Frontiers in Molecular Biosciences

Original Research

Published on 14 Feb 2023

Whole genome sequencing of Malaysian colorectal cancer patients reveals specific druggable somatic mutations

Ryia Illani Mohd Yunos
Nurul-Syakima Ab Mutalib
Jia-shiun Khoo
Sazuita Saidin
Muhiddin Ishak
Saiful Effendi Syafruddin
Francis Yew Fu Tieng
Najwa Farhah Md Yusof
Mohd Ridhwan Abd Razak
Norshahidah Mahamad Nadzir

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.997747

4,316 views
3 citations

Review

Published on 03 Feb 2023

Hsp70.1 carbonylation induces lysosomal cell death for lifestyle-related diseases

Tetsumori Yamashima
Takuya Seike
Shinji Oikawa
Hatasu Kobayashi
Hidenori Kido
Masahiro Yanagi
Daisuke Yamamiya
Shihui Li
Piyakarn Boontem
Eishiro Mizukoshi

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.1063632

4,806 views
11 citations

Original Research

Published on 23 Jan 2023

In silico prediction of molecular mechanisms of toxicity mediated by the leptospiral PF07598 gene family-encoded virulence-modifying proteins

Reetika Chaurasia
Joseph M. Vinetz

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.1092197

4,900 views
6 citations

Original Research

Published on 19 Jan 2023

Disruption of DYRK1A-induced hyperphosphorylation of amyloid-beta and tau protein in Alzheimer’s disease: An integrative molecular modeling approach

Rohit Shukla
Anuj Kumar
David J. Kelvin
Tiratha Raj Singh

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.1078987

5,389 views
7 citations

Mini Review

Published on 17 Jan 2023

KODAMA exploratory analysis in metabolic phenotyping

Maria Mgella Zinga
Ebtesam Abdel-Shafy
Tadele Melak
Alessia Vignoli
Silvano Piazza
Luiz Fernando Zerbini
Leonardo Tenori
Stefano Cacciatore

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.1070394

3,389 views
2 citations

Correction

Published on 16 Jan 2023

Corrigendum: Phenotype-based drug screening: An in vivo strategy to classify and identify the chemical compounds modulating zebrafish M-cell regeneration

Ankita Kumari
Xin-An Zeng
Abdul Rahaman
Muhammad Adil Farooq
Yanyan Huang
Mahafooj Alee
Runyu Yao
Murtaza Ali
Ibrahim Khalifa
Omnia Badr

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.1081922

1,646 views

Review

Published on 13 Jan 2023

Recent advances in ferroptosis and therapeutic strategies for glioblastoma

Qixiong Lu
Xiaoyang Lu
Yuansheng Zhang
Wei Huang
Hu Zhou
Tao Li

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.1068437

4,218 views
4 citations

Hypothesis and Theory

Published on 13 Jan 2023

AlphaFold predicted structure of the Hsp90-like domains of the neurodegeneration linked protein sacsin reveals key residues for ATPase activity

Laura Perna
Matteo Castelli
Elena Frasnetti
Lisa E. L. Romano
Giorgio Colombo
Chrisostomos Prodromou
J. Paul Chapple

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.1074714

4,010 views
3 citations

Review

Published on 12 Jan 2023

Recent applications of computational methods to allosteric drug discovery

Rajiv Gandhi Govindaraj
Sundar Thangapandian
Michael Schauperl
Rajiah Aldrin Denny
David J. Diller

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.1070328

5,464 views
17 citations

Mini Review

Published on 12 Jan 2023

RNA polymerase III transcription and cancer: A tale of two RPC7 subunits

Ruiying Cheng
Kevin Van Bortle

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.1073795

4,174 views
6 citations

Original Research

Published on 12 Jan 2023

Big Data analytics for improved prediction of ligand binding and conformational selection

Shivangi Gupta
Jerome Baudry
Vineetha Menon

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.953984

2,698 views
2 citations

Original Research

Published on 12 Jan 2023

Transcription factor Ap2b regulates the mouse autosomal recessive polycystic kidney disease genes, Pkhd1 and Cys1

Maoqing Wu
Naoe Harafuji
Amber K. O’Connor
Ljubica Caldovic
Lisa M. Guay-Woodford

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.946344

3,329 views
3 citations

Original Research

Published on 12 Jan 2023

Innate immunity mediator STING modulates nascent DNA metabolism at stalled forks in human cells

Pavlo Lazarchuk
Vy N. Nguyen
Salomé Brunon
Maria N. Pavlova
Julia M. Sidorova

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.1048726

4,098 views
4 citations

Editorial

Published on 11 Jan 2023

Editorial: Exosomal biomarkers: Roles in diagnostics and therapeutics

Dwijendra K. Gupta

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.1127540

1,364 views
1 citation

Review

Published on 11 Jan 2023

Current research on fungi in chronic wounds

Yumei Ge
Qingqing Wang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.1057766

16,686 views
34 citations

Original Research

Published on 11 Jan 2023

Plasma enzymatic activity, proteomics and peptidomics in COVID-19-induced sepsis: A novel approach for the analysis of hemostasis

Fernando Dos Santos
Joyce B. Li
Nathalia Juocys
Rafi Mazor
Laura Beretta
Nicole G. Coufal
Michael T. Y. Lam
Mazen F. Odish
Maria Claudia Irigoyen
Anthony J. O’Donoghue

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.1051471

2,924 views
7 citations