Original Research

Published on 24 Jun 2021

Evaluation of Neuropathological Features in the SOD1-G93A Low Copy Number Transgenic Mouse Model of Amyotrophic Lateral Sclerosis

in Brain Disease Mechanisms

Agnes Molnar-Kasza
Barbara Hinteregger
Joerg Neddens
Roland Rabl
Stefanie Flunkert
Birgit Hutter-Paier

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2021.681868

7,449 views
4 citations

Perspective

Published on 17 Jun 2021

Synaptic Plasticity and Oscillations in Alzheimer’s Disease: A Complex Picture of a Multifaceted Disease

in Brain Disease Mechanisms

Yuniesky Andrade-Talavera
Antonio Rodríguez-Moreno

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2021.696476

5,734 views
22 citations

Perspective

Published on 15 Jun 2021

Conceptual and Methodological Pitfalls in Experimental Studies: An Overview, and the Case of Alzheimer’s Disease

in Brain Disease Mechanisms

Daniela Puzzo
Fiorenzo Conti

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2021.684977

3,099 views
5 citations

Review

Published on 14 Jun 2021

Axonal Transport and Local Translation of mRNA in Neurodegenerative Diseases

in Brain Disease Mechanisms

Seiichi Nagano
Toshiyuki Araki

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2021.697973

10,962 views
17 citations

Mini Review

Published on 28 May 2021

Astroglial Connexins in Neurodegenerative Diseases

in Brain Disease Mechanisms

Xiaomin Huang
Yixun Su
Nan Wang
Hui Li
Zhigang Li
Guowei Yin
Hui Chen
Jianqin Niu
Chenju Yi

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2021.657514

7,290 views
33 citations

Original Research

Published on 21 May 2021

CircRNA-ceRNA Network Revealing the Potential Regulatory Roles of CircRNA in Alzheimer’s Disease Involved the cGMP-PKG Signal Pathway

in Brain Disease Mechanisms

Yuan Zhang
Lili Qian
Yingying Liu
Ying Liu
Wanpeng Yu
Yanfang Zhao

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2021.665788

9,481 views
35 citations

Brief Research Report

Published on 13 May 2021

Parkin Levels Decrease in Fibroblasts With Progranulin (PGRN) Pathogenic Variants and in a Cellular Model of PGRN Deficiency

in Brain Disease Mechanisms

Katarzyna Gaweda-Walerych
Dawid Walerych
Mariusz Berdyński
Emanuele Buratti
Cezary Zekanowski

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2021.676478

4,602 views
15 citations

Mini Review

Published on 11 May 2021

Microglial Exosomes in Neurodegenerative Disease

in Brain Disease Mechanisms

Min Guo
Yining Hao
Yiwei Feng
Haiqing Li
Yiting Mao
Qiang Dong
Mei Cui

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2021.630808

20,055 views
60 citations

Specialty Grand Challenge

Published on 10 May 2021

Specialty Grand Challenge for Brain Disease Mechanisms

in Brain Disease Mechanisms

Detlev Boison

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2021.689903

2,416 views
1 citation

Original Research

Published on 29 Apr 2021

Evaluation of Zn, Cu, and Se Levels in the North American Autism Spectrum Disorder Population

in Brain Disease Mechanisms

Sunil Q. Mehta
Supriya Behl
Patrick L. Day
Adriana M. Delgado
Nicholas B. Larson
Lindsay R. Stromback
Andrea R. Huebner
Timothy R. DeGrado
Jessica M. Davis
Paul J. Jannetto

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2021.665686

5,007 views
16 citations

Original Research

Published on 30 Mar 2021

Spatiotemporal Correlation of Epileptiform Activity and Gene Expression in vitro

in Brain Disease Mechanisms

Sophie Schlabitz
Laura Monni
Alienor Ragot
Matthias Dipper-Wawra
Julia Onken
Martin Holtkamp
Pawel Fidzinski

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2021.643763

5,067 views
6 citations

Editorial

Published on 22 Mar 2021

Editorial: Dysfunction and Repair of Neural Circuits for Motor Control

in Brain Disease Mechanisms

Andrew Paul Tosolini
George Z. Mentis
John H. Martin

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2021.669824

3,125 views
1 citation

Review

Published on 18 Mar 2021

40 Years of CSF Toxicity Studies in ALS: What Have We Learnt About ALS Pathophysiology?

in Brain Disease Mechanisms

Koy Chong Ng Kee Kwong
Pratap K. Harbham
Bhuvaneish T. Selvaraj
Jenna M. Gregory
Suvankar Pal
Giles E. Hardingham
Siddharthan Chandran
Arpan R. Mehta

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2021.647895

8,277 views
11 citations

Original Research

Published on 18 Mar 2021

Targeted Quantification of Detergent-Insoluble RNA-Binding Proteins in Human Brain Reveals Stage and Disease Specific Co-aggregation in Alzheimer’s Disease

in Brain Disease Mechanisms

Qi Guo
Eric B. Dammer
Maotian Zhou
Sean R. Kundinger
Marla Gearing
James J. Lah
Allan I. Levey
Joshua M. Shulman
Nicholas T. Seyfried

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2021.623659

8,773 views
16 citations

Mini Review

Published on 17 Mar 2021

Involvement of Astrocytes and microRNA Dysregulation in Neurodegenerative Diseases: From Pathogenesis to Therapeutic Potential

in Brain Disease Mechanisms

Yang Bai
Xing Su
Lianhua Piao
Zheng Jin
Rihua Jin

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2021.556215

5,730 views
23 citations

Mini Review

Published on 12 Mar 2021

MicroRNA Dysregulation in Epilepsy: From Pathogenetic Involvement to Diagnostic Biomarker and Therapeutic Agent Development

in Brain Disease Mechanisms

Jialu Wang
Jiuhan Zhao

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2021.650372

12,152 views
41 citations

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Articles

Evaluation of Neuropathological Features in the SOD1-G93A Low Copy Number Transgenic Mouse Model of Amyotrophic Lateral Sclerosis

Synaptic Plasticity and Oscillations in Alzheimer’s Disease: A Complex Picture of a Multifaceted Disease

Conceptual and Methodological Pitfalls in Experimental Studies: An Overview, and the Case of Alzheimer’s Disease

Axonal Transport and Local Translation of mRNA in Neurodegenerative Diseases

Astroglial Connexins in Neurodegenerative Diseases

CircRNA-ceRNA Network Revealing the Potential Regulatory Roles of CircRNA in Alzheimer’s Disease Involved the cGMP-PKG Signal Pathway

Parkin Levels Decrease in Fibroblasts With Progranulin (PGRN) Pathogenic Variants and in a Cellular Model of PGRN Deficiency

Microglial Exosomes in Neurodegenerative Disease

Specialty Grand Challenge for Brain Disease Mechanisms

Evaluation of Zn, Cu, and Se Levels in the North American Autism Spectrum Disorder Population

Spatiotemporal Correlation of Epileptiform Activity and Gene Expression in vitro

Editorial: Dysfunction and Repair of Neural Circuits for Motor Control

40 Years of CSF Toxicity Studies in ALS: What Have We Learnt About ALS Pathophysiology?

Targeted Quantification of Detergent-Insoluble RNA-Binding Proteins in Human Brain Reveals Stage and Disease Specific Co-aggregation in Alzheimer’s Disease

Involvement of Astrocytes and microRNA Dysregulation in Neurodegenerative Diseases: From Pathogenesis to Therapeutic Potential

MicroRNA Dysregulation in Epilepsy: From Pathogenetic Involvement to Diagnostic Biomarker and Therapeutic Agent Development