Frontiers in Molecular Biosciences

Original Research

Published on 28 Sep 2023

AI/ML combined with next-generation sequencing of VHH immune repertoires enables the rapid identification of de novo humanized and sequence-optimized single domain antibodies: a prospective case study

in Biological Modeling and Simulation

Paul Arras
Han Byul Yoo
Lukas Pekar
Thomas Clarke
Lukas Friedrich
Christian Schröter
Jennifer Schanz
Jason Tonillo
Vanessa Siegmund
Achim Doerner

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1249247

10,810 views
7 citations

Review

Published on 28 Sep 2023

Recent insights of obesity-induced gut and adipose tissue dysbiosis in type 2 diabetes

in Molecular Diagnostics and Therapeutics

Debarun Patra
Dipanjan Banerjee
Palla Ramprasad
Soumyajit Roy
Durba Pal
Suman Dasgupta

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1224982

6,895 views
9 citations

Original Research

Published on 27 Sep 2023

LC-MS/MS assisted biomonitoring of ropivacaine and 3-OH-ropivacaine after plane block anesthesia for cardiac device implantation

in Molecular Diagnostics and Therapeutics

Mihaela Butiulca
Lenard Farczadi
Camil Eugen Vari
Silvia Imre
Mihai Pui
Alexandra Lazar

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1243103

1,871 views

Review

Published on 27 Sep 2023

Role of Caveolae family-related proteins in the development of breast cancer

in Protein Biochemistry for Basic and Applied Sciences

Qinyu Han
Shi Qiu
Huiwen Hu
Wenjing Li
Xiangqi Li

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1242426

3,163 views
3 citations

Original Research

Published on 27 Sep 2023

Comparative assessment of Alzheimer’s disease-related biomarkers in plasma and neuron-derived extracellular vesicles: a nested case-control study

in Molecular Diagnostics and Therapeutics

Apostolos Manolopoulos
Francheska Delgado-Peraza
Maja Mustapic
Krishna Ananthu Pucha
Carlos Nogueras-Ortiz
Alexander Daskalopoulos
De’Larrian DeAnté Knight
Jeannie-Marie Leoutsakos
Esther S. Oh
Constantine G. Lyketsos

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1254834

3,485 views
9 citations

Original Research

Published on 27 Sep 2023

Assessment of neutralization susceptibility of Omicron subvariants XBB.1.5 and BQ.1.1 against broad-spectrum neutralizing antibodies through epitopes mapping

in Biological Modeling and Simulation

Masaud Shah
Hyun Goo Woo

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1236617

1,775 views
3 citations

Review

Published on 26 Sep 2023

Recent progress in the effect of ferroptosis of HSCs on the development of liver fibrosis

in Molecular Diagnostics and Therapeutics

Rui Tang
Jing Luo
Xiaoxia Zhu
Pengyu Miao
Hong Tang
Yue Jian
Sibei Ruan
Feng Ling
Mingxi Tang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1258870

3,713 views
4 citations

Original Research

Published on 26 Sep 2023

Molecular basis for cellular retinoic acid-binding protein 1 in modulating CaMKII activation

in Molecular Recognition

Jennifer Nhieu
Michelle C. Miller
Thomas A. Lerdall
Kevin H. Mayo
Li-Na Wei

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1268843

2,309 views
1 citation

Original Research

Published on 25 Sep 2023

Elevated expression of glycolytic genes as a prominent feature of early-onset preeclampsia: insights from integrative transcriptomic analysis

in RNA Networks and Biology

Jie He
Huan Yang
Zheng Liu
Miaomiao Chen
Ying Ye
Yuelan Tao
Shuhong Li
Jie Fang
Jiacheng Xu
Xiafei Wu

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1248771

2,819 views
3 citations

Original Research

Published on 25 Sep 2023

Clethra fimbriata hexanic extract triggers alteration in the energy metabolism in epimastigotes of Trypanosoma cruzi

in Metabolomics

Daniel Pardo-Rodriguez
Paola Lasso
Mary Santamaría-Torres
Mónica P. Cala
Concepción J. Puerta
Jonh Jairo Méndez Arteaga
Jorge Robles
Claudia Cuervo

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1206074

2,281 views
1 citation

Review

Published on 25 Sep 2023

Susceptibility of acute myeloid leukemia cells to ferroptosis and evasion strategies

in Cellular Biochemistry

Hanyun Zhang
Chunjie Sun
Qi Sun
Ye Li
Chao Zhou
Changgang Sun

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1275774

5,355 views
8 citations

Original Research

Published on 22 Sep 2023

Uncovering the immune microenvironment and molecular subtypes of hepatitis B-related liver cirrhosis and developing stable a diagnostic differential model by machine learning and artificial neural networks

in Molecular Diagnostics and Therapeutics

Shengke Zhang
Chenglu Jiang
Lai Jiang
Haiqing Chen
Jinbang Huang
Jieying Zhang
Rui Wang
Hao Chi
Guanhu Yang
Gang Tian

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1275897

4,458 views
13 citations

Original Research

Published on 21 Sep 2023

Impaired cAMP processivity by phosphodiesterase-protein kinase A complexes in acrodysostosis

in Structural Biology

Varun Venkatakrishnan
Abhijeet Ghode
Nikhil K. Tulsian
Ganesh S. Anand

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1202268

2,567 views
2 citations

Review

Published on 21 Sep 2023

Anti-nucleolin aptamer AS1411: an advancing therapeutic

in Molecular Diagnostics and Therapeutics

Alexander Van den Avont
Neelam Sharma-Walia

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1217769

9,290 views
22 citations

Original Research

Published on 21 Sep 2023

Sestrin2 protects against hypoxic nerve injury by regulating mitophagy through SESN2/AMPK pathway

in Cellular Biochemistry

Cunyao Pan
Chongyi Ai
Lanlan Liang
Baoyi Zhang
Qionglin Li
Lingling Pu
Zirou Wang
Weili Liu
Zhaoli Chen
Hui Liu

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1266243

1,999 views
4 citations

Original Research

Published on 21 Sep 2023

Hypoxia and lactate influence VOC production in A549 lung cancer cells

in Metabolomics

Takeshi Furuhashi
Yuki Matsumoto
Ryuga Ishii
Takehito Sugasawa
Shigenori Ota

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1274298

2,498 views

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Articles

AI/ML combined with next-generation sequencing of VHH immune repertoires enables the rapid identification of de novo humanized and sequence-optimized single domain antibodies: a prospective case study

Recent insights of obesity-induced gut and adipose tissue dysbiosis in type 2 diabetes

LC-MS/MS assisted biomonitoring of ropivacaine and 3-OH-ropivacaine after plane block anesthesia for cardiac device implantation

Role of Caveolae family-related proteins in the development of breast cancer

Comparative assessment of Alzheimer’s disease-related biomarkers in plasma and neuron-derived extracellular vesicles: a nested case-control study

Assessment of neutralization susceptibility of Omicron subvariants XBB.1.5 and BQ.1.1 against broad-spectrum neutralizing antibodies through epitopes mapping

Recent progress in the effect of ferroptosis of HSCs on the development of liver fibrosis

Molecular basis for cellular retinoic acid-binding protein 1 in modulating CaMKII activation

Elevated expression of glycolytic genes as a prominent feature of early-onset preeclampsia: insights from integrative transcriptomic analysis

Clethra fimbriata hexanic extract triggers alteration in the energy metabolism in epimastigotes of Trypanosoma cruzi

Susceptibility of acute myeloid leukemia cells to ferroptosis and evasion strategies

Uncovering the immune microenvironment and molecular subtypes of hepatitis B-related liver cirrhosis and developing stable a diagnostic differential model by machine learning and artificial neural networks

Impaired cAMP processivity by phosphodiesterase-protein kinase A complexes in acrodysostosis

Anti-nucleolin aptamer AS1411: an advancing therapeutic

Sestrin2 protects against hypoxic nerve injury by regulating mitophagy through SESN2/AMPK pathway

Hypoxia and lactate influence VOC production in A549 lung cancer cells