Frontiers in Oncology | Cancer Genetics

Original Research

Accepted on 22 Apr 2025

Integrating Next-Generation Sequencing and Artificial Intelligence for the Identification and Validation of Pathogenic Variants in Colorectal Cancer

in Cancer Genetics

Juliana Rodriguez-Salamanca
mariana Angulo-Aguado
Sarah Orjuela Amarillo
Catalina Duque
Diana Carolina Sierra
Nora Constanza De Jesús Contreras
Carlos Figueroa
Carlos Restrepo
Andrés López-Cortés
Rodrigo Cabrera

Frontiers in Oncology

doi 10.3389/fonc.2025.1568205

Original Research

Accepted on 16 Apr 2025

Revisiting the Molecular Landscape of Rosai-Dorfman Disease: Insights from Whole Exome Sequencing of Saudi Patients

in Cancer Genetics

Sarah Binhassan
Manar Samman
Yazeed Al-Sheikh
Wafaa Alshakweer
Tahani Alhalouly
Najd Alshamlan
Manal Abudawood

Frontiers in Oncology

doi 10.3389/fonc.2025.1556830

120 views

Case Report

Accepted on 15 Apr 2025

Retroperitoneal dedifferentiated solitary fibrous tumor with unexpected Pax-2 expression, mimicking high grade clear cell renal cell carcinoma

in Cancer Genetics

Jia Wei
Chen-chen Yao
Yue-Fen Zou
Yong-Zhong Wei
Qin-He Fan
Qi-Xing Gong

Frontiers in Oncology

doi 10.3389/fonc.2025.1569160

Original Research

Published on 15 Apr 2025

Down-regulation of miR-125b by HPV16 E6 might promote cervical cancer progression through TAZ/TEAD

in Cancer Genetics

Yongli Hou
Lili Zhang
Wenhao Wang
Keyan Cheng
Hui Wang
Yanfei Ji
Xiaoqiang Su
Min Hao

Frontiers in Oncology

doi 10.3389/fonc.2025.1444874

226 views

Original Research

Published on 08 Apr 2025

5hmC-profiles in Puerto Rican Hispanic/Latino men with aggressive prostate cancer

in Cancer Genetics

Manishkumar S. Patel
Mousa Almubarak
Jaime Matta
Carmen Ortiz-Sanchez
Jarline Encarnacion
Gilberto Ruiz-Deya
Julie Dutil
Jasreman Dhillon
Kosj Yamoah
Anders Berglund

Frontiers in Oncology

doi 10.3389/fonc.2025.1541878

458 views

Case Report

Accepted on 04 Apr 2025

Comparative Analysis of Whole Genome Sequencing of Tumor and cfDNA in a Neuroblastoma Patient: A Case Study

in Cancer Genetics

Susanne Fransson
Kleopatra Georgantzi
Anna Djos
Jennie Gaarder
Johanna Svensson
Vimala Anthonydhason
Per Kogner
Tommy Martinsson
Ganesh Umapathy

Frontiers in Oncology

doi 10.3389/fonc.2025.1569520

191 views

Case Report

Published on 04 Apr 2025

Cerebral CIC-NUTM1 rearrangement sarcoma- case report and review of the literature

in Cancer Genetics

Wei Jin
Ke Dong
Fan Yang
Jianning Zhang
Gang Cheng

Frontiers in Oncology

doi 10.3389/fonc.2025.1519335

505 views

Case Report

Published on 04 Apr 2025

Case Report: Myeloid neoplasms with the t(3;12)(q26.2;p13.1)/MECOM-ETV6 translocation: report of two new cases and review of the literature

in Cancer Genetics

Soumya Mikkilineni
Juan Pablo Pineda-Reyes
Lindsay Wilde
Andres Ferber
Zi-Xuan Wang
Stephen Peiper
Guldeep Uppal
Jerald Gong
Jinglan Liu

Frontiers in Oncology

doi 10.3389/fonc.2025.1526044

474 views

Original Research

Accepted on 02 Apr 2025

A Proteotranscriptomic Approach to Dissect the Molecular Landscape of Human Retinoblastoma

in Cancer Genetics

Julian Wolf
Rozina Ida Hajdu
Stefaniya Konstantinova Boneva
Ira Godbole
Lucas Stürzbecher
Claudia Auw-Haedrich
Wolf Lagrèze
Hansjürgen Agostini
Thomas Reinhard
Stefan Tholen

Frontiers in Oncology

doi 10.3389/fonc.2025.1571702

Original Research

Published on 01 Apr 2025

EFTUD2 is a promising diagnostic and prognostic indicator involved in the tumor immune microenvironment and glycolysis of lung adenocarcinoma

in Cancer Genetics

Ankang Yin
Yufan Xu
Xiyang Su
Runan Wang
Zebin Zhang
Yi Chen
Lu Han
Guoxiang Fu
Wei Wang
Juan Wang

Frontiers in Oncology

doi 10.3389/fonc.2025.1499217

782 views

Original Research

Published on 25 Mar 2025

Discovery of a DNA repair-associated radiosensitivity index for predicting radiotherapy efficacy in breast cancer

in Cancer Genetics

Jianguang Lin
Hainan Yang
Rongfu Huang
Tianwen Xu

Frontiers in Oncology

doi 10.3389/fonc.2025.1439516

601 views

Original Research

Published on 06 Mar 2025

Association of the IL-10 and IL-18 polymorphisms with nasopharyngeal carcinoma risk

in Cancer Genetics

Xueru Chen
Ruibin Zhang
Hui Xie
Sha Li
Jincai Guo
Yan Wang

Frontiers in Oncology

doi 10.3389/fonc.2025.1543182

525 views

Original Research

Published on 04 Mar 2025

Multi-omics approach reveals the impact of prognosis model-related genes on the tumor microenvironment in medulloblastoma

in Cancer Genetics

Dongming Han
Xuan Chen
Xin Jin
Jiankang Li
Dongyang Wang
Ziwei Wang

Frontiers in Oncology

doi 10.3389/fonc.2025.1477617

1,253 views

Case Report

Published on 19 Feb 2025

Case report: The smallest 9p21.3 microdeletion involving CDKN2A but not CDKN2B causes multiple plexiform neurofibromas

in Cancer Genetics

Yuanyuan Zhang
Xiang Li
Haiming Gao
Chuang Qiu
Xiaoliang Liu

Frontiers in Oncology

doi 10.3389/fonc.2025.1437093

616 views

Original Research

Published on 18 Feb 2025

Reclassification of variants of uncertain significance by race, ethnicity, and ancestry for patients at risk for breast cancer

in Cancer Genetics

Versha Pleasant
Jordyn Boggan
Blair Richards
Kara J. Milliron
Kristen S. Purrington
Michael Simon
Sofia Merajver

Frontiers in Oncology

doi 10.3389/fonc.2025.1455509

876 views

Review

Published on 14 Feb 2025

The role of telomere and telomerase in cancer and novel therapeutic target: narrative review

in Cancer Genetics

Temesgen Baylie
Mohammed Jemal
Gelagay Baye
Mamaru Getinet
Gashaw Azanaw Amare
Adane Adugna
Desalegn Abebaw
Zigale Hibstu
Bantayehu Addis Tegegne
Endalkachew Gugsa

Frontiers in Oncology

doi 10.3389/fonc.2025.1542930

1,791 views