Original Research

Published on 26 Aug 2021

Brd4 Regulates the Homeostasis of CD8+ T-Lymphocytes and Their Proliferation in Response to Antigen Stimulation

in T Cell Biology

Zhilin Peng
Yiwen Zhang
Xiancai Ma
Mo Zhou
Shiyu Wu
Zheng Song
Yaochang Yuan
Yingshi Chen
Yuzhuang Li
Guanwen Wang

Frontiers in Immunology

doi 10.3389/fimmu.2021.728082

5,900 views
4 citations

Review

Published on 26 Aug 2021

Strategies to Overcome Failures in T-Cell Immunotherapies by Targeting PI3K-δ and –γ

in T Cell Biology

Sanjay Chandrasekaran
Christopher Ronald Funk
Troy Kleber
Chrystal M. Paulos
Mala Shanmugam
Edmund K. Waller

Frontiers in Immunology

doi 10.3389/fimmu.2021.718621

9,307 views
21 citations

Review

Published on 20 Aug 2021

Emerging Complexity in CD4+T Lineage Programming and Its Implications in Colorectal Cancer

in T Cell Biology

Daniel DiToro
Rajatava Basu

Frontiers in Immunology

doi 10.3389/fimmu.2021.694833

5,832 views
18 citations

Original Research

Published on 17 Aug 2021

Targeting the Microtubule-Network Rescues CTL Killing Efficiency in Dense 3D Matrices

in T Cell Biology

Renping Zhao
Xiangda Zhou
Essak S. Khan
Dalia Alansary
Kim S. Friedmann
Wenjuan Yang
Eva C. Schwarz
Aránzazu del Campo
Markus Hoth
Bin Qu

Frontiers in Immunology

doi 10.3389/fimmu.2021.729820

5,651 views
15 citations

Original Research

Published on 13 Aug 2021

Binding of Staphylococcal Enterotoxin B (SEB) to B7 Receptors Triggers TCR- and CD28-Mediated Inflammatory Signals in the Absence of MHC Class II Molecules

in T Cell Biology

Martina Kunkl
Carola Amormino
Silvana Caristi
Valentina Tedeschi
Maria Teresa Fiorillo
Revital Levy
Andrey Popugailo
Raymond Kaempfer
Loretta Tuosto

Frontiers in Immunology

doi 10.3389/fimmu.2021.723689

12,565 views
15 citations

Editorial

Published on 13 Aug 2021

Editorial: Thymic Epithelial Cells: New Insights Into the Essential Driving Force of T-Cell Differentiation

in T Cell Biology

Marita Bosticardo
Izumi Ohigashi
Jennifer E. Cowan
Nuno L. Alves

Frontiers in Immunology

doi 10.3389/fimmu.2021.744623

2,496 views
4 citations

Mini Review

Published on 12 Aug 2021

The Clinical Aspect of Adaptor Molecules in T Cell Signaling: Lessons Learnt From Inborn Errors of Immunity

in T Cell Biology

Yael Dinur-Schejter
Irina Zaidman
Hagar Mor-Shaked
Polina Stepensky

Frontiers in Immunology

doi 10.3389/fimmu.2021.701704

3,580 views
14 citations

Original Research

Published on 10 Aug 2021

IgG Immune Complexes Inhibit Naïve T Cell Proliferation and Suppress Effector Function in Cytotoxic T Cells

in T Cell Biology

Wissam Charab
Matthew G. Rosenberger
Haridha Shivram
Justin M. Mirazee
Moses Donkor
Soumya R. Shekhar
Donjeta Gjuka
Kimberly H. Khoo
Jin Eyun Kim
Vishwanath R. Iyer

Frontiers in Immunology

doi 10.3389/fimmu.2021.713704

9,199 views
3 citations

Original Research

Published on 10 Aug 2021

The MS Remyelinating Drug Bexarotene (an RXR Agonist) Promotes Induction of Human Tregs and Suppresses Th17 Differentiation In Vitro

in T Cell Biology

Christopher M. Gaunt
Daniel B. Rainbow
Ruairi J. Mackenzie
Lorna B. Jarvis
Hani S. Mousa
Nicholas Cunniffe
Zoya Georgieva
J. William Brown
Alasdair J. Coles
Joanne L. Jones

Frontiers in Immunology

doi 10.3389/fimmu.2021.712241

4,659 views
11 citations

Original Research

Published on 09 Aug 2021

Distinct Bioenergetic Features of Human Invariant Natural Killer T Cells Enable Retained Functions in Nutrient-Deprived States

in T Cell Biology

Priya Khurana
Chakkapong Burudpakdee
Stephan A. Grupp
Ulf H. Beier
David M. Barrett
Hamid Bassiri

Frontiers in Immunology

doi 10.3389/fimmu.2021.700374

3,864 views
6 citations

Original Research

Published on 09 Aug 2021

Dynamic Network Biomarker of Pre-Exhausted CD8+ T Cells Contributed to T Cell Exhaustion in Colorectal Cancer

in T Cell Biology

Jiaqi Hu
Chongyin Han
Jiayuan Zhong
Huisheng Liu
Rui Liu
Wei Luo
Pei Chen
Fei Ling

Frontiers in Immunology

doi 10.3389/fimmu.2021.691142

11,822 views
27 citations

Original Research

Published on 09 Aug 2021

Single-Cell RNA Sequencing of Peripheral Blood Reveals Immune Cell Signatures in Alzheimer’s Disease

in T Cell Biology

Hui Xu
Jianping Jia

Frontiers in Immunology

doi 10.3389/fimmu.2021.645666

30,426 views
86 citations

Review

Published on 06 Aug 2021

Runx Transcription Factors in T Cells—What Is Beyond Thymic Development?

in T Cell Biology

Svetlana Korinfskaya
Sreeja Parameswaran
Matthew T. Weirauch
Artem Barski

Frontiers in Immunology

doi 10.3389/fimmu.2021.701924

14,958 views
31 citations

Review

Published on 06 Aug 2021

PI3K in T Cell Adhesion and Trafficking

in T Cell Biology

Kristoffer H. Johansen
Dominic P. Golec
Julie H. Thomsen
Pamela L. Schwartzberg
Klaus Okkenhaug

Frontiers in Immunology

doi 10.3389/fimmu.2021.708908

9,877 views
17 citations

Review

Published on 05 Aug 2021

Metabolic Controls on Epigenetic Reprogramming in Regulatory T Cells

in T Cell Biology

Jingli Lu
Yan Liang
Haiyang Meng
Ailing Zhang
Junjie Zhao
Chengliang Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2021.728783

6,156 views
11 citations

Original Research

Published on 05 Aug 2021

BCG Vaccine Derived Peptides Induce SARS-CoV-2 T Cell Cross-Reactivity

in T Cell Biology

Peter J. Eggenhuizen
Boaz H. Ng
Janet Chang
Ashleigh L. Fell
Rachel M. Y. Cheong
Wey Y. Wong
Poh-Yi Gan
Stephen R. Holdsworth
Joshua D. Ooi

Frontiers in Immunology

doi 10.3389/fimmu.2021.692729

18,056 views
40 citations

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Articles

Brd4 Regulates the Homeostasis of CD8+ T-Lymphocytes and Their Proliferation in Response to Antigen Stimulation

Strategies to Overcome Failures in T-Cell Immunotherapies by Targeting PI3K-δ and –γ

Emerging Complexity in CD4+T Lineage Programming and Its Implications in Colorectal Cancer

Targeting the Microtubule-Network Rescues CTL Killing Efficiency in Dense 3D Matrices

Binding of Staphylococcal Enterotoxin B (SEB) to B7 Receptors Triggers TCR- and CD28-Mediated Inflammatory Signals in the Absence of MHC Class II Molecules

Editorial: Thymic Epithelial Cells: New Insights Into the Essential Driving Force of T-Cell Differentiation

The Clinical Aspect of Adaptor Molecules in T Cell Signaling: Lessons Learnt From Inborn Errors of Immunity

IgG Immune Complexes Inhibit Naïve T Cell Proliferation and Suppress Effector Function in Cytotoxic T Cells

The MS Remyelinating Drug Bexarotene (an RXR Agonist) Promotes Induction of Human Tregs and Suppresses Th17 Differentiation In Vitro

Distinct Bioenergetic Features of Human Invariant Natural Killer T Cells Enable Retained Functions in Nutrient-Deprived States

Dynamic Network Biomarker of Pre-Exhausted CD8+ T Cells Contributed to T Cell Exhaustion in Colorectal Cancer

Single-Cell RNA Sequencing of Peripheral Blood Reveals Immune Cell Signatures in Alzheimer’s Disease

Runx Transcription Factors in T Cells—What Is Beyond Thymic Development?

PI3K in T Cell Adhesion and Trafficking

Metabolic Controls on Epigenetic Reprogramming in Regulatory T Cells

BCG Vaccine Derived Peptides Induce SARS-CoV-2 T Cell Cross-Reactivity