Frontiers in Molecular Biosciences

Original Research

Published on 13 Aug 2024

Computational insights into the mechanisms underlying structural destabilization and recovery in trafficking-deficient hERG mutants

in Biological Modeling and Simulation

Sara AlRawashdeh
Farag E. S. Mosa
Khaled H. Barakat

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1341727

1,130 views

Original Research

Published on 13 Aug 2024

qPCR detection of Mycobacterium leprae DNA in urine samples of leprosy patients using the Rlep gene target

in Molecular Diagnostics and Therapeutics

D. Diana
M. C. Harish

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1435679

1,588 views

Review

Published on 13 Aug 2024

Metabolomics studies in common multifactorial eye disorders: a review of biomarker discovery for age-related macular degeneration, glaucoma, diabetic retinopathy and myopia

in Metabolomics

Gizachew Tilahun Belete
Lei Zhou
King-Kit Li
Pui-Kin So
Chi-Wai Do
Thomas Chuen Lam

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1403844

5,421 views

Original Research

Published on 13 Aug 2024

Artificial intelligence-driven reverse vaccinology for Neisseria gonorrhoeae vaccine: Prioritizing epitope-based candidates

in Molecular Diagnostics and Therapeutics

Ravi Kant
Mohd. Shoaib Khan
Madhu Chopra
Daman Saluja

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1442158

1,501 views

Original Research

Published on 13 Aug 2024

Breathomics for diagnosing tuberculosis in diabetes mellitus patients

in Molecular Diagnostics and Therapeutics

Rong Xu
Ying Zhang
Zhaodong Li
Mingjie He
Hailin Lu
Guizhen Liu
Min Yang
Liang Fu
Xinchun Chen
Guofang Deng

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1436135

1,069 views

Original Research

Published on 12 Aug 2024

Leveraging multi-omics data to infer regulators of mRNA 3’ end processing in glioblastoma

in RNA Networks and Biology

Aleksei Mironov
Lorenzo Franchitti
Shreemoyee Ghosh
Marie-Francoise Ritz
Gregor Hutter
Michele De Bortoli
Mihaela Zavolan

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1363933

1,784 views
1 citation

Original Research

Published on 12 Aug 2024

The downregulation of tight junction proteins and pIgR in the colonic epithelium causes the susceptibility of EpCAM+/− mice to colitis and gut microbiota dysbiosis

in Cellular Biochemistry

Ya Nie
Ting Lin
Yanhong Yang
Wanwan Liu
Qing Hu
Guibin Chen
Li Huang
Huijuan Wu
Cunjie Kong
Zili Lei

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1442611

1,517 views

Review

Published on 12 Aug 2024

Lipids and α-Synuclein: adding further variables to the equation

in Cellular Biochemistry

Jana Schepers
Timo Löser
Christian Behl

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1455817

1,567 views

Editorial

Published on 09 Aug 2024

Editorial: Systems and network approaches to precision medicine and healthcare

in Molecular Diagnostics and Therapeutics

Emma L. Kurnat-Thoma
Cristian Nogales
Sona Vasudevan

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1463962

826 views

Original Research

Published on 09 Aug 2024

Structural modifications and kinetic effects of KRAS interactions with HRAS and NRAS: an in silico comparative analysis of KRAS mutants

in Biological Modeling and Simulation

Isaac Silverman
Michael Gerber
Aaron Shaykevich
Yitzchak Stein
Alexander Siegman
Sanjay Goel
Radhashree Maitra

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1436976

1,602 views

Original Research

Published on 09 Aug 2024

Integrated clinical and metabolomic analysis identifies molecular signatures, biomarkers, and therapeutic targets in primary angle closure glaucoma

in Metabolomics

Vishnu Kannan
Sai Krishna Srimadh Bhagavatham
Rajesh Babu Dandamudi
Haripriya Kunchala
Sivateja Challa
Abdulrahman I. Almansour
Ashish Pargaonkar
Sujith Kumar Pulukool
Anuj Sharma
Venketesh Sivaramakrishnan

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1421030

1,372 views

Original Research

Published on 08 Aug 2024

Revealing the regulation of allergic asthma airway epithelial cell inflammation by STEAP4 targeting MIF through machine learning algorithms and single-cell sequencing analysis

in Molecular Diagnostics and Therapeutics

Lu Qiao
Shi-meng Li
Jun-nian Liu
Hong-lei Duan
Xiao-feng Jiang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1427352

3,335 views
1 citation

Original Research

Published on 08 Aug 2024

A novel mitochondria-related algorithm for predicting the survival outcomes and drug sensitivity of patients with lung adenocarcinoma

in Molecular Diagnostics and Therapeutics

Xianqiao Wu
Hang Chen
Zhen Ge
Binyu Luo
Hanbo Pan
Yiming Shen
Zuorun Xie
Chengwei Zhou

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1397281

963 views

Original Research

Published on 08 Aug 2024

Longitudinal evaluation of manufacturer-specific differences for high-sensitive CRP EQA results

in Molecular Diagnostics and Therapeutics

Nathalie Weiss
Laura Vierbaum
Marcel Kremser
Anne Kaufmann-Stoeck
Silke Kappler
Silvia Ballert
Kathrin Kabrodt
Klaus-Peter Hunfeld
Ingo Schellenberg

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1401405

962 views

Original Research

Published on 07 Aug 2024

Pan-cancer analysis and single-cell analysis reveals FAM110B as a potential target for survival and immunotherapy

in Molecular Diagnostics and Therapeutics

Yuwei Li
Xiaoxi Li
Bihua Wu
Shuangyan Su
Yunpeng Su
Le Guo

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1424104

1,775 views

Original Research

Published on 07 Aug 2024

Discovery of an 8-oxoguanine regulator PCBP1 inhibitor by virtual screening and its synergistic effects with ROS-modulating agents in pancreatic cancer

in Biological Modeling and Simulation

Kexiong Qiao
Chengjie Xu
Chaolei Zhang
Qianqian Wang
Jun Jiang
Zongrong Chen
Liangjing Zhou
Shengnan Jia
Liping Cao

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1441550

1,409 views

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Articles

Computational insights into the mechanisms underlying structural destabilization and recovery in trafficking-deficient hERG mutants

qPCR detection of Mycobacterium leprae DNA in urine samples of leprosy patients using the Rlep gene target

Metabolomics studies in common multifactorial eye disorders: a review of biomarker discovery for age-related macular degeneration, glaucoma, diabetic retinopathy and myopia

Artificial intelligence-driven reverse vaccinology for Neisseria gonorrhoeae vaccine: Prioritizing epitope-based candidates

Breathomics for diagnosing tuberculosis in diabetes mellitus patients

Leveraging multi-omics data to infer regulators of mRNA 3’ end processing in glioblastoma

The downregulation of tight junction proteins and pIgR in the colonic epithelium causes the susceptibility of EpCAM+/− mice to colitis and gut microbiota dysbiosis

Lipids and α-Synuclein: adding further variables to the equation

Editorial: Systems and network approaches to precision medicine and healthcare

Structural modifications and kinetic effects of KRAS interactions with HRAS and NRAS: an in silico comparative analysis of KRAS mutants

Integrated clinical and metabolomic analysis identifies molecular signatures, biomarkers, and therapeutic targets in primary angle closure glaucoma

Revealing the regulation of allergic asthma airway epithelial cell inflammation by STEAP4 targeting MIF through machine learning algorithms and single-cell sequencing analysis

A novel mitochondria-related algorithm for predicting the survival outcomes and drug sensitivity of patients with lung adenocarcinoma

Longitudinal evaluation of manufacturer-specific differences for high-sensitive CRP EQA results

Pan-cancer analysis and single-cell analysis reveals FAM110B as a potential target for survival and immunotherapy

Discovery of an 8-oxoguanine regulator PCBP1 inhibitor by virtual screening and its synergistic effects with ROS-modulating agents in pancreatic cancer