Frontiers in Immunology | Systems Immunology

Original Research

Published on 08 Apr 2024

Poly I:C elicits broader and stronger humoral and cellular responses to a Plasmodium vivax circumsporozoite protein malaria vaccine than Alhydrogel in mice

in Systems Immunology

Tiffany B. L. Costa-Gouvea
Katia S. Françoso
Rodolfo F. Marques
Alba Marina Gimenez
Ana C. M. Faria
Leonardo M. Cariste
Mariana R. Dominguez
José Ronnie C. Vasconcelos
Helder I. Nakaya
Eduardo L. V. Silveira

Frontiers in Immunology

doi 10.3389/fimmu.2024.1331474

2,617 views
1 citation

Original Research

Published on 03 Apr 2024

Early B cell transcriptomic markers of measles-specific humoral immunity following a 3rd dose of MMR vaccine

in Systems Immunology

Iana H. Haralambieva
Jun Chen
Huy Quang Quach
Tamar Ratishvili
Nathaniel D. Warner
Inna G. Ovsyannikova
Gregory A. Poland
Richard B. Kennedy

Frontiers in Immunology

doi 10.3389/fimmu.2024.1358477

2,759 views
1 citation

Original Research

Published on 02 Apr 2024

Experimental trials of predicted CD4+ and CD8+ T-cell epitopes of respiratory syncytial virus

in Systems Immunology

Syeda Tahira Qousain Naqvi
Syed Aun Muhammad
Jinlei Guo
Sidra Zafar
Amjad Ali
Larry J. Anderson
Christina A. Rostad
Baogang Bai

Frontiers in Immunology

doi 10.3389/fimmu.2024.1349749

3,280 views

Original Research

Published on 02 Apr 2024

Transcriptome organization of white blood cells through gene co-expression network analysis in a large RNA-seq dataset

in Systems Immunology

Paola Forabosco
Mauro Pala
Francesca Crobu
Maria Antonietta Diana
Mara Marongiu
Roberto Cusano
Andrea Angius
Maristella Steri
Valeria Orrù
David Schlessinger

Frontiers in Immunology

doi 10.3389/fimmu.2024.1350111

2,309 views
1 citation

Review

Published on 02 Apr 2024

New insight into arginine and tryptophan metabolism in macrophage activation during tuberculosis

in Systems Immunology

Kangling Zhang
Abhishek Mishra
Chinnaswamy Jagannath

Frontiers in Immunology

doi 10.3389/fimmu.2024.1363938

6,890 views
10 citations

Original Research

Published on 28 Mar 2024

Bioinformatic validation and machine learning-based exploration of purine metabolism-related gene signatures in the context of immunotherapeutic strategies for nonspecific orbital inflammation

in Systems Immunology

Zixuan Wu
Chi Fang
Yi Hu
Xin Peng
Zheyuan Zhang
Xiaolei Yao
Qinghua Peng

Frontiers in Immunology

doi 10.3389/fimmu.2024.1318316

4,413 views
4 citations

Original Research

Published on 26 Mar 2024

Unraveling IFN-I response dynamics and TNF crosstalk in the pathophysiology of systemic lupus erythematosus

in Systems Immunology

Laura C. Van Eyndhoven
Eleni Chouri
Catarina I. Matos
Aridaman Pandit
Timothy R. D. J. Radstake
Jasper C. A. Broen
Abhyudai Singh
Jurjen Tel

Frontiers in Immunology

doi 10.3389/fimmu.2024.1322814

2,230 views
3 citations

Review

Published on 12 Mar 2024

MHCII-peptide presentation: an assessment of the state-of-the-art prediction methods

in Systems Immunology

Yaqing Yang
Zhonghui Wei
Gabriel Cia
Xixi Song
Fabrizio Pucci
Marianne Rooman
Fuzhong Xue
Qingzhen Hou

Frontiers in Immunology

doi 10.3389/fimmu.2024.1293706

5,646 views
9 citations

Original Research

Published on 08 Mar 2024

Structure-guided engineering and molecular simulations to design a potent monoclonal antibody to target aP2 antigen for adaptive immune response instigation against type 2 diabetes

in Systems Immunology

Abbas Khan
Muhammad Ammar Zahid
Anwar Mohammad
Abdelali Agouni

Frontiers in Immunology

doi 10.3389/fimmu.2024.1357342

2,847 views
2 citations

Original Research

Published on 06 Mar 2024

Exploring potential biomarkers and therapeutic targets in inflammatory bowel disease: insights from a mega-analysis approach

in Systems Immunology

Edia Stemmer
Tamar Zahavi
Maoz Kellerman
Liat Anabel Sinberger
Guy Shrem
Mali Salmon‐Divon

Frontiers in Immunology

doi 10.3389/fimmu.2024.1353402

4,457 views
4 citations

Review

Published on 01 Mar 2024

Interferon lambda in respiratory viral infection: immunomodulatory functions and antiviral effects in epithelium

in Systems Immunology

Yong-Guang Liu
Su-Wei Jin
Shan-Shan Zhang
Tian-Ji Xia
Yong-Hong Liao
Rui-Le Pan
Ming-Zhu Yan
Qi Chang

Frontiers in Immunology

doi 10.3389/fimmu.2024.1338096

5,917 views
3 citations

Original Research

Published on 28 Feb 2024

Investigating the ability of deep learning-based structure prediction to extrapolate and/or enrich the set of antibody CDR canonical forms

in Systems Immunology

Alexander Greenshields-Watson
Brennan Abanades
Charlotte M. Deane

Frontiers in Immunology

doi 10.3389/fimmu.2024.1352703

3,719 views
5 citations

Methods

Published on 26 Feb 2024

Utilizing murine dendritic cell line DC2.4 to evaluate the immunogenicity of subunit vaccines in vitro

in Systems Immunology

Lantian Lu
Wei Yang Kong
Jiahui Zhang
Farrhana Firdaus
James W. Wells
Rachel J. Stephenson
Istvan Toth
Mariusz Skwarczynski
Jazmina L. Gonzalez Cruz

Frontiers in Immunology

doi 10.3389/fimmu.2024.1298721

9,825 views
4 citations

Original Research

Published on 26 Feb 2024

An integrative mechanistic model of thymocyte dynamics

in Systems Immunology

Victoria Kulesh
Kirill Peskov
Gabriel Helmlinger
Gennady Bocharov

Frontiers in Immunology

doi 10.3389/fimmu.2024.1321309

2,240 views
3 citations

Original Research

Published on 23 Feb 2024

CD8+ T and NK cells characterized by upregulation of NPEPPS and ABHD17A are associated with the co-occurrence of type 2 diabetes and coronary artery disease

in Systems Immunology

Chenyu Dai
Damu Wang
Qianqian Tao
Ziyi Li
Peng Zhai
Yingying Wang
Mei Hou
Simin Cheng
Wei Qi
Longyi Zheng

Frontiers in Immunology

doi 10.3389/fimmu.2024.1267963

3,175 views
3 citations

Original Research

Published on 22 Feb 2024

Comprehensive bioinformatics analysis and systems biology approaches to identify the interplay between COVID-19 and pericarditis

in Systems Immunology

Daisong Li
Ruolan Chen
Chao Huang
Guoliang Zhang
Zhaoqing Li
Xiaojian Xu
Banghui Wang
Bing Li
Xian-Ming Chu

Frontiers in Immunology

doi 10.3389/fimmu.2024.1264856

2,361 views
1 citation