Frontiers in Molecular Biosciences

Original Research

Published on 25 Apr 2024

Inactivation of mitochondrial MUL1 E3 ubiquitin ligase deregulates mitophagy and prevents diet-induced obesity in mice

in Cellular Biochemistry

Lucia Cilenti
Jacopo Di Gregorio
Rohit Mahar
Fei Liu
Camilla T. Ambivero
Muthu Periasamy
Matthew E. Merritt
Antonis S. Zervos

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1397565

3,344 views

Original Research

Published on 25 Apr 2024

Applying GC-MS based serum metabolomic profiling to characterize two traditional Chinese medicine subtypes of diabetic foot gangrene

in Metabolomics

Jiawei Feng
Yuqing Wang
Shengmin Xiang
Yun Luo
Yongcheng Xu
Yuzhen Wang
Yemin Cao
Mingmei Zhou
Cheng Zhao

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1384307

1,399 views

Review

Published on 24 Apr 2024

Modelling esophageal adenocarcinoma and Barrett’s esophagus with patient-derived organoids

in Molecular Diagnostics and Therapeutics

Julia V. Milne
Ebtihal H. Mustafa
Nicholas J. Clemons

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1382070

2,205 views
3 citations

Perspective

Published on 24 Apr 2024

Harnessing inter-kingdom metabolic disparities at the human-fungal interface for novel therapeutic approaches

in Molecular Diagnostics and Therapeutics

Claudio Costantini
Marilena Pariano
Matteo Puccetti
Stefano Giovagnoli
Gioena Pampalone
Mirco Dindo
Barbara Cellini
Luigina Romani

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1386598

1,133 views
1 citation

Correction

Published on 24 Apr 2024

Corrigendum: Evaluation of PIK3CA mutations in advanced ER+/HER2-breast cancer in Portugal – U-PIK Project

in Molecular Diagnostics and Therapeutics

Ana Peixoto
Luís Cirnes
Ana Luísa Carvalho
Maria João Andrade
Maria José Brito
Paula Borralho
Nuno Coimbra
Pedro M. Borralho
Ana Sofia Carneiro
Lisandra Castro

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1298522

814 views

Brief Research Report

Published on 24 Apr 2024

Unique characteristics of the J-domain proximal regions of Hsp70 cochaperone Apj1 in prion propagation/elimination and its overlap with Sis1 function

in Protein Biochemistry for Basic and Applied Sciences

Samantha J. Ganser
Bridget A. McNish
Gillian L. Schwanitz
John L. Delaney
Bridget A. Corpus
Brenda A. Schilke
Anup K. Biswal
Chandan Sahi
Elizabeth A. Craig
Justin K. Hines

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1392608

1,396 views

Correction

Published on 23 Apr 2024

Corrigendum: MicroRNAs regulating tumor immune response in the prediction of the outcome in patients with breast cancer

in Molecular Diagnostics and Therapeutics

Konstantina Thomopoulou
Chara Papadaki
Alexia Monastirioti
George Koronakis
Anastasia Mala
Despoina Kalapanida
Dimitrios Mavroudis
Sofia Agelaki

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1413164

537 views

Original Research

Published on 22 Apr 2024

Analyzing molecular signatures in preeclampsia and fetal growth restriction: Identifying key genes, pathways, and therapeutic targets for preterm birth

in Biological Modeling and Simulation

Muhammad Bilal Azmi
Mushyeda Fatima Nasir
Uzma Asif
Mohsin Kazi
Mohammad N. Uddin
Shamim Akhtar Qureshi

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1384214

2,710 views

Original Research

Published on 22 Apr 2024

Exploring the link between obesity and hypothyroidism in autoimmune thyroid diseases: a metabolic perspective

in Cellular Biochemistry

Mengzhe Jing
Shanshan Shao
Shizhan Ma
Ling Gao
Qian Wang
Meng Zhou

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1379124

1,692 views

Review

Published on 22 Apr 2024

The role of zyxin in signal transduction and its relationship with diseases

in Cellular Biochemistry

Zelan Wu
Daiqin Wu
Qin Zhong
Xue Zou
Zhongjing Liu
Hehua Long
Jing Wei
Xia Li
Fangjie Dai

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1371549

2,060 views
1 citation

Original Research

Published on 18 Apr 2024

Risk factors and metabolomics of mild cognitive impairment in type 2 diabetes mellitus

in Cellular Biochemistry

Tao Luo
Xiao Jiang
Ning Xu
Xinyu Zhao
Xingjie Xie
Xiuwen Xia
XiaoLong Bian
Haixia Liu

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1341290

1,936 views
1 citation

Perspective

Published on 18 Apr 2024

Machine learning approaches to cryoEM density modification differentially affect biomacromolecule and ligand density quality

in Structural Biology

Raymond F. Berkeley
Brian D. Cook
Mark A. Herzik

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1404885

1,840 views
2 citations

Original Research

Published on 18 Apr 2024

Carcinogenic effect of human tumor-derived cell-free filtrates in nude mice

in Cellular Biochemistry

Jorge Berlanga-Acosta
Ernesto Arteaga-Hernandez
Ariana Garcia-Ojalvo
Dayanis Duvergel-Calderin
Marisol Rodriguez-Touseiro
Laura Lopez-Marin
Jose Suarez-Alba
Dasha Fuentes-Morales
Osmany Mendoza-Fuentes
Sheyla Fernández-Puentes

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1361377

1,351 views

Original Research

Published on 18 Apr 2024

Implication of Stm1 in the protection of eIF5A, eEF2 and tRNA through dormant ribosomes

in Structural Biology

Mengtan Du
Xin Li
Wanlin Dong
Fuxing Zeng

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1395220

2,069 views
2 citations

Original Research

Published on 17 Apr 2024

Novel anti-inflammatory effects of the IL-1 receptor in kidney myeloid cells following ischemic AKI

in Molecular Diagnostics and Therapeutics

Yanting Chen
Xiaohan Lu
Raeann L. Whitney
Yu Li
Matthew J. Robson
Randy D. Blakely
Jen-Tsan Chi
Steven D. Crowley
Jamie R. Privratsky

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1366259

2,332 views

Original Research

Published on 17 Apr 2024

Unraveling the evolutionary origin of the P5CS gene: a story of gene fusion and horizontal transfer

in Molecular Evolution

João Pedro Carmo Filgueiras
Marcel Zámocký
Andreia Carina Turchetto-Zolet

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1341684

3,264 views

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Articles

Inactivation of mitochondrial MUL1 E3 ubiquitin ligase deregulates mitophagy and prevents diet-induced obesity in mice

Applying GC-MS based serum metabolomic profiling to characterize two traditional Chinese medicine subtypes of diabetic foot gangrene

Modelling esophageal adenocarcinoma and Barrett’s esophagus with patient-derived organoids

Harnessing inter-kingdom metabolic disparities at the human-fungal interface for novel therapeutic approaches

Corrigendum: Evaluation of PIK3CA mutations in advanced ER+/HER2-breast cancer in Portugal – U-PIK Project

Unique characteristics of the J-domain proximal regions of Hsp70 cochaperone Apj1 in prion propagation/elimination and its overlap with Sis1 function

Corrigendum: MicroRNAs regulating tumor immune response in the prediction of the outcome in patients with breast cancer

Analyzing molecular signatures in preeclampsia and fetal growth restriction: Identifying key genes, pathways, and therapeutic targets for preterm birth

Exploring the link between obesity and hypothyroidism in autoimmune thyroid diseases: a metabolic perspective

The role of zyxin in signal transduction and its relationship with diseases

Risk factors and metabolomics of mild cognitive impairment in type 2 diabetes mellitus

Machine learning approaches to cryoEM density modification differentially affect biomacromolecule and ligand density quality

Carcinogenic effect of human tumor-derived cell-free filtrates in nude mice

Implication of Stm1 in the protection of eIF5A, eEF2 and tRNA through dormant ribosomes

Novel anti-inflammatory effects of the IL-1 receptor in kidney myeloid cells following ischemic AKI

Unraveling the evolutionary origin of the P5CS gene: a story of gene fusion and horizontal transfer