Original Research

Published on 07 Jun 2023

Multi-omic analysis of glycolytic signatures: exploring the predictive significance of heterogeneity and stemness in immunotherapy response and outcomes in hepatocellular carcinoma

in Molecular Diagnostics and Therapeutics

Shiyu Zhang
Yangting Pei
Feng Zhu

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1210111

2,342 views
1 citation

Editorial

Published on 06 Jun 2023

Editorial: Using multi-omics to develop new strategies to improve prognosis and immunotherapy outcomes in cancers

in Molecular Diagnostics and Therapeutics

Chenxi Cao
Shuang Chen
Libo Wang
Zaoqu Liu
Xinwei Han

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1190116

2,378 views

Original Research

Published on 02 Jun 2023

Identification of novel candidate targets for suppressing ovarian cancer progression through IL-33/ST2 axis components using the system biology approach

in Molecular Diagnostics and Therapeutics

Geovanny Genaro Reivan Ortiz
Carmen Iulia Ciongradi
M. V. N. L. Chaitanya
Jayasankar Narayanan
Mohamed Mohany
Salim S. Al-Rejaie
José Luis Arias-Gonzáles
Ioan Sârbu
Marjan Assefi
Shaik Vaseem Akram

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1189527

4,543 views
3 citations

Review

Published on 01 Jun 2023

PI3K/Akt/Nrf2 mediated cellular signaling and virus-host interactions: latest updates on the potential therapeutic management of SARS-CoV-2 infection

in Molecular Diagnostics and Therapeutics

V. S. Lekshmi
Kumari Asha
Melvin Sanicas
Abhila Asi
U. M. Arya
Binod Kumar

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1158133

4,483 views
9 citations

Original Research

Published on 01 Jun 2023

Hydroxyurea pharmacokinetics and precision dosing in low-resource settings

in Molecular Diagnostics and Therapeutics

Luke R. Smart
Mwesige Charles
Kathryn E. McElhinney
Min Dong
Alexandra Power-Hays
Thad Howard
Alexander A. Vinks
Emmanuela E. Ambrose
Russell E. Ware

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1130206

2,096 views
3 citations

Original Research

Published on 01 Jun 2023

Circulating neutrophils activated by cancer cells and M2 macrophages promote gastric cancer progression during PD-1 antibody-based immunotherapy

in Molecular Diagnostics and Therapeutics

Chenfei Zhou
Liting Guo
Qu Cai
Wenqi Xi
Fei Yuan
Huan Zhang
Chao Yan
Lei Huang
Zhenggang Zhu
Jun Zhang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1081762

4,710 views
6 citations

Review

Published on 31 May 2023

lncRNAs-EZH2 interaction as promising therapeutic target in cutaneous melanoma

in Molecular Diagnostics and Therapeutics

Michal Wozniak
Malgorzata Czyz

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1170026

2,859 views
4 citations

Original Research

Published on 31 May 2023

Single-cell RNA-seq uncovers distinct pathways and genes in endothelial cells during atherosclerosis progression

in Molecular Diagnostics and Therapeutics

Min Wu
Yijin Wu
Shulin Tang
Jinsong Huang
Yueheng Wu

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1176267

5,830 views
3 citations

Original Research

Published on 30 May 2023

Identification of key signaling pathways and hub genes related to immune infiltration in Kawasaki disease with resistance to intravenous immunoglobulin based on weighted gene co-expression network analysis

in Molecular Diagnostics and Therapeutics

Yue Wang
Yinyin Cao
Yang Li
Meifen Yuan
Jin Xu
Jian Li

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1182512

2,936 views
1 citation

Editorial

Published on 30 May 2023

Editorial: Oxidative stress in degenerative bone and joint diseases: novel molecular mechanisms and therapeutic potential

in Molecular Diagnostics and Therapeutics

Jialiang Lin
Libo Jiang
Ji Tu
Xiangyang Wang
Weishi Li

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1213380

1,585 views

Original Research

Published on 26 May 2023

Prediction of prognosis and immunotherapy response in breast cancer based on neutrophil extracellular traps-related classification

in Molecular Diagnostics and Therapeutics

Jiajing Zhao
Xiaojun Xie

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1165776

3,904 views
12 citations

Review

Published on 26 May 2023

Casticin as potential anticancer agent: recent advancements in multi-mechanistic approaches

in Molecular Diagnostics and Therapeutics

Katya Carbone
Fabio Gervasi
Latipa Kozhamzharova
Nazgul Altybaeva
Eda Sönmez Gürer
Javad Sharifi-Rad
Christophe Hano
Daniela Calina

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1157558

4,237 views
5 citations

Methods

Published on 24 May 2023

Unsupervised neural network for single cell Multi-omics INTegration (UMINT): an application to health and disease

in Molecular Diagnostics and Therapeutics

Chayan Maitra
Dibyendu B. Seal
Vivek Das
Rajat K. De

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1184748

4,263 views
5 citations

Review

Published on 23 May 2023

DPP-4 inhibitors for treating T2DM - hype or hope? an analysis based on the current literature

in Molecular Diagnostics and Therapeutics

Kunika Saini
Smriti Sharma
Yousuf Khan

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1130625

30,172 views
39 citations

Original Research

Published on 23 May 2023

Identifying a novel cuproptosis-related necroptosis gene subtype-related signature for predicting the prognosis, tumor microenvironment, and immunotherapy of hepatocellular carcinoma

in Molecular Diagnostics and Therapeutics

Yuanxin Shi
Peng Qiu
Kai Zhao
Xiangyu Li
Yunxiang Feng
Zhengdong Deng
Jianming Wang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1165243

3,449 views

Methods

Published on 22 May 2023

Mass spectrometry imaging as an emerging tool for studying metabolism in human brain organoids

in Molecular Diagnostics and Therapeutics

Gerarda Cappuccio
Saleh M. Khalil
Sivan Osenberg
Feng Li
Mirjana Maletic-Savatic

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1181965

7,167 views
8 citations

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Articles

Multi-omic analysis of glycolytic signatures: exploring the predictive significance of heterogeneity and stemness in immunotherapy response and outcomes in hepatocellular carcinoma

Editorial: Using multi-omics to develop new strategies to improve prognosis and immunotherapy outcomes in cancers

Identification of novel candidate targets for suppressing ovarian cancer progression through IL-33/ST2 axis components using the system biology approach

PI3K/Akt/Nrf2 mediated cellular signaling and virus-host interactions: latest updates on the potential therapeutic management of SARS-CoV-2 infection

Hydroxyurea pharmacokinetics and precision dosing in low-resource settings

Circulating neutrophils activated by cancer cells and M2 macrophages promote gastric cancer progression during PD-1 antibody-based immunotherapy

lncRNAs-EZH2 interaction as promising therapeutic target in cutaneous melanoma

Single-cell RNA-seq uncovers distinct pathways and genes in endothelial cells during atherosclerosis progression

Identification of key signaling pathways and hub genes related to immune infiltration in Kawasaki disease with resistance to intravenous immunoglobulin based on weighted gene co-expression network analysis

Editorial: Oxidative stress in degenerative bone and joint diseases: novel molecular mechanisms and therapeutic potential

Prediction of prognosis and immunotherapy response in breast cancer based on neutrophil extracellular traps-related classification

Casticin as potential anticancer agent: recent advancements in multi-mechanistic approaches

Unsupervised neural network for single cell Multi-omics INTegration (UMINT): an application to health and disease

DPP-4 inhibitors for treating T2DM - hype or hope? an analysis based on the current literature

Identifying a novel cuproptosis-related necroptosis gene subtype-related signature for predicting the prognosis, tumor microenvironment, and immunotherapy of hepatocellular carcinoma

Mass spectrometry imaging as an emerging tool for studying metabolism in human brain organoids