Frontiers in Immunology | Vaccines and Molecular Therapeutics

Original Research

Accepted on 21 Feb 2025

Protection against N. gonorrhoeae induced by OMV-based Meningococcal Vaccines are associated with cross-species directed humoral and cellular immune responses

in Vaccines and Molecular Therapeutics

Weiyan Zhu
Andreea Waltmann
Marguerite Little
Kristie Lee Connolly
Kathryn A Matthias
Keena S. Thomas
Mary C Gray
Aleksandra E. Sikora
Alison K Criss
Margaret C Bash

Frontiers in Immunology

doi 10.3389/fimmu.2025.1539795

Brief Research Report

Accepted on 21 Feb 2025

The XBB.1.5 mRNA booster vaccine does not significantly increase the percentage of XBB.1.5 monoreactive T cells

in Vaccines and Molecular Therapeutics

Joel Sop
Alicia Mercado
Alexis Figueroa
Tyler Beckey
Caroline Traut
Li Zhang
Kellie N Smith
Joel Blankson

Frontiers in Immunology

doi 10.3389/fimmu.2025.1513175

Brief Research Report

Accepted on 20 Feb 2025

OligoDOM: a T cell response enhancing platform applied to cancer immunotherapy

in Vaccines and Molecular Therapeutics

Judith Del Campo
Séverine Valsesia
Elsa Nikly
Roberto Ruiu
Antonella Iacoviello
Elena Quaglino
Federica Cavallo
Dalil Hannani
Emilie Boucher
Florence Liliane Nicolas

Frontiers in Immunology

doi 10.3389/fimmu.2025.1549112

Review

Accepted on 20 Feb 2025

Harnessing Human-Derived Adjuvants and Immunotherapeutic Molecules for MERS-CoV Vaccine Development

in Vaccines and Molecular Therapeutics

Abdullah R Alrasheed
Dr. Maaweya Awadalla
Hadeel Alnajran
Mohammed H Alammash
Adil M Almaqati
Ishtiaq Qadri
Bandar Alosaimi

Frontiers in Immunology

doi 10.3389/fimmu.2025.1538301

Correction

Accepted on 20 Feb 2025

Corrigendum: [Mannose-modified erythrocyte membrane-encapsulated chitovanic nanoparticles as a DNA vaccine carrier against reticuloendothelial tissue hyperplasia virus]

in Vaccines and Molecular Therapeutics

Feng Yangyang
Feng Tang
Sheng Li
Daiyan Wu
Qianqian Liu
Hangyu Li
Xinnan Zhang
Ziwei Liu
Linzi Zhang
Haibo Feng

Frontiers in Immunology

doi 10.3389/fimmu.2025.1566389

Original Research

Accepted on 20 Feb 2025

BCG-derived acellular membrane vesicles elicit antimycobacterial immunity and innate immune memory

in Vaccines and Molecular Therapeutics

Takehiro Yamaguchi
Noriaki Samukawa
Sohkichi Matsumoto
Masayuki Shiota
Masaki Matsumoto
Ryoma Nakao
Satoru Hirayama
Yutaka Yoshida
Akihito Nishiyama
Yuriko Ozeki

Frontiers in Immunology

doi 10.3389/fimmu.2025.1534615

Clinical Trial

Accepted on 20 Feb 2025

Shared Clinical and Immunologic Features of mRNA Vaccines: Preliminary Results from a Comparative Clinical Study

in Vaccines and Molecular Therapeutics

Robert M Paris
Carlos Fierro
Nelia Sanchez
Daniel Makrinos
Weijie Zhang
Yanbo Sun
Poonam Rohilla
Bethany Girard
Abidemi Adeniji
Anthony DiPiazza

Frontiers in Immunology

doi 10.3389/fimmu.2025.1501275

Original Research

Accepted on 20 Feb 2025

Recombinant protein Ag85B-Rv2660c-MPT70 promotes quality of BCG-induced immune response against Mycobacterium tuberculosis H37Ra

in Vaccines and Molecular Therapeutics

Jiangshan Ouyang
Shaohua Guo
Zhiming Hu
Ting Cao
Jun Mou
Xinxia Gu
Chunxu Huang
Jie Liu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1430808

Review

Accepted on 19 Feb 2025

Current state of cancer immunity cycle: new strategies and challenges of using precision hydrogels to treat breast cancer

in Vaccines and Molecular Therapeutics

Yingze Zhu
Yanlin Su
Yaxin Guo
Xinyue Wang
Yonggui Xiao
Yonggui Xiao
Hang Yang
Hui Pang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1535464

Original Research

Accepted on 19 Feb 2025

Evaluation of safety, immunogenicity, and efficacy of inactivated reverse genetics-based H5N8 highly pathogenic avian influenza virus vaccine with various adjuvants via parenteral and mucosal routes in chickens

in Vaccines and Molecular Therapeutics

Kairat Tabynov
Aidana Kuanyshbek
Leila Yelchibayeva
Kuantay Zharmambet
Zauresh Zhumadilova
Gleb Fomin
Nikolai Petrovsky
Olaitan C Shekoni
Gourapura J Renukaradhya
Kaissar Tabynov

Frontiers in Immunology

doi 10.3389/fimmu.2025.1539492

Clinical Trial

Accepted on 19 Feb 2025

Safety and immunogenicity of GamEvac-Combi, a heterologous rVSVand rAd5-vectored Ebola vaccine: a randomized controlled multicenter clinical trial in the Republic of Guinea and Russia

in Vaccines and Molecular Therapeutics

Denis Yurievich Logunov
Inna Vadimovna Dolzhikova
Mamadou Yero Boiro
Anna Kovyrshina
Alina Shakhmirovna Dzharullaeva
Alina Sergeevna Erokhova
Daria Mikhailovna Grousova
Amir Ildarovich Tukhvatulin
Fatima Magometovna Izhaeva
Yana Vladimirovna Simakova

Frontiers in Immunology

doi 10.3389/fimmu.2025.1487039

Original Research

Published on 19 Feb 2025

The protective role of vitamin D in BNT162b2 vaccine-related acute myocarditis

in Vaccines and Molecular Therapeutics

Hing Wai Tsang
Gilbert T. Chua
Keith Tsz Suen Tung
Rosa Sze Man Wong
Sabrina Siu Ling Tsao
Joshua Sung Chih Wong
Joanna Yuet Ling Tung
Janette Siu Yin Kwok
Jason Cheuk Sing Yam
Godfrey Chi Fung Chan

Frontiers in Immunology

doi 10.3389/fimmu.2025.1501609

1,667 views

Original Research

Published on 18 Feb 2025

Dynamics of spike-specific neutralizing antibodies across five-year emerging SARS-CoV-2 variants of concern reveal conserved epitopes that protect against severe COVID-19

in Vaccines and Molecular Therapeutics

Latifa Zayou
Swayam Prakash
Hawa Vahed
Nisha Rajeswari Dhanushkodi
Afshana Quadiri
Ahmed Belmouden
Zohra Lemkhente
Aziz Chentoufi
Daniel Gil
Jeffrey B. Ulmer

Frontiers in Immunology

doi 10.3389/fimmu.2025.1503954

318 views

Mini Review

Published on 18 Feb 2025

Harnessing adjuvant-induced epigenetic modulation for enhanced immunity in vaccines and cancer therapy

in Vaccines and Molecular Therapeutics

Yasmine Megdiche
Rosângela Salerno-Gonçalves

Frontiers in Immunology

doi 10.3389/fimmu.2025.1547213

176 views

General Commentary

Accepted on 17 Feb 2025

Commentary: Inactivated Rabies Virus Vectored MERS-Coronavirus Vaccine Induces

in Vaccines and Molecular Therapeutics

Shengnan Yang
Hanqi Li
Fuxiao Liu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1549481

158 views

Review

Accepted on 17 Feb 2025

Technological Breakthroughs and Advancements in the Application of mRNA Vaccines: A Comprehensive Exploration and Future Prospects

in Vaccines and Molecular Therapeutics

Zhimeng Wei
Shuai Zhang
Xingya Wang
Ying Xue
Sheng Dang
Jingbo Zhai

Frontiers in Immunology

doi 10.3389/fimmu.2025.1524317

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Articles

Protection against N. gonorrhoeae induced by OMV-based Meningococcal Vaccines are associated with cross-species directed humoral and cellular immune responses

The XBB.1.5 mRNA booster vaccine does not significantly increase the percentage of XBB.1.5 monoreactive T cells

OligoDOM: a T cell response enhancing platform applied to cancer immunotherapy

Harnessing Human-Derived Adjuvants and Immunotherapeutic Molecules for MERS-CoV Vaccine Development

Corrigendum: [Mannose-modified erythrocyte membrane-encapsulated chitovanic nanoparticles as a DNA vaccine carrier against reticuloendothelial tissue hyperplasia virus]

BCG-derived acellular membrane vesicles elicit antimycobacterial immunity and innate immune memory

Shared Clinical and Immunologic Features of mRNA Vaccines: Preliminary Results from a Comparative Clinical Study

Recombinant protein Ag85B-Rv2660c-MPT70 promotes quality of BCG-induced immune response against Mycobacterium tuberculosis H37Ra

Current state of cancer immunity cycle: new strategies and challenges of using precision hydrogels to treat breast cancer

Evaluation of safety, immunogenicity, and efficacy of inactivated reverse genetics-based H5N8 highly pathogenic avian influenza virus vaccine with various adjuvants via parenteral and mucosal routes in chickens

Safety and immunogenicity of GamEvac-Combi, a heterologous rVSVand rAd5-vectored Ebola vaccine: a randomized controlled multicenter clinical trial in the Republic of Guinea and Russia

The protective role of vitamin D in BNT162b2 vaccine-related acute myocarditis

Dynamics of spike-specific neutralizing antibodies across five-year emerging SARS-CoV-2 variants of concern reveal conserved epitopes that protect against severe COVID-19

Harnessing adjuvant-induced epigenetic modulation for enhanced immunity in vaccines and cancer therapy

Commentary: Inactivated Rabies Virus Vectored MERS-Coronavirus Vaccine Induces

Technological Breakthroughs and Advancements in the Application of mRNA Vaccines: A Comprehensive Exploration and Future Prospects