using the psoas muscle index: a retrospective cohort study

in Cancer Molecular Targets and Therapeutics

Toshiaki Tsurui
Kazuyuki Hamada
Emiko Mura
Risako Suzuki
Nana Iriguchi
Tomoyuki Ishiguro
Yuya Hirasawa
Ryotaro Ohkuma
Masahiro Shimokawa
Hirotsugu Ariizumi

Frontiers in Oncology

doi 10.3389/fonc.2025.1499650

Mini Review

Accepted on 16 Jan 2025

DNA Methylation and Immune Evasion in Triple-Negative Breast Cancer: Challenges and Therapeutic Opportunities

in Cancer Molecular Targets and Therapeutics

Wen-yu Cai
Xin-Xian Cai
Yi-Ran Fei
Rui Ye
Ding-ming Song
Dan Hu
Wan- Wan Zhang
Ming-Fei Xia
Xiao-Xiao Yang

Frontiers in Oncology

doi 10.3389/fonc.2025.1534055

Original Research

Published on 16 Jan 2025

Implication of fibroblast growth factor 7 in ovarian cancer metastases and patient survival

in Cancer Molecular Targets and Therapeutics

Laura F. Mortan
Brooke A. Meelheim
Justin Garland
Jacqueline A. Bohn
Zitha Redempta Isingizwe
Doris M. Benbrook

Frontiers in Oncology

doi 10.3389/fonc.2024.1524606

245 views

Original Research

Published on 16 Jan 2025

Predicting recurrence of non-muscle invasive bladder urothelial carcinoma: predictive value of the optimal cut-off value of Ki67

in Cancer Molecular Targets and Therapeutics

Rende Peng
Yaoyu Zhang
Mingzhu Jia
Xinping Yi
Xiaoyao Yi
Shadan Li
Jiangchuan Pi
Wenjun Meng

Frontiers in Oncology

doi 10.3389/fonc.2024.1522009

200 views

Review

Accepted on 15 Jan 2025

Advances in Non-Apoptotic Regulated Cell Death: Implications for Malignant Tumor Treatment

in Cancer Molecular Targets and Therapeutics

Yizheng Zhang
Shiqi Yi
Mingyuan Luan

Frontiers in Oncology

doi 10.3389/fonc.2025.1519119

Case Report

Published on 15 Jan 2025

Case report: Selpercatinib in the treatment of RET fusion-positive advanced lung adenocarcinoma: a challenging clinical case

in Cancer Molecular Targets and Therapeutics

Raffaella Pagliaro
Paola Maria Medusa
Fabiana Vitiello
Luigi Aronne
Susan F. M. Campbell
Fabio Perrotta
Andrea Bianco

Frontiers in Oncology

doi 10.3389/fonc.2024.1500449

171 views

Systematic Review

Published on 15 Jan 2025

First-line treatment for advanced or metastatic EGFR mutation-positive non-squamous non-small cell lung cancer: a network meta-analysis

in Cancer Molecular Targets and Therapeutics

Mengyao Zhang
Lan Sun

Frontiers in Oncology

doi 10.3389/fonc.2024.1498518

239 views

Review

Accepted on 14 Jan 2025

The Role of ESRP1 in Solid Tumor Development through the Regulation of CD44 Splicing and EMT Processes

in Cancer Molecular Targets and Therapeutics

Lili Wang
Min Zhang
Lei Ke Zhao
Xiaohan Yuan
Houyu Zhao
Yanting Liu
Yinghua Ji
Ping Lu

Frontiers in Oncology

doi 10.3389/fonc.2025.1451130

Mini Review

Accepted on 14 Jan 2025

Improving CD3 bispecific antibody therapy in solid tumors using combination strategies

in Cancer Molecular Targets and Therapeutics

Katy Lloyd
Jim Middelburg
Vitalijs Ovcinnikovs
Nora Pencheva
Kristel Kemper
Thorbald van Hall

Frontiers in Oncology

doi 10.3389/fonc.2025.1548446

Original Research

Published on 14 Jan 2025

Efficacy and safety of anlotinib as maintenance treatment in extensive-stage small cell lung cancer: a single-armed single center retrospective study

in Cancer Molecular Targets and Therapeutics

Jin Xiong
Lei Xia

Frontiers in Oncology

doi 10.3389/fonc.2024.1462581

197 views

Systematic Review

Accepted on 13 Jan 2025

Exploring the Role of Artificial Intelligence in Chemotherapy Development, Cancer Diagnosis, and Treatment: Present Achievements and Future Outlook

in Cancer Molecular Targets and Therapeutics

Bassam Abdul
Ali Haider Mohammed
Souheil Hallit
Diana Malaeb
Hassan Hosseini

Frontiers in Oncology

doi 10.3389/fonc.2025.1475893

Original Research

Accepted on 13 Jan 2025

Dihydrotanshinone I enhanced BRAF mutant melanoma treatment efficacy by inhibiting the STAT3/SOX2 signaling pathway

in Cancer Molecular Targets and Therapeutics

Xing Luo
Yi Duan
JinWei He
CongGai Huang
Jun Liu
YiFan Liu
MengDei Xu
Qiong Dai
ZhiHui Yang

Frontiers in Oncology

doi 10.3389/fonc.2025.1429018

Case Report

Accepted on 13 Jan 2025

A rare case of vision loss caused by leptomeningeal metastasis of lung adenocarcinoma: a case report and literature review

in Cancer Molecular Targets and Therapeutics

Zhihua LI
Jian Chu
Wennan Shen
Junnan Chen
Yuemei Dong
Manze Zhang
Nan Zhao
Wei Zhao
Haoran Zha
Yalin Han

Frontiers in Oncology

doi 10.3389/fonc.2025.1484383

Review

Accepted on 09 Jan 2025

MicroRNA155 in non-small cell lung cancer: a potential therapeutic target

in Cancer Molecular Targets and Therapeutics

Xiangju Wei
wenhui zhang
xianmin xiong
ze chen

Frontiers in Oncology

doi 10.3389/fonc.2025.1517995

Original Research

Published on 09 Jan 2025

Rational strategies for designing next-generation oncolytic viruses based on transcriptome analysis of tumor cells infected with oncolytic herpes simplex virus-1

in Cancer Molecular Targets and Therapeutics

Naeme Javid
Shahriyar Abdoli
Majid Shahbazi

Frontiers in Oncology

doi 10.3389/fonc.2024.1469511

169 views

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Articles

A Pan-Cancer Analysis of Homeobox (HOX) Family: expression characteristics and latent significance in prognosis and immune microenvironment

Evaluation of patient immunocompetence for immune checkpoint inhibitor therapy using the psoas muscle index: a retrospective cohort study

DNA Methylation and Immune Evasion in Triple-Negative Breast Cancer: Challenges and Therapeutic Opportunities

Implication of fibroblast growth factor 7 in ovarian cancer metastases and patient survival

Predicting recurrence of non-muscle invasive bladder urothelial carcinoma: predictive value of the optimal cut-off value of Ki67

Advances in Non-Apoptotic Regulated Cell Death: Implications for Malignant Tumor Treatment

Case report: Selpercatinib in the treatment of RET fusion-positive advanced lung adenocarcinoma: a challenging clinical case

First-line treatment for advanced or metastatic EGFR mutation-positive non-squamous non-small cell lung cancer: a network meta-analysis

The Role of ESRP1 in Solid Tumor Development through the Regulation of CD44 Splicing and EMT Processes

Improving CD3 bispecific antibody therapy in solid tumors using combination strategies

Efficacy and safety of anlotinib as maintenance treatment in extensive-stage small cell lung cancer: a single-armed single center retrospective study

Exploring the Role of Artificial Intelligence in Chemotherapy Development, Cancer Diagnosis, and Treatment: Present Achievements and Future Outlook

Dihydrotanshinone I enhanced BRAF mutant melanoma treatment efficacy by inhibiting the STAT3/SOX2 signaling pathway

A rare case of vision loss caused by leptomeningeal metastasis of lung adenocarcinoma: a case report and literature review

MicroRNA155 in non-small cell lung cancer: a potential therapeutic target

Rational strategies for designing next-generation oncolytic viruses based on transcriptome analysis of tumor cells infected with oncolytic herpes simplex virus-1