Frontiers in Molecular Biosciences

Review

Published on 19 Jun 2018

Functional Mechanism of the Efflux Pumps Transcription Regulators From Pseudomonas aeruginosa Based on 3D Structures

in Structural Biology

Karim Housseini B Issa
Gilles Phan
Isabelle Broutin

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2018.00057

23,324 views
59 citations

Review

Published on 12 Jun 2018

Biochemical Properties of Human D-amino Acid Oxidase Variants and Their Potential Significance in Pathologies

in Structural Biology

Silvia Sacchi
Pamela Cappelletti
Giulia Murtas

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2018.00055

6,367 views
31 citations

Original Research

Published on 12 Jun 2018

Ligand-Induced Variations in Structural and Dynamical Properties Within an Enzyme Superfamily

in Structural Biology

Chitra Narayanan
David N. Bernard
Khushboo Bafna
Donald Gagné
Pratul K. Agarwal
Nicolas Doucet

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2018.00054

3,865 views
21 citations

Protocols

Published on 04 Jun 2018

Benchmarking cryo-EM Single Particle Analysis Workflow

in Structural Biology

Laura Y. Kim
William J. Rice
Edward T. Eng
Mykhailo Kopylov
Anchi Cheng
Ashleigh M. Raczkowski
Kelsey D. Jordan
Daija Bobe
Clinton S. Potter
Bridget Carragher

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2018.00050

20,542 views
41 citations

Review

Published on 25 May 2018

Thermodynamic and NMR Assessment of Ligand Cooperativity and Intersubunit Communication in Symmetric Dimers: Application to Thymidylate Synthase

in Structural Biology

Andrew L. Lee
Paul J. Sapienza

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2018.00047

3,434 views
13 citations

Review

Published on 14 May 2018

The Mechanisms of Action of Ribosome-Targeting Peptide Antibiotics

in Structural Biology

Yury S. Polikanov
Nikolay A. Aleksashin
Bertrand Beckert
Daniel N. Wilson

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2018.00048

48,353 views
104 citations

Mini Review

Published on 30 Apr 2018

Intramolecular Fuzzy Interactions Involving Intrinsically Disordered Domains

in Structural Biology

Miguel Arbesú
Guillermo Iruela
Héctor Fuentes
João M. C. Teixeira
Miquel Pons

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2018.00039

7,906 views
74 citations

Original Research

Published on 19 Apr 2018

Stabilization of a Membrane-Associated Amyloid-β Oligomer for Its Validation in Alzheimer's Disease

in Structural Biology

Montserrat Serra-Batiste
James Tolchard
Fabrice Giusti
Manuela Zoonens
Natàlia Carulla

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2018.00038

4,880 views
13 citations

Mini Review

Published on 11 Apr 2018

The Use of NMR to Study Transient Carbohydrate—Protein Interactions

in Structural Biology

Pedro M. Nieto

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2018.00033

4,301 views
14 citations

Review

Published on 06 Apr 2018

A Three-Ring Circus: Metabolism of the Three Proteogenic Aromatic Amino Acids and Their Role in the Health of Plants and Animals

in Structural Biology

Anutthaman Parthasarathy
Penelope J. Cross
Renwick C. J. Dobson
Lily E. Adams
Michael A. Savka
André O. Hudson

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2018.00029

96,021 views
262 citations

Original Research

Published on 02 Mar 2018

Independent Evolution of Strychnine Recognition by Bitter Taste Receptor Subtypes

in Structural Biology

Ava Yuan Xue
Antonella Di Pizio
Anat Levit
Tali Yarnitzky
Osnat Penn
Tal Pupko
Masha Y. Niv

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2018.00009

5,891 views
15 citations

Review

Published on 23 Feb 2018

Structural and Mechanistic Basis for Extended-Spectrum Drug-Resistance Mutations in Altering the Specificity of TEM, CTX-M, and KPC β-lactamases

in Structural Biology

Timothy Palzkill

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2018.00016

31,088 views
156 citations

Mini Review

Published on 13 Feb 2018

Focus on the Role of D-serine and D-amino Acid Oxidase in Amyotrophic Lateral Sclerosis/Motor Neuron Disease (ALS)

in Structural Biology

Nazanin R. Kondori
Praveen Paul
Jacqueline P. Robbins
Ke Liu
John C. W. Hildyard
Dominic J. Wells
Jacqueline S. de Belleroche

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2018.00008

8,763 views
25 citations

Original Research

Published on 13 Feb 2018

Positive Charges on the Surface of Thaumatin Are Crucial for the Multi-Point Interaction with the Sweet Receptor

in Structural Biology

Tetsuya Masuda
Satomi Kigo
Mayuko Mitsumoto
Keisuke Ohta
Mamoru Suzuki
Bunzo Mikami
Naofumi Kitabatake
Fumito Tani

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2018.00010

6,488 views
14 citations

Original Research

Published on 13 Feb 2018

Re-sensitizing Multidrug Resistant Bacteria to Antibiotics by Targeting Bacterial Response Regulators: Characterization and Comparison of Interactions between 2-Aminoimidazoles and the Response Regulators BfmR from Acinetobacter baumannii and QseB from Francisella spp.

in Structural Biology

Morgan E. Milton
Bradley M. Minrovic
Danni L. Harris
Brian Kang
David Jung
Caleb P. Lewis
Richele J. Thompson
Roberta J. Melander
Daina Zeng
Christian Melander

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2018.00015

7,913 views
27 citations

Perspective

Published on 08 Feb 2018

Free Energy, Enthalpy and Entropy from Implicit Solvent End-Point Simulations

in Structural Biology

Federico Fogolari
Alessandra Corazza
Gennaro Esposito

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2018.00011

17,663 views
22 citations