Frontiers in Molecular Biosciences | Molecular Diagnostics and Therapeutics

Hypothesis and Theory

Published on 25 Feb 2025

Jianpi Yangzheng Xiaozheng granule induced ferroptosis to suppress gastric cancer progression through reprogramming lipid metabolism via SCD1/Wnt/β-catenin axis

in Molecular Diagnostics and Therapeutics

Xiangyang Wang
Jingxiao Li
Rong Qin
Yi Yin
Jiepin Li
Sitian Lin
Xi Zou

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1523494

1,476 views

Correction

Published on 25 Feb 2025

Corrigendum: Role of ARRB1 in prognosis and immunotherapy: a pan-cancer analysis

in Molecular Diagnostics and Therapeutics

Yingquan Ye
Haili Jiang
Yue Wu
Gaoxiang Wang
Yi Huang
Weijie Sun
Mei Zhang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1577764

418 views

Correction

Accepted on 21 Feb 2025

Corrigendum: Resveratrol improves mitochondrial biogenesisfunction and activates PGC-1α pathway in a preclinical model of early brain injury following subarachnoid hemorrhage

in Molecular Diagnostics and Therapeutics

Jian Zhou
Zaijia Yang
Ruiming Shen
Huiduan Zhen
Wangwang Zhong
Zhenggang Chen
Jianjian Tang
Juan Zhu

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1402935

293 views

Original Research

Published on 20 Feb 2025

Immunomagnetic enrichment coupled to PAX8/TP53 molecular pathology approach increases sensitivity in the detection of ovarian cancer cells in ascites

in Molecular Diagnostics and Therapeutics

Ivana Kurelac
Manuela Sollazzo
Monica De Luise
Francesca Nanetti
Laura Lanteri
Luigi D’Angelo
Beatrice Cavina
Simona Corrà
Stefano Miglietta
Sara Milioni

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1537407

767 views

Editorial

Published on 19 Feb 2025

Editorial: Experimental and computational methods in the development of diagnostics and therapeutics for colon cancer

in Molecular Diagnostics and Therapeutics

Muhammad Suleman
Shahid Ali
Farooq Rashid
Faez Iqbal Khan

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1568721

736 views

Original Research

Published on 17 Feb 2025

Genome-wide CRISPR/Cas9 screening identifies key profibrotic regulators of TGF-β1-induced epithelial-mesenchymal transformation and pulmonary fibrosis

in Molecular Diagnostics and Therapeutics

Chunjiang Tan
Juan Wang
Xiangrong Ye
Kaidirina Kasimu
Ye Li
Feng Luo
Hui Yi
Yifeng Luo

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1507163

1,647 views

Original Research

Published on 14 Feb 2025

A CRISPR-Cas-based recombinase polymerase amplification assay for ultra-sensitive detection of active Trypanosoma brucei evansi infections

in Molecular Diagnostics and Therapeutics

Andrés Álvarez-Rodríguez
Zeng Li
Bo-Kyung Jin
Benoit Stijlemans
Peter Geldhof
Stefan Magez

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1512970

1,292 views

Original Research

Published on 14 Feb 2025

An unfolded protein response (UPR)-signature regulated by the NFKB–miR-29b/c axis fosters tumor aggressiveness and poor survival in bladder cancer

in Molecular Diagnostics and Therapeutics

Jian Zhang
Xiaosong Fan
Yu Chen
Yichao Han
Weixing Yu
Shaolin Zhang
Bicheng Yang
Junlong Zhang
Yanling Chen

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1542650

1,137 views

Original Research

Published on 13 Feb 2025

Calcium-dependent adhesion protein CDH18, a potential biomarker for prognosis in uterine corpus endometrial carcinoma

in Molecular Diagnostics and Therapeutics

Xiaoxuan Tang
Shanxing Dang
Jie Qiu
Ruilan Zhou
Jing Ling
Limei Zhang
Xiaopeng Peng
Qingyun Li
Jin Liu
Wei Liao

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1530253

1,405 views

Original Research

Published on 11 Feb 2025

IL-6/GATA2/SERPINE1 pathway is implicated in regulating cellular senescence after acute kidney injury

in Molecular Diagnostics and Therapeutics

Hongshuang Su
Xiaoxi Lin
Ayinuer Paredong
Congcong Yao
Yan Zhang
Mengke Geng
Yuqian Guan
Lichao Gong
Feng Jiang
Qi Lv

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1538526

1,490 views

Original Research

Published on 11 Feb 2025

Homologous recombination deficiency test validation in patients with high-grade advanced ovarian cancer

in Molecular Diagnostics and Therapeutics

Angelica Nogueira Rodrigues
Andreza Karine de Barros Almeida Souto
Diocésio Alves Pinto de Andrade
Larissa Müller Gomes
Sandra Satie Koide
Renata de Godoy e Silva
Bruno Batista de Souza
Juliana Doblas Massaro
Andréia Cristina de Melo
Andrea Morais Borges

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1524594

1,009 views

Original Research

Published on 07 Feb 2025

Defining the high-risk category of patients with cutaneous melanoma: a practical tool based on prognostic modeling

in Molecular Diagnostics and Therapeutics

Oleksandr Dudin
Ozar Mintser
Vitalii Gurianov
Nazarii Kobyliak
Denys Kozakov
Sofiia Livshun
Oksana Sulaieva

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1543148

967 views

Original Research

Published on 07 Feb 2025

Serum glutathione peroxidase-3 concentration at diagnosis as a biomarker for assessing disease activity and damage of antineutrophil cytoplasmic antibody-associated vasculitis at diagnosis

in Molecular Diagnostics and Therapeutics

Jihye Chung
Jang Woo Ha
Yong-Beom Park
Sang-Won Lee

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1549454

908 views

Original Research

Published on 06 Feb 2025

Deciphering the role of miRNA-mRNA interactions in cerebral vasospasm post intracranial hemorrhage

in Molecular Diagnostics and Therapeutics

Xiang Chu
Xiyan Zhu
Honghao Xu
Wenbing Zhao
Debin Guo
Xing Chen
Jinze Wu
Lei Li
Hao Wang
Jun Fei

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1492729

1,018 views

Review

Published on 06 Feb 2025

The diagnostic and prognostic significance of HOXC13-AS and its molecular regulatory mechanism in human cancer

in Molecular Diagnostics and Therapeutics

Xiaosi Gu
Xin Hu
Sijia Zhang
Xiaoyu Zhang
Yong Wang
Lianlian Li

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1540048

985 views

Review

Published on 04 Feb 2025

The role of potential oxidative biomarkers in the prognosis of intracerebral hemorrhage and the exploration antioxidants as possible preventive and treatment options

in Molecular Diagnostics and Therapeutics

Jiayong Yao
Xiaohong Dai
Xueping Yv
Lei Zheng
Jia Zheng
Binglin Kuang
Wei Teng
Weiwei Yu
Mingyue Li
Hongtao Cao

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1541230

909 views