Original Research

Published on 19 Aug 2021

Application of Trio-Whole Exome Sequencing in Genetic Diagnosis and Therapy in Chinese Children With Epilepsy

in Brain Disease Mechanisms

Tiejia Jiang
Jia Gao
Lihua Jiang
Lu Xu
Congying Zhao
Xiaojun Su
Yaping Shen
Weiyue Gu
Xiaohong Kong
Ying Yang

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2021.699574

8,604 views
13 citations

Original Research

Published on 13 Aug 2021

Reelin Is Required for Maintenance of Granule Cell Lamination in the Healthy and Epileptic Hippocampus

in Brain Disease Mechanisms

Catarina Orcinha
Antje Kilias
Enya Paschen
Marie Follo
Carola A. Haas

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2021.730811

4,949 views
10 citations

Original Research

Published on 09 Aug 2021

Altered Cerebrospinal Fluid Clearance and Increased Intracranial Pressure in Rats 18 h After Experimental Cortical Ischaemia

in Brain Disease Mechanisms

Steven W. Bothwell
Daniel Omileke
Rebecca J. Hood
Debbie-Gai Pepperall
Sara Azarpeykan
Adjanie Patabendige
Neil J. Spratt

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2021.712779

5,904 views
8 citations

Review

Published on 09 Aug 2021

Potential Therapeutic Role of HDAC Inhibitors in FUS-ALS

in Brain Disease Mechanisms

Clara Tejido
Donya Pakravan
Ludo Van Den Bosch

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2021.686995

9,049 views
18 citations

Brief Research Report

Published on 09 Aug 2021

Miro1 Impairment in a Parkinson’s At-Risk Cohort

in Brain Disease Mechanisms

David Nguyen
Vinita Bharat
Devon M. Conradson
Pawan Nandakishore
Xinnan Wang

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2021.734273

6,195 views
10 citations

Mini Review

Published on 04 Aug 2021

Long Noncoding RNAs in Neurodegenerative Diseases: Pathogenesis and Potential Implications as Clinical Biomarkers

in Brain Disease Mechanisms

Meng Zhang
Ping He
Zhigang Bian

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2021.685143

7,566 views
44 citations

Original Research

Published on 27 Jul 2021

The Potential Effect of Nav1.8 in Autism Spectrum Disorder: Evidence From a Congenital Case With Compound Heterozygous SCN10A Mutations

in Brain Disease Mechanisms

Björn Heinrichs
Baowen Liu
Jin Zhang
Jannis E. Meents
Kim Le
Andelain Erickson
Petra Hautvast
Xiwen Zhu
Ningbo Li
Yi Liu

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2021.709228

5,355 views
2 citations

Original Research

Published on 26 Jul 2021

Lovastatin Alleviates α-Synuclein Aggregation and Phosphorylation in Cellular Models of Synucleinopathy

in Brain Disease Mechanisms

Lijun Dai
Jiannan Wang
Mingyang He
Min Xiong
Ye Tian
Chaoyang Liu
Zhentao Zhang

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2021.682320

5,715 views
12 citations

Review

Published on 23 Jul 2021

Tweaking Progranulin Expression: Therapeutic Avenues and Opportunities

in Brain Disease Mechanisms

Joke Terryn
Catherine M. Verfaillie
Philip Van Damme

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2021.713031

17,222 views
32 citations

Original Research

Published on 19 Jul 2021

Expression Analysis of Ermin and Listerin E3 Ubiquitin Protein Ligase 1 Genes in Autistic Patients

in Brain Disease Mechanisms

Shadi Shiva
Jalal Gharesouran
Hani Sabaie
Mohammad Reza Asadi
Shahram Arsang-Jang
Mohammad Taheri
Maryam Rezazadeh

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2021.701977

3,826 views
5 citations

Mini Review

Published on 16 Jul 2021

Investigating Post-translational Modifications in Neuropsychiatric Disease: The Next Frontier in Human Post-mortem Brain Research

in Brain Disease Mechanisms

Melanie J. Grubisha
Robert A. Sweet
Matthew L. MacDonald

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2021.689495

6,035 views
4 citations

Original Research

Published on 09 Jul 2021

Age-Related Transcriptional Deregulation of Genes Coding Synaptic Proteins in Alzheimer's Disease Murine Model: Potential Neuroprotective Effect of Fingolimod

in Brain Disease Mechanisms

Henryk Jęśko
Iga Wieczorek
Przemysław Leonard Wencel
Magdalena Gąssowska-Dobrowolska
Walter J. Lukiw
Robert Piotr Strosznajder

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2021.660104

5,266 views
15 citations

Mini Review

Published on 08 Jul 2021

Harnessing the Activation of RIG-I Like Receptors to Inhibit Glioblastoma Tumorigenesis

in Brain Disease Mechanisms

Francesca Bufalieri
Irene Basili
Lucia Di Marcotullio
Paola Infante

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2021.710171

4,307 views
8 citations

Original Research

Published on 06 Jul 2021

Risperidone Mitigates Enhanced Excitatory Neuronal Function and Repetitive Behavior Caused by an ASD-Associated Mutation of SIK1

in Brain Disease Mechanisms

Moataz Badawi
Takuma Mori
Taiga Kurihara
Takahiro Yoshizawa
Katsuhiro Nohara
Emi Kouyama-Suzuki
Toru Yanagawa
Yoshinori Shirai
Katsuhiko Tabuchi

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2021.706494

4,733 views
14 citations

Mini Review

Published on 05 Jul 2021

The Metallome as a Link Between the “Omes” in Autism Spectrum Disorders

in Brain Disease Mechanisms

Janelle E. Stanton
Sigita Malijauskaite
Kieran McGourty
Andreas M. Grabrucker

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2021.695873

6,246 views
10 citations

Review

Published on 01 Jul 2021

The Molecular Basis of Depression: Implications of Sex-Related Differences in Epigenetic Regulation

in Brain Disease Mechanisms

Ayako Kawatake-Kuno
Toshiya Murai
Shusaku Uchida

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2021.708004

9,134 views
15 citations

Navigation group

Articles

Application of Trio-Whole Exome Sequencing in Genetic Diagnosis and Therapy in Chinese Children With Epilepsy

Reelin Is Required for Maintenance of Granule Cell Lamination in the Healthy and Epileptic Hippocampus

Altered Cerebrospinal Fluid Clearance and Increased Intracranial Pressure in Rats 18 h After Experimental Cortical Ischaemia

Potential Therapeutic Role of HDAC Inhibitors in FUS-ALS

Miro1 Impairment in a Parkinson’s At-Risk Cohort

Long Noncoding RNAs in Neurodegenerative Diseases: Pathogenesis and Potential Implications as Clinical Biomarkers

The Potential Effect of Nav1.8 in Autism Spectrum Disorder: Evidence From a Congenital Case With Compound Heterozygous SCN10A Mutations

Lovastatin Alleviates α-Synuclein Aggregation and Phosphorylation in Cellular Models of Synucleinopathy

Tweaking Progranulin Expression: Therapeutic Avenues and Opportunities

Expression Analysis of Ermin and Listerin E3 Ubiquitin Protein Ligase 1 Genes in Autistic Patients

Investigating Post-translational Modifications in Neuropsychiatric Disease: The Next Frontier in Human Post-mortem Brain Research

Age-Related Transcriptional Deregulation of Genes Coding Synaptic Proteins in Alzheimer's Disease Murine Model: Potential Neuroprotective Effect of Fingolimod

Harnessing the Activation of RIG-I Like Receptors to Inhibit Glioblastoma Tumorigenesis

Risperidone Mitigates Enhanced Excitatory Neuronal Function and Repetitive Behavior Caused by an ASD-Associated Mutation of SIK1

The Metallome as a Link Between the “Omes” in Autism Spectrum Disorders

The Molecular Basis of Depression: Implications of Sex-Related Differences in Epigenetic Regulation