Frontiers in Immunology | Vaccines and Molecular Therapeutics

Original Research

Accepted on 18 Mar 2025

Pan-Vaccinomics Strategy for Developing a Universal Multi-Epitope Vaccine against Endocarditis-Related Pathogens

in Vaccines and Molecular Therapeutics

Peng Chao
Xueqin Zhang
Lei Zhang
Wei Ma
Dong Wang
Aiping Yang
Xiaoyang Chen

Frontiers in Immunology

doi 10.3389/fimmu.2025.1524128

115 views

Original Research

Accepted on 17 Mar 2025

Optimisation of the Cultured ELISpot / Fluorospot technique for the selective investigation of SARS-CoV-2 reactive central memory T-cells

in Vaccines and Molecular Therapeutics

Jack Jerome
Kirsty Wilson
Joshuah Fialho
Georgia Goodchild
Monica Devi Prakash
Charlie Mcleod
Peter C Richmond
Vasso Apostolopoulos
Katie Louise Flanagan
Magdalena Plebanski

Frontiers in Immunology

doi 10.3389/fimmu.2025.1547220

225 views

Original Research

Published on 17 Mar 2025

Evaluation of dual pathogen recognition receptor agonists as adjuvants for respiratory syncytial virus - virus-like particles for pulmonary delivery

in Vaccines and Molecular Therapeutics

Ahmedali S. Mandviwala
Komal Liman
Anke L. W. Huckriede
Vidya A. Arankalle
Harshad P. Patil

Frontiers in Immunology

doi 10.3389/fimmu.2025.1561297

632 views

Original Research

Published on 17 Mar 2025

Mucosal multivalent NDV-based vaccine provides cross-reactive immune responses against SARS-CoV-2 variants in animal models

in Vaccines and Molecular Therapeutics

Irene González-Domínguez
Adam Abdeljawad
Tsoi Ying Lai
Marta Boza
Stephen McCroskery
Nicholas Lemus
Stefan Slamanig
Gagandeep Singh
Prajakta Warang
Temima Yellin

Frontiers in Immunology

doi 10.3389/fimmu.2025.1524477

865 views

Clinical Trial

Published on 17 Mar 2025

Measles-mumps-rubella-vaccination at 6 months of age induces measles-specific T cell responses: a randomized controlled trial

in Vaccines and Molecular Therapeutics

Søren Buus
Dorthe Maria Vittrup
Jonas Damgård Schmidt
Andreas Jensen
Anette Stryhn
Lone Graff Stensballe

Frontiers in Immunology

doi 10.3389/fimmu.2025.1546253

488 views

Brief Research Report

Published on 14 Mar 2025

OligoDOMTM: a T-cell response-enhancing platform applied to cancer immunotherapy

in Vaccines and Molecular Therapeutics

Judith Del Campo
Séverine Valsesia
Elsa Nikly
Roberto Ruiu
Antonella Iacoviello
Elena Quaglino
Federica Cavallo
Dalil Hannani
Emilie Boucher
Florence Nicolas

Frontiers in Immunology

doi 10.3389/fimmu.2025.1549112

669 views

Review

Published on 14 Mar 2025

Insect-specific virus platforms for arbovirus vaccine development

in Vaccines and Molecular Therapeutics

Roy A. Hall
Wilson Nguyen
Alexander A. Khromykh
Andreas Suhrbier

Frontiers in Immunology

doi 10.3389/fimmu.2025.1521104

653 views

Review

Published on 13 Mar 2025

Harnessing immunotherapeutic molecules and diagnostic biomarkers as human-derived adjuvants for MERS-CoV vaccine development

in Vaccines and Molecular Therapeutics

Abdullah R. Alrasheed
Maaweya Awadalla
Hadeel Alnajran
Mohammed H. Alammash
Adil M. Almaqati
Ishtiaq Qadri
Bandar Alosaimi

Frontiers in Immunology

doi 10.3389/fimmu.2025.1538301

392 views

Original Research

Published on 13 Mar 2025

Recombinant protein Ag85B-Rv2660c-MPT70 promotes quality of BCG-induced immune response against Mycobacterium tuberculosis H37Ra

in Vaccines and Molecular Therapeutics

Jiangshan Ouyang
Shaohua Guo
Zhiming Hu
Ting Cao
Jun Mou
Xinxia Gu
Chunxu Huang
Jie Liu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1430808

353 views

Brief Research Report

Published on 12 Mar 2025

The XBB.1.5 mRNA booster vaccine does not significantly increase the percentage of XBB.1.5 mono-reactive T cells

in Vaccines and Molecular Therapeutics

Joel Sop
Alicia Mercado
Alexis Figueroa
Tyler P. Beckey
Caroline C. Traut
Li Zhang
Kellie N. Smith
Joel N. Blankson

Frontiers in Immunology

doi 10.3389/fimmu.2025.1513175

726 views

Original Research

Published on 12 Mar 2025

BCG-derived acellular membrane vesicles elicit antimycobacterial immunity and innate immune memory

in Vaccines and Molecular Therapeutics

Takehiro Yamaguchi
Noriaki Samukawa
Sohkichi Matsumoto
Masayuki Shiota
Masaki Matsumoto
Ryoma Nakao
Satoru Hirayama
Yutaka Yoshida
Akihito Nishiyama
Yuriko Ozeki

Frontiers in Immunology

doi 10.3389/fimmu.2025.1534615

828 views

Review

Published on 07 Mar 2025

Current state of cancer immunity cycle: new strategies and challenges of using precision hydrogels to treat breast cancer

in Vaccines and Molecular Therapeutics

Yingze Zhu
Yanlin Su
Yaxin Guo
Xinyue Wang
Zhuoqi Zhang
Yige Lu
Hang Yang
Hui Pang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1535464

629 views

Review

Published on 07 Mar 2025

Computational tools and data integration to accelerate vaccine development: challenges, opportunities, and future directions

in Vaccines and Molecular Therapeutics

Lindsey N. Anderson
Charles Tapley Hoyt
Jeremy D. Zucker
Andrew D. McNaughton
Jeremy R. Teuton
Klas Karis
Natasha N. Arokium-Christian
Jackson T. Warley
Zachary R. Stromberg
Benjamin M. Gyori

Frontiers in Immunology

doi 10.3389/fimmu.2025.1502484

920 views

Original Research

Published on 07 Mar 2025

Screening and preclinical assessment of novel Mycobacterium tuberculosis recombinant antigens based tuberculin skin testing

in Vaccines and Molecular Therapeutics

Xichao Ou
Eryong Liu
Faiqa Rashid
Shaojun Pei
Guoqin Zhang
Richard Anthony
Ruida Xing
Fei Huang
Hui Xia
Yang Zheng

Frontiers in Immunology

doi 10.3389/fimmu.2025.1498448

790 views

Original Research

Published on 06 Mar 2025

Enhanced T-cell immunity and lower humoral responses following 5-dose SARS-CoV-2 vaccination in patients with inborn errors of immunity compared with healthy controls

in Vaccines and Molecular Therapeutics

Vitor Gabriel Lopes da Silva
Gabriela Justamante Händel Schmitz
Kathleen E. Sullivan
Júlia Barbate
Maria Izabel de Haro Azinar
Carolina Sanchez Aranda
Maria Isabel de Moraes-Pinto

Frontiers in Immunology

doi 10.3389/fimmu.2025.1538453

1,035 views

Correction

Published on 06 Mar 2025

Corrigendum: Mannose-modified erythrocyte membrane-encapsulated chitovanic nanoparticles as a DNA vaccine carrier against reticuloendothelial tissue hyperplasia virus

in Vaccines and Molecular Therapeutics

Yangyang Feng
Feng Tang
Sheng Li
Daiyan Wu
Qianqian Liu
Hangyu Li
Xinnan Zhang
Ziwei Liu
Linzi Zhang
Haibo Feng

Frontiers in Immunology

doi 10.3389/fimmu.2025.1566389

411 views