Frontiers in Molecular Biosciences

Brief Research Report

Published on 13 Jan 2025

Metabolomics insights into doxorubicin and 5-fluorouracil combination therapy in triple-negative breast cancer: a xenograft mouse model study

in Metabolomics

Mai M. Hassanein
Yousra A. Hagyousif
Ruba A. Zenati
Hamza M. Al-Hroub
Farman Matloob Khan
Ahmad Y. Abuhelwa
Karem H. Alzoubi
Nelson C. Soares
Waseem El-Huneidi
Eman Abu-Gharbieh

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1517289

232 views

Original Research

Published on 13 Jan 2025

Enhanced intestinal epithelial co-culture model with orbital mechanical stimulation: a proof-of-concept application in food nanotoxicology

in Nanobiotechnology

Mattia Santoni
Giovanni Piccinini
Giovanni Liguori
Maria Roberta Randi
Massimo Baroncini
Liliana Milani
Francesca Danesi

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1529027

195 views

Original Research

Accepted on 09 Jan 2025

Genome-wide CRISPR/Cas9 screening identifies key profibrotic regulators of TGF-β1-induced epithelial-mesenchymal transformation and pulmonary fibrosis

in Molecular Diagnostics and Therapeutics

Chunjiang Tan
Juan Wang
Xiangrong Ye
Kaidirina Kasimu
Ye Li
Feng Luo
Hui Yi
Yifeng Luo

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1507163

104 views

Brief Research Report

Accepted on 09 Jan 2025

Uptake of iron from Ferrous fumarate can be mediated by clathrin-dependent endocytosis in Hutu-80 cells

in Micronutrient Biology

Agata Tarczykowska
Per Malmberg
Nathalie Scheers

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1460565

Original Research

Accepted on 09 Jan 2025

Immune Cells in Thyroid Adenoma and Carcinoma: Uncovering a Hidden Value of Assessing Tumor-Host Interplay and its Potential Application in Thyroid Cytopathology

in Molecular Diagnostics and Therapeutics

Iryna Omelianenko
Nazarii Kobyliak
Tetyana Falalyeyeva
Oleksii Seleznov
Pavlina Botsun
Lyudmila Ostapchenko
Oleksandr Korotkyi
Liudmyla Domylivska
Olena Tsyryuk
Galyna Mykhalchyshyn

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1542821

Original Research

Published on 09 Jan 2025

Identification of crucial pathways and genes linked to endoplasmic reticulum stress in PCOS through combined bioinformatic analysis

in Molecular Diagnostics and Therapeutics

Yan Zhang
Xiujuan Chen
Yuan Lin
Xiaoqing Liu
Xiumei Xiong

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1504015

242 views

Review

Published on 09 Jan 2025

Recent advances of lysine lactylation in prokaryotes and eukaryotes

in Cellular Biochemistry

Wenjuan Zhao
Jiayi Xin
Xin Yu
Zhifang Li
Nan Li

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1510975

302 views

Original Research

Accepted on 08 Jan 2025

PRR13 Expression as a Prognostic Biomarker in Breast Cancer: Correlations with Immune Infiltration and Clinical Outcomes

in Cellular Biochemistry

Mingjing Meng
Jiani Wang
Jiumei Yang
Yangming Zhang
Xusheng Tu
Pan Hu

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1518031

Original Research

Accepted on 08 Jan 2025

Moxibustion Inhibits Inflammation in Monosodium Urate Crystal-induced Gouty Arthritis Model Rats through Metabolomic Regulation

in Metabolomics

Yufeng Xie
Yun Chen
Ting Qin
Jun Li
Zhichun Chang
Yanfang Li
Jianmei Zhang
Mujun Liu
Jianli Wang
Rong Ren

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1433912

Original Research

Published on 08 Jan 2025

Dissecting the biophysical mechanisms of oleate hydratase association with membranes

in Lipids, Membranes and Membranous Organelles

William A. Lathram
Robert J. Neff
Ashley N. Zalla
James D. Brien
Vivekanandan Subramanian
Christopher D. Radka

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1504373

540 views

Mini Review

Published on 08 Jan 2025

Artificial molecular motors in biological applications

in Molecular Diagnostics and Therapeutics

Fuli Fan
Songshen Liu
Yuting Yan
Peng Zhang
Kui Che

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1510619

193 views

Review

Published on 08 Jan 2025

Deciphering olfactory receptor binding mechanisms: a structural and dynamic perspective on olfactory receptors

in Molecular Recognition

Jingtao Wang
Qidong Zhang
Wu Fan
Qingzhao Shi
Jian Mao
Jianping Xie
Guobi Chai
Chenglei Zhang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1498796

254 views

Editorial

Accepted on 07 Jan 2025

Oncolytic Virotherapy II

in Molecular Diagnostics and Therapeutics

Ahmed Majeed Al-Shammari
Pier Paolo Piccaluga

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1552643

209 views

Original Research

Accepted on 07 Jan 2025

Homologous Recombination Deficiency (HRD) Test Validation for Patients with High-Grade Advanced Ovarian Cancer

in Molecular Diagnostics and Therapeutics

Angelica Nogueira Rodrigues
Andreza Karine de Barros Almeida Souto
Diocésio Alves Pinto de Andrade
Larissa Müller Gomes
Sandra Satie Koide
Renata de Godoy e Silva
Bruno Batista de Souza
Juliana Doblas Massaro
Andréia Cristina de Melo
Andrea Morais Borges

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1524594

Original Research

Published on 07 Jan 2025

Irisin reshapes bone metabolic homeostasis to delay age-related osteoporosis by regulating the multipotent differentiation of BMSCs via Wnt pathway

in Cellular Biochemistry

Shangman Xing
Yifan Ma
Bing Song
Min Bai
Kexin Wang
Wenjing Song
Tingting Cao
Chao Guo
Yanying Zhang
Zhandong Wang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1524978

212 views

Editorial

Published on 07 Jan 2025

Editorial: Modelling esophageal adenocarcinoma

in Molecular Diagnostics and Therapeutics

Hisham F. Bahmad
Farah Ballout

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1550595

245 views

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Articles

Metabolomics insights into doxorubicin and 5-fluorouracil combination therapy in triple-negative breast cancer: a xenograft mouse model study

Enhanced intestinal epithelial co-culture model with orbital mechanical stimulation: a proof-of-concept application in food nanotoxicology

Genome-wide CRISPR/Cas9 screening identifies key profibrotic regulators of TGF-β1-induced epithelial-mesenchymal transformation and pulmonary fibrosis

Uptake of iron from Ferrous fumarate can be mediated by clathrin-dependent endocytosis in Hutu-80 cells

Immune Cells in Thyroid Adenoma and Carcinoma: Uncovering a Hidden Value of Assessing Tumor-Host Interplay and its Potential Application in Thyroid Cytopathology

Identification of crucial pathways and genes linked to endoplasmic reticulum stress in PCOS through combined bioinformatic analysis

Recent advances of lysine lactylation in prokaryotes and eukaryotes

PRR13 Expression as a Prognostic Biomarker in Breast Cancer: Correlations with Immune Infiltration and Clinical Outcomes

Moxibustion Inhibits Inflammation in Monosodium Urate Crystal-induced Gouty Arthritis Model Rats through Metabolomic Regulation

Dissecting the biophysical mechanisms of oleate hydratase association with membranes

Artificial molecular motors in biological applications

Deciphering olfactory receptor binding mechanisms: a structural and dynamic perspective on olfactory receptors

Oncolytic Virotherapy II

Homologous Recombination Deficiency (HRD) Test Validation for Patients with High-Grade Advanced Ovarian Cancer

Irisin reshapes bone metabolic homeostasis to delay age-related osteoporosis by regulating the multipotent differentiation of BMSCs via Wnt pathway

Editorial: Modelling esophageal adenocarcinoma