Frontiers in Immunology | T Cell Biology

Brief Research Report

Published on 17 Feb 2025

A large-scale database of T-cell receptor beta sequences and binding associations from natural and synthetic exposure to SARS-CoV-2

in T Cell Biology

Sean Nolan
Marissa Vignali
Mark Klinger
Jennifer N. Dines
Ian M. Kaplan
Emily Svejnoha
Tracy Craft
Katie Boland
Mitchell W. Pesesky
Rachel M. Gittelman

Frontiers in Immunology

doi 10.3389/fimmu.2025.1488851

953 views

Original Research

Published on 13 Feb 2025

Modulation of double-negative T cells by Huang-Lian-Jie-Du Decoction attenuates neuroinflammation in ischemic stroke: insights from single-cell transcriptomics

in T Cell Biology

Kai Wang
Zijin Sun
Qi Shao
Zhaoyi Wang
Haojia Zhang
Yuanhua Li
Jingmei Ming
Wenjing Zhang
Tieshan Wang
Yan Zhao

Frontiers in Immunology

doi 10.3389/fimmu.2025.1537277

894 views

Original Research

Published on 11 Feb 2025

Analysis of tumor-infiltrating exhausted T cells highlights IL-6 and PD1 blockade as a combined immunotherapy strategy for non-small cell lung cancer

in T Cell Biology

Lulu Zhang
Xiyuan Guo
Xiaoke Sun
Jue Liao
Qin Liu
Yingchun Ye
Zhihui Yang
Ratchada Cressey
Qing He
Qing Yuan

Frontiers in Immunology

doi 10.3389/fimmu.2025.1486329

1,397 views

Original Research

Published on 07 Feb 2025

Commensal bacteria education history calibrates the naivety and activation threshold of adaptive antiviral immune system

in T Cell Biology

Baohua Li
Zhou Sha
Li Mou
Feng Zhang
Lifeng Jia
Yan Zhu
Yan Guo
Guohong Deng
Haibo Wu
Hong Wei

Frontiers in Immunology

doi 10.3389/fimmu.2025.1519023

918 views

Original Research

Published on 07 Feb 2025

Effects of neutrophil granule proteins on sepsis-associated lymphopenia and their relationship with CD4+ T-cell pyroptosis

in T Cell Biology

Jia-yu Mao
Ya-wen Xie
Xian-li Lei
Jia-hui Zhang
Wei Cheng
Na Cui

Frontiers in Immunology

doi 10.3389/fimmu.2025.1507800

695 views

Original Research

Published on 06 Feb 2025

Unleashing the potential of a low CpG Passer transposon for superior CAR-T cell therapy

in T Cell Biology

Jianyao Zeng
Yan Sun
Yuan Fang
Xiaodie Wang
Qian Huang
Pingjing Zhang
Meiqi Shao
Pei Wang
Jingbo Cheng
Meng Di

Frontiers in Immunology

doi 10.3389/fimmu.2025.1541653

1,177 views

Review

Published on 06 Feb 2025

A comprehensive review of the roles of T-cell immunity in preeclampsia

in T Cell Biology

Xu Peng
Ibeh Chinwe Oluchi-Amaka
Joanne Kwak-Kim
Xiuhua Yang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1476123

1,125 views

Original Research

Published on 28 Jan 2025

Age influences the circulating immune profile in pediatric sepsis

in T Cell Biology

Grace Fisler
Mariana R. Brewer
Omar Yaipen
Clifford S. Deutschman
Matthew D. Taylor

Frontiers in Immunology

doi 10.3389/fimmu.2025.1527142

978 views

Systematic Review

Published on 27 Jan 2025

Systematic review and quantitative meta-analysis of age-dependent human T-lymphocyte homeostasis

in T Cell Biology

Victoria Kulesh
Kirill Peskov
Gabriel Helmlinger
Gennady Bocharov

Frontiers in Immunology

doi 10.3389/fimmu.2025.1475871

1,384 views

Mini Review

Published on 24 Jan 2025

Thymus ad astra, or spaceflight-induced thymic involution

in T Cell Biology

Wataru Muramatsu
Maria Maryanovich
Taishin Akiyama
George S. Karagiannis

Frontiers in Immunology

doi 10.3389/fimmu.2024.1534444

1,786 views

Review

Published on 22 Jan 2025

Tumor cells escape immunosurveillance by hampering LFA-1

in T Cell Biology

Shishir Upadhyay
Lewis Murugu
Lena Svensson

Frontiers in Immunology

doi 10.3389/fimmu.2025.1519841

1,159 views

Original Research

Published on 22 Jan 2025

Identification of circulating Tfh/Th subsets as a biomarker of developed hospital-acquired pneumonia

in T Cell Biology

Yuan Peng
Tao Tao
Ni-Wen Yu
Chenyang Xu
Cheng Chen

Frontiers in Immunology

doi 10.3389/fimmu.2025.1513939

740 views

Original Research

Published on 20 Jan 2025

Annotation and characterization of immunoglobulin loci and CDR3 polymorphism in water buffalo (Bubalus bubalis)

in T Cell Biology

Yunlan Deng
Fengli Wu
Qianqian Li
Lidie Yao
Chengzhi Yang
Long Ma
Xinsheng Yao
Jun Li

Frontiers in Immunology

doi 10.3389/fimmu.2024.1503788

717 views

Original Research

Published on 17 Jan 2025

A self-activated and protective module enhances the preclinical performance of allogeneic anti-CD70 CAR-T cells

in T Cell Biology

Zhao Zhang
Lianfeng Zhao
Tinghui Huang
Zhengliang Chen
Yaoyao Zhao
Junqing Liang
Xudong Ao
Xiaoqiong Jia
Lei Kang
Linghui Kong

Frontiers in Immunology

doi 10.3389/fimmu.2024.1531294

1,946 views

Original Research

Published on 17 Jan 2025

Therapeutic plasma exchange accelerates immune cell recovery in severe COVID-19

in T Cell Biology

Aurelie Guironnet-Paquet
Hind Hamzeh-Cognasse
Frederic Berard
Fabrice Cognasse
Jean Christophe Richard
Hodane Yonis
Mehdi Mezidi
Olivier Desebbe
Bertrand Delannoy
Sophie Demeret

Frontiers in Immunology

doi 10.3389/fimmu.2024.1492672

1,875 views

Original Research

Published on 15 Jan 2025

A conserved element in the first intron of Cd4 has a lineage specific, TCR signal-responsive, canonical enhancer function that matches the timing of cell surface CD4 upregulation required to prevent lineage choice error

in T Cell Biology

Gregory A. Swan
Chika Fujii
Mia E. Guzynski
Sheridan M. Page
Isabelle V. Meyers
Yordan P. Penev
Sejiro Littleton
Adinda Azzahra
Christine Richardson
Sophia D. Sarafova

Frontiers in Immunology

doi 10.3389/fimmu.2024.1469402

1,267 views