Frontiers in Molecular Biosciences

Original Research

Published on 08 Mar 2024

The C-terminal selenenylsulfide of extracellular/non-reduced thioredoxin reductase endows this protein with selectivity to small-molecule electrophilic reagents under oxidative conditions

in Molecular Diagnostics and Therapeutics

Huijun Qin
Chenchen Guo
Bozhen Chen
Hui Huang
Yaping Tian
Liangwei Zhong

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1274850

1,667 views

Review

Published on 07 Mar 2024

Emerging roles of long non-coding RNAs in osteosarcoma

in RNA Networks and Biology

Xun Liao
Rong Wei
Junxiu Zhou
Ke Wu
Jiao Li

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1327459

2,476 views
3 citations

Editorial

Published on 07 Mar 2024

Editorial: Molecular level atomistic and structural insights on biological macromolecules, inhibition, and dynamics studies

in Molecular Biophysics

Chandrabose Selvaraj
Emilia Pedone
Jung-Kul Lee
Sanjeev Kumar Singh

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1362215

1,283 views

Hypothesis and Theory

Published on 07 Mar 2024

Transfer of membrane(s) matter(s)—non-genetic inheritance of (metabolic) phenotypes?

in Lipids, Membranes and Membranous Organelles

Günter A. Müller
Timo D. Müller

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1347397

3,307 views
3 citations

Original Research

Published on 07 Mar 2024

Structural insights into the C-terminus of the histone-lysine N-methyltransferase NSD3 by small-angle X-ray scattering

in Structural Biology

Benny Danilo Belviso
Yunpeng Shen
Benedetta Carrozzini
Masayo Morishita
Eric di Luccio
Rocco Caliandro

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1191246

2,324 views

Original Research

Published on 07 Mar 2024

Proband-independent haplotyping based on NGS-based long-read sequencing for detecting pathogenic variant carrier status in preimplantation genetic testing for monogenic diseases

in Genome Organization and Dynamics

Peiyu Zhang
Xiaomei Zhao
Qinshan Li
Yaqiong Xu
Zengmei Cheng
Lu Yang
Houmei Wang
Yang Tao
Guanyou Huang
Rui Wu

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1329580

2,328 views
3 citations

Original Research

Published on 07 Mar 2024

A GC–MS-based untargeted metabolomics approach for comprehensive metabolic profiling of mycophenolate mofetil-induced toxicity in mice

in Metabolomics

Tongfeng Zhao
Yaxin Zhao
Haotian Chen
Wenxue Sun
Yun Guan

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1332090

2,397 views

Original Research

Published on 07 Mar 2024

Integrating virtual screening, pharmacoinformatics profiling, and molecular dynamics: identification of promising inhibitors targeting 3CLpro of SARS-CoV-2

in Biological Modeling and Simulation

Abeer Mohammad
Ahmed Zheoat
Amjad Oraibi
Ajay Manaithiya
Khalid S. Almaary
Hiba Allah Nafidi
Mohammed Bourhia
Soumaya Kilani-Jaziri
Yousef A. Bin Jardan

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1306179

2,538 views

Editorial

Published on 07 Mar 2024

Editorial: RNA metabolism and DNA stability in the central nervous system (CNS): from aging to neurodegenerative disease

in Genome Organization and Dynamics

Tangliang Li
Wenting Guo
Haibo Wang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1385586

1,368 views

Editorial

Published on 07 Mar 2024

Editorial: New progress in cancer biomarkers and therapy

in Molecular Diagnostics and Therapeutics

Guohui Sun
Chengwei He
Jianhua Wang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1388872

1,414 views

Original Research

Published on 07 Mar 2024

Genetic ablation of Lmp2 increases the susceptibility for impaired cardiac function

in Cellular Biochemistry

Felix A. Trogisch
Franziska Koser
Synje Michel
David A. Liem
Bogdan I. Florea
Markus Hecker
Oliver Drews

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1148948

1,972 views

Original Research

Published on 07 Mar 2024

The structural properties of full-length annexin A11

in Structural Biology

Erika F. Dudas
Mark D. Tully
Tamas Foldes
Geoff Kelly
Gian Gaetano Tartaglia
Annalisa Pastore

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1347741

3,161 views
2 citations

Original Research

Published on 07 Mar 2024

Metabolomic profiling reveals altered phenylalanine metabolism in Parkinson’s disease in an Egyptian cohort

in Metabolomics

Nourhan Shebl
Shaimaa El-Jaafary
Ayman A. Saeed
Passent Elkafrawy
Amr El-Sayed
Samir Shamma
Rasha Elnemr
Jaidaa Mekky
Lobna A. Mohamed
Omar Kittaneh

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1341950

3,379 views
4 citations

Original Research

Published on 07 Mar 2024

Revealing innovative JAK1 and JAK3 inhibitors: a comprehensive study utilizing QSAR, 3D-Pharmacophore screening, molecular docking, molecular dynamics, and MM/GBSA analyses

in Biological Modeling and Simulation

Abdelmoujoud Faris
Ivana Cacciatore
Radwan Alnajjar
Hadni Hanine
Adnane Aouidate
Ramzi A. Mothana
Abdullah R. Alanzi
Menana Elhallaoui

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1348277

4,147 views
4 citations

Mini Review

Published on 07 Mar 2024

The underlying mechanisms of arenaviral entry through matriglycan

in Protein Biochemistry for Basic and Applied Sciences

Michael Katz
Ron Diskin

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1371551

2,527 views

Original Research

Published on 07 Mar 2024

Anion exchange HPLC monitoring of mRNA in vitro transcription reactions to support mRNA manufacturing process development

in Molecular Diagnostics and Therapeutics

Emma N. Welbourne
Kate A. Loveday
Adithya Nair
Ehsan Nourafkan
Jixin Qu
Ken Cook
Zoltán Kis
Mark J. Dickman

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1250833

7,412 views
4 citations

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Articles

The C-terminal selenenylsulfide of extracellular/non-reduced thioredoxin reductase endows this protein with selectivity to small-molecule electrophilic reagents under oxidative conditions

Emerging roles of long non-coding RNAs in osteosarcoma

Editorial: Molecular level atomistic and structural insights on biological macromolecules, inhibition, and dynamics studies

Transfer of membrane(s) matter(s)—non-genetic inheritance of (metabolic) phenotypes?

Structural insights into the C-terminus of the histone-lysine N-methyltransferase NSD3 by small-angle X-ray scattering

Proband-independent haplotyping based on NGS-based long-read sequencing for detecting pathogenic variant carrier status in preimplantation genetic testing for monogenic diseases

A GC–MS-based untargeted metabolomics approach for comprehensive metabolic profiling of mycophenolate mofetil-induced toxicity in mice

Integrating virtual screening, pharmacoinformatics profiling, and molecular dynamics: identification of promising inhibitors targeting 3CLpro of SARS-CoV-2

Editorial: RNA metabolism and DNA stability in the central nervous system (CNS): from aging to neurodegenerative disease

Editorial: New progress in cancer biomarkers and therapy

Genetic ablation of Lmp2 increases the susceptibility for impaired cardiac function

The structural properties of full-length annexin A11

Metabolomic profiling reveals altered phenylalanine metabolism in Parkinson’s disease in an Egyptian cohort

Revealing innovative JAK1 and JAK3 inhibitors: a comprehensive study utilizing QSAR, 3D-Pharmacophore screening, molecular docking, molecular dynamics, and MM/GBSA analyses

The underlying mechanisms of arenaviral entry through matriglycan

Anion exchange HPLC monitoring of mRNA in vitro transcription reactions to support mRNA manufacturing process development