Original Research

Published on 10 Mar 2022

Hyperphosphorylated Human Tau Accumulates at the Synapse, Localizing on Synaptic Mitochondrial Outer Membranes and Disrupting Respiration in a Mouse Model of Tauopathy

in Brain Disease Mechanisms

Andrew J. Trease
Joseph W. George
Nashanthea J. Roland
Eliezer Z. Lichter
Katy Emanuel
Steven Totusek
Howard S. Fox
Kelly L. Stauch

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2022.852368

4,867 views
17 citations

Review

Published on 10 Mar 2022

Modeling Epilepsy Using Human Induced Pluripotent Stem Cells-Derived Neuronal Cultures Carrying Mutations in Ion Channels and the Mechanistic Target of Rapamycin Pathway

in Brain Disease Mechanisms

Octavia Yifang Weng
Yun Li
Lu-Yang Wang

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2022.810081

5,704 views
2 citations

Original Research

Published on 09 Mar 2022

Characterisation of the Function of a SINE-VNTR-Alu Retrotransposon to Modulate Isoform Expression at the MAPT Locus

in Brain Disease Mechanisms

Alexander Fröhlich
Abigail L. Pfaff
Vivien J. Bubb
Sulev Koks
John P. Quinn

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2022.815695

4,192 views
12 citations

Review

Published on 08 Mar 2022

Role of Semaphorins in Ischemic Stroke

in Brain Disease Mechanisms

Huaping Du
Yuan Xu
Li Zhu

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2022.848506

4,416 views
9 citations

Original Research

Published on 03 Mar 2022

Expression of Circ_Satb1 Is Decreased in Mesial Temporal Lobe Epilepsy and Regulates Dendritic Spine Morphology

in Brain Disease Mechanisms

Andreia Gomes-Duarte
Morten T. Venø
Marina de Wit
Ketharini Senthilkumar
Mark H. Broekhoven
Joëlle van den Herik
Fleur R. Heeres
Daniëlle van Rossum
Mateja Rybiczka-Tesulov
Ivano Legnini

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2022.832133

5,085 views
12 citations

Original Research

Published on 02 Mar 2022

Blood SSR1: A Possible Biomarker for Early Prediction of Parkinson’s Disease

in Brain Disease Mechanisms

Wen Zhang
Jiabing Shen
Yuhui Wang
Kefu Cai
Qi Zhang
Maohong Cao

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2022.762544

5,049 views
6 citations

Original Research

Published on 25 Feb 2022

Type I Interferon Response Is Mediated by NLRX1-cGAS-STING Signaling in Brain Injury

in Brain Disease Mechanisms

Lauren E. Fritsch
Jing Ju
Erwin Kristobal Gudenschwager Basso
Eman Soliman
Swagatika Paul
Jiang Chen
Alexandra M. Kaloss
Elizabeth A. Kowalski
Taylor C. Tuhy
Rachana Deven Somaiya

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2022.852243

8,323 views
23 citations

Original Research

Published on 24 Feb 2022

Increasing Severity of Spinal Cord Injury Results in Microglia/Macrophages With Annular-Shaped Morphology and No Change in Expression of CD40 and Tumor Growth Factor-β During the Chronic Post-injury Stage

in Brain Disease Mechanisms

Elvira Ruslanovna Akhmetzyanova
Anna Viktorovna Timofeeva
Davran Khudaishukurovich Sabirov
Alexander Alexandrovich Kostennikov
Alexander Alexandrovich Rogozhin
Victoria James
S. S. Arkhipova
Albert Anatolevich Rizvanov
Yana Olegovna Mukhamedshina

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2021.802558

3,111 views
5 citations

Original Research

Published on 24 Feb 2022

Novel Intronic Mutations of TBK1 Promote Aberrant Splicing Modes in Amyotrophic Lateral Sclerosis

in Brain Disease Mechanisms

Ying-Qian Lu
Jian-Min Chen
Han Lin
Shu-Yan Feng
Chun-Hui Che
Chang-Yun Liu
Hua-Pin Huang
Zhang-Yu Zou

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2022.691534

3,231 views
6 citations

Editorial

Published on 18 Feb 2022

Editorial: Autism Spectrum Disorders and Metal Dyshomeostasis

in Brain Disease Mechanisms

Mukesh K. Pandey
Andreas M. Grabrucker
Sunil Q. Mehta
Robert J. Harvey

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2022.861483

2,009 views
1 citation

Original Research

Published on 16 Feb 2022

Impaired Glucose Homeostasis in a Tau Knock-In Mouse Model

in Brain Disease Mechanisms

Hamza Benderradji
Sarra Kraiem
Emilie Courty
Sabiha Eddarkaoui
Cyril Bourouh
Emilie Faivre
Laure Rolland
Emilie Caron
Mélanie Besegher
Frederik Oger

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2022.841892

4,990 views
5 citations

Mini Review

Published on 16 Feb 2022

Electrophysiological Properties of Human Cortical Organoids: Current State of the Art and Future Directions

in Brain Disease Mechanisms

Clara Zourray
Manju A. Kurian
Serena Barral
Gabriele Lignani

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2022.839366

10,183 views
7 citations

Review

Published on 15 Feb 2022

New Insights Into the Pivotal Role of CREB-Regulated Transcription Coactivator 1 in Depression and Comorbid Obesity

in Brain Disease Mechanisms

Clara Rossetti
Antoine Cherix
Laetitia F. Guiraud
Jean-René Cardinaux

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2022.810641

5,818 views
9 citations

Correction

Published on 14 Feb 2022

Corrigendum: Evaluation of Zn, Cu, and Se Levels in the North American Autism Spectrum Disorder Population

in Brain Disease Mechanisms

Sunil Q. Mehta
Supriya Behl
Patrick L. Day
Adriana M. Delgado
Nicholas B. Larson
Lindsay R. Stromback
Andrea R. Huebner
Timothy R. DeGrado
Jessica M. Davis
Paul J. Jannetto

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2022.831799

1,527 views
1 citation

Original Research

Published on 14 Feb 2022

14-3-3 Dysfunction in Dorsal Hippocampus CA1 (dCA1) Induces Psychomotor Behavior via a dCA1-Lateral Septum-Ventral Tegmental Area Pathway

in Brain Disease Mechanisms

Jiajing Zhang
Meaghan Navarrete
Yuying Wu
Yi Zhou

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2022.817227

4,194 views
5 citations

Original Research

Published on 11 Feb 2022

Amyloid Beta Is Internalized via Macropinocytosis, an HSPG- and Lipid Raft-Dependent and Rac1-Mediated Process

in Brain Disease Mechanisms

Keyoumu Nazere
Tetsuya Takahashi
Naoyuki Hara
Kazuki Muguruma
Masahiro Nakamori
Yu Yamazaki
Hiroyuki Morino
Hirofumi Maruyama

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2022.804702

5,623 views
11 citations

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Articles

Hyperphosphorylated Human Tau Accumulates at the Synapse, Localizing on Synaptic Mitochondrial Outer Membranes and Disrupting Respiration in a Mouse Model of Tauopathy

Modeling Epilepsy Using Human Induced Pluripotent Stem Cells-Derived Neuronal Cultures Carrying Mutations in Ion Channels and the Mechanistic Target of Rapamycin Pathway

Characterisation of the Function of a SINE-VNTR-Alu Retrotransposon to Modulate Isoform Expression at the MAPT Locus

Role of Semaphorins in Ischemic Stroke

Expression of Circ_Satb1 Is Decreased in Mesial Temporal Lobe Epilepsy and Regulates Dendritic Spine Morphology

Blood SSR1: A Possible Biomarker for Early Prediction of Parkinson’s Disease

Type I Interferon Response Is Mediated by NLRX1-cGAS-STING Signaling in Brain Injury

Increasing Severity of Spinal Cord Injury Results in Microglia/Macrophages With Annular-Shaped Morphology and No Change in Expression of CD40 and Tumor Growth Factor-β During the Chronic Post-injury Stage

Novel Intronic Mutations of TBK1 Promote Aberrant Splicing Modes in Amyotrophic Lateral Sclerosis

Editorial: Autism Spectrum Disorders and Metal Dyshomeostasis

Impaired Glucose Homeostasis in a Tau Knock-In Mouse Model

Electrophysiological Properties of Human Cortical Organoids: Current State of the Art and Future Directions

New Insights Into the Pivotal Role of CREB-Regulated Transcription Coactivator 1 in Depression and Comorbid Obesity

Corrigendum: Evaluation of Zn, Cu, and Se Levels in the North American Autism Spectrum Disorder Population

14-3-3 Dysfunction in Dorsal Hippocampus CA1 (dCA1) Induces Psychomotor Behavior via a dCA1-Lateral Septum-Ventral Tegmental Area Pathway

Amyloid Beta Is Internalized via Macropinocytosis, an HSPG- and Lipid Raft-Dependent and Rac1-Mediated Process