Frontiers in Molecular Biosciences

Original Research

Published on 10 Jul 2015

The use of ion mobility mass spectrometry to probe modulation of the structure of p53 and of MDM2 by small molecule inhibitors

in Structural Biology

Eleanor Rose Dickinson
Ewa Jurneczko
Judith Nicholson
Ted Hupp
Joanna Zawacka-Pankau
Galina Selivanova
Perdita Elizabeth Barran

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2015.00039

6,013 views
33 citations

Perspective

Published on 09 Jul 2015

Globular and disordered – the non-identical twins in protein-protein interactions

in Structural Biology

Kaare Teilum
Johan G. Olsen
Birthe B. Kragelund

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2015.00040

7,767 views
42 citations

Review

Published on 27 May 2015

Protein flexibility in the light of structural alphabets

in Structural Biology

Pierrick Craveur
Agnel Praveen Joseph
Jeremy Esque
Tarun JaiRaj Narwani
Floriane Noel
Nicolas Shinada
Matthieu Goguet
Léonard Sylvain
Pierre Poulain
Olivier Bertrand

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2015.00020

19,031 views
83 citations

Original Research

Published on 21 May 2015

Crystal structure of the magnetobacterial protein MtxA C-terminal domain reveals a new sequence-structure relationship

in Structural Biology

Geula Davidov
Frank D. Müller
Jens Baumgartner
Ronit Bitton
Damien Faivre
Dirk Schüler
Raz Zarivach

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2015.00025

5,355 views
2 citations

Perspective

Published on 21 May 2015

Evolution and intelligent design in drug development

in Structural Biology

Roman V. Agafonov
Christopher Wilson
Dorothee Kern

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2015.00027

8,993 views
12 citations

Mini Review

Published on 19 May 2015

Exploring intrinsically disordered proteins using site-directed spin labeling electron paramagnetic resonance spectroscopy

in Structural Biology

Nolwenn Le Breton
Marlène Martinho
Elisabetta Mileo
Emilien Etienne
Guillaume Gerbaud
Bruno Guigliarelli
Valérie Belle

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2015.00021

7,997 views
45 citations

Review

Published on 19 May 2015

Fairy “tails”: flexibility and function of intrinsically disordered extensions in the photosynthetic world

in Structural Biology

Gabriel Thieulin-Pardo
Luisana Avilan
Mila Kojadinovic
Brigitte Gontero

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2015.00023

7,839 views
24 citations

Hypothesis and Theory

Published on 28 Apr 2015

Alternative salt bridge formation in Aβ—a hallmark of early-onset Alzheimer's disease?

in Structural Biology

Maarten Schledorn
Beat H. Meier
Anja Böckmann

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2015.00014

5,071 views
17 citations

Review

Published on 28 Apr 2015

From protein structure to function via single crystal optical spectroscopy

in Structural Biology

Luca Ronda
Stefano Bruno
Stefano Bettati
Paola Storici
Andrea Mozzarelli

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2015.00012

9,113 views
16 citations

Original Research

Published on 23 Mar 2015

Quantifying the role of chaperones in protein translocation by computational modeling

in Structural Biology

Salvatore Assenza
Paolo De Los Rios
Alessandro Barducci

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2015.00008

5,173 views
7 citations

Review

Published on 04 Mar 2015

Phylogenetic analysis of vitamin B12-related metabolism in Mycobacterium tuberculosis

in Structural Biology

Douglas B. Young
Iñaki Comas
Luiz P. S. de Carvalho

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2015.00006

13,684 views
34 citations

Original Research

Published on 05 Feb 2015

Allosteric regulation of deubiquitylase activity through ubiquitination

in Structural Biology

Serena Faggiano
Rajesh P. Menon
Geoff P. Kelly
Sokol V. Todi
K. Matthew Scaglione
Petr V. Konarev
Dmitri I. Svergun
Henry L. Paulson
Annalisa Pastore

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2015.00002

5,986 views
17 citations

Review

Published on 19 Dec 2014

Ser or Leu: structural snapshots of mistranslation in Candida albicans

in Structural Biology

Zsuzsa Sárkány
Alexandra Silva
Pedro J. B. Pereira
Sandra Macedo-Ribeiro

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2014.00027

5,410 views
10 citations

Original Research

Published on 28 Oct 2014

Endophilin-A1 BAR domain interaction with arachidonyl CoA

in Structural Biology

Maxim V. Petoukhov
Winfried Weissenhorn
Dmitri I. Svergun

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2014.00020

4,853 views
3 citations

Original Research

Published on 07 Oct 2014

The conformation of enkephalin bound to its receptor: an “elusive goal” becoming reality

in Structural Biology

Domenico Sanfelice
Piero A. Temussi

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2014.00014

5,326 views
8 citations

Original Research

Published on 30 Sep 2014

Trapping a salt-dependent unfolding intermediate of the marginally stable protein Yfh1

in Structural Biology

Bartolomé Vilanova
Domenico Sanfelice
Gabriel Martorell
Piero A. Temussi
Annalisa Pastore

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2014.00013

4,432 views
13 citations