Frontiers in Molecular Biosciences | Molecular Diagnostics and Therapeutics

Original Research

Accepted on 17 Jan 2025

Establishment and Validation of a Recurrent Prediction Model for Glioma: Extrinsic Apoptotic Molecules FADD and CASP8 Are Closely Associated With Glioma Recurrence

in Molecular Diagnostics and Therapeutics

Lei Yang
Li Lanying
YanFang Zhang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1533370

Original Research

Published on 17 Jan 2025

Global trends and emerging insights in BRAF and MEK inhibitor resistance in melanoma: a bibliometric analysis

in Molecular Diagnostics and Therapeutics

Jianhao Bai
Zhongqi Wan
Wanru Zhou
Lijun Wang
Wei Lou
Yao Zhang
Haiying Jin

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1538743

Original Research

Published on 17 Jan 2025

Plasma proteome fingerprint in kidney diseases

in Molecular Diagnostics and Therapeutics

Kirill S. Nikolsky
Arthur T. Kopylov
Valeriya I. Nakhod
Natalia V. Potoldykova
Dmitry V. Enikeev
Tatiana V. Butkova
Liudmila I. Kulikova
Kristina A. Malsagova
Vladimir R. Rudnev
Denis V. Petrovskiy

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1494779

197 views

Retraction

Accepted on 16 Jan 2025

Retraction: ZFP36 Binds With PRC1 to Inhibit Tumor Growth and Increase 5-Fu Chemosensitivity of Hepatocellular Carcinoma

in Molecular Diagnostics and Therapeutics

Frontiers Editorial Office

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1561889

Review

Accepted on 15 Jan 2025

The role of potential oxidative biomarkers in the Prognosis of Intracerebral Hemorrhage and the exploration antioxidants as possible Preventive and Treatment options

in Molecular Diagnostics and Therapeutics

Jiayong Yao
xiaohong dai
xueping yv
lei zheng
jia zheng
binglin kuang
wei teng
weiwei yu
mignyue li
hongtao cao

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1541230

Review

Accepted on 15 Jan 2025

The diagnostic and prognostic significance of HOXC13-AS and its molecular regulatory mechanism in human cancer

in Molecular Diagnostics and Therapeutics

Xiaosi Gu
Xin Hu
Sijia Zhang
Xiaoyu Zhang
Yong Wang
Lianlian Li

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1540048

Original Research

Published on 15 Jan 2025

Predicting patient outcomes with gene-expression biomarkers from colorectal cancer organoids and cell lines

in Molecular Diagnostics and Therapeutics

Alexandra Razumovskaya
Mariia Silkina
Andrey Poloznikov
Timur Kulagin
Maria Raigorodskaya
Nina Gorban
Anna Kudryavtseva
Maria Fedorova
Boris Alekseev
Alexander Tonevitsky

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1531175

250 views

Original Research

Accepted on 14 Jan 2025

Sotorasib resistance triggers epithelial-mesenchymal transition and activates AKT and P38-Mediated Signaling

in Molecular Diagnostics and Therapeutics

Raquel Arantes Megid
Guilherme Gomes Ribeiro
Izabela Natalia Faria Gomes
Ana Carolina Laus
Leticia Ferro Leal
Luciane Sussuchi Da Silva
Abu-Bakr Ariwoola
Josiane Mourão Dias
Rui Manuel Reis
Renato Silva-Oliveira

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1537523

Original Research

Accepted on 13 Jan 2025

Deciphering the Role of miRNA-mRNA Interactions in Cerebral Vasospasm Post Intracranial Hemorrhage

in Molecular Diagnostics and Therapeutics

Xiang Chu
Xiyan Zhu
Honghao Xu
Wenbing Zhao
Debin Guo
Xing Chen
Jinze Wu
Lei Li
Hao Wang
Jun Fei

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1492729

Review

Accepted on 13 Jan 2025

Epigenetic regulation in coronary artery disease: from mechanisms to emerging therapies

in Molecular Diagnostics and Therapeutics

Rui Gao
Meilin Liu
Haoyi Yang
Yuhan Shen
Ni Xia

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1548355

Original Research

Accepted on 09 Jan 2025

Genome-wide CRISPR/Cas9 screening identifies key profibrotic regulators of TGF-β1-induced epithelial-mesenchymal transformation and pulmonary fibrosis

in Molecular Diagnostics and Therapeutics

Chunjiang Tan
Juan Wang
Xiangrong Ye
Kaidirina Kasimu
Ye Li
Feng Luo
Hui Yi
Yifeng Luo

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1507163

104 views

Original Research

Accepted on 09 Jan 2025

Immune Cells in Thyroid Adenoma and Carcinoma: Uncovering a Hidden Value of Assessing Tumor-Host Interplay and its Potential Application in Thyroid Cytopathology

in Molecular Diagnostics and Therapeutics

Iryna Omelianenko
Nazarii Kobyliak
Tetyana Falalyeyeva
Oleksii Seleznov
Pavlina Botsun
Lyudmila Ostapchenko
Oleksandr Korotkyi
Liudmyla Domylivska
Olena Tsyryuk
Galyna Mykhalchyshyn

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1542821

Original Research

Published on 09 Jan 2025

Identification of crucial pathways and genes linked to endoplasmic reticulum stress in PCOS through combined bioinformatic analysis

in Molecular Diagnostics and Therapeutics

Yan Zhang
Xiujuan Chen
Yuan Lin
Xiaoqing Liu
Xiumei Xiong

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1504015

242 views

Mini Review

Published on 08 Jan 2025

Artificial molecular motors in biological applications

in Molecular Diagnostics and Therapeutics

Fuli Fan
Songshen Liu
Yuting Yan
Peng Zhang
Kui Che

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1510619

193 views

Editorial

Accepted on 07 Jan 2025

Oncolytic Virotherapy II

in Molecular Diagnostics and Therapeutics

Ahmed Majeed Al-Shammari
Pier Paolo Piccaluga

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1552643

209 views

Original Research

Accepted on 07 Jan 2025

Homologous Recombination Deficiency (HRD) Test Validation for Patients with High-Grade Advanced Ovarian Cancer

in Molecular Diagnostics and Therapeutics

Angelica Nogueira Rodrigues
Andreza Karine de Barros Almeida Souto
Diocésio Alves Pinto de Andrade
Larissa Müller Gomes
Sandra Satie Koide
Renata de Godoy e Silva
Bruno Batista de Souza
Juliana Doblas Massaro
Andréia Cristina de Melo
Andrea Morais Borges

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1524594

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Articles

Establishment and Validation of a Recurrent Prediction Model for Glioma: Extrinsic Apoptotic Molecules FADD and CASP8 Are Closely Associated With Glioma Recurrence

Global trends and emerging insights in BRAF and MEK inhibitor resistance in melanoma: a bibliometric analysis

Plasma proteome fingerprint in kidney diseases

Retraction: ZFP36 Binds With PRC1 to Inhibit Tumor Growth and Increase 5-Fu Chemosensitivity of Hepatocellular Carcinoma

The role of potential oxidative biomarkers in the Prognosis of Intracerebral Hemorrhage and the exploration antioxidants as possible Preventive and Treatment options

The diagnostic and prognostic significance of HOXC13-AS and its molecular regulatory mechanism in human cancer

Predicting patient outcomes with gene-expression biomarkers from colorectal cancer organoids and cell lines

Sotorasib resistance triggers epithelial-mesenchymal transition and activates AKT and P38-Mediated Signaling

Deciphering the Role of miRNA-mRNA Interactions in Cerebral Vasospasm Post Intracranial Hemorrhage

Epigenetic regulation in coronary artery disease: from mechanisms to emerging therapies

Genome-wide CRISPR/Cas9 screening identifies key profibrotic regulators of TGF-β1-induced epithelial-mesenchymal transformation and pulmonary fibrosis

Immune Cells in Thyroid Adenoma and Carcinoma: Uncovering a Hidden Value of Assessing Tumor-Host Interplay and its Potential Application in Thyroid Cytopathology

Identification of crucial pathways and genes linked to endoplasmic reticulum stress in PCOS through combined bioinformatic analysis

Artificial molecular motors in biological applications

Oncolytic Virotherapy II

Homologous Recombination Deficiency (HRD) Test Validation for Patients with High-Grade Advanced Ovarian Cancer