Frontiers in Immunology | Systems Immunology

Original Research

Published on 28 Apr 2023

Identification of calcium and integrin-binding protein 1 as a reprogrammed glucose metabolism mediator to restrict immune cell infiltration in the stromal compartment of pancreatic ductal adenocarcinoma

in Systems Immunology

Junrui Ma
Yue Song
Tongtao Zhuang
Hao Yang
Xiaobao Yang
Juanjuan Zheng
Jiajun Luo
Yihan Xia
Xuefeng Fei
David W. Chan

Frontiers in Immunology

doi 10.3389/fimmu.2023.1158964

4,582 views
1 citation

Original Research

Published on 28 Apr 2023

Response to primary chemoradiotherapy of locally advanced oropharyngeal carcinoma is determined by the degree of cytotoxic T cell infiltration within tumor cell aggregates

in Systems Immunology

Maximilian Haist
Justus Kaufmann
Ivan-Maximiliano Kur
Stefanie Zimmer
Stephan Grabbe
Heinz Schmidberger
Andreas Weigert
Arnulf Mayer

Frontiers in Immunology

doi 10.3389/fimmu.2023.1070203

3,136 views
6 citations

Original Research

Published on 27 Apr 2023

Prediction of liver cancer prognosis based on immune cell marker genes

in Systems Immunology

Jianfei Liu
Junjie Qu
Lingling Xu
Chen Qiao
Guiwen Shao
Xin Liu
Hui He
Jian Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2023.1147797

4,217 views
6 citations

Original Research

Published on 26 Apr 2023

Immunological role and prognostic value of the SKA family in pan-cancer analysis

in Systems Immunology

Zhengtian Li
Lanying Huang
Jiachen Li
Wenkang Yang
Weichao Li
Qiuzhong Long
Xinyu Dai
Hongtao Wang
Gang Du

Frontiers in Immunology

doi 10.3389/fimmu.2023.1012999

3,658 views
4 citations

Original Research

Published on 25 Apr 2023

Prediction of HLA genotypes from single-cell transcriptome data

in Systems Immunology

Benjamin D. Solomon
Hong Zheng
Laura W. Dillon
Jason D. Goldman
Christopher S. Hourigan
James R. Heath
Purvesh Khatri

Frontiers in Immunology

doi 10.3389/fimmu.2023.1146826

7,167 views
8 citations

Original Research

Published on 24 Apr 2023

Combination of machine learning-based bulk and single-cell genomics reveals necroptosis-related molecular subtypes and immunological features in autism spectrum disorder

in Systems Immunology

Lichun Liu
Qingxian Fu
Huaili Ding
Hua Jiang
Zhidong Zhan
Yongxing Lai

Frontiers in Immunology

doi 10.3389/fimmu.2023.1139420

4,427 views
8 citations

Original Research

Published on 18 Apr 2023

Performance comparison of TCR-pMHC prediction tools reveals a strong data dependency

in Systems Immunology

Lihua Deng
Cedric Ly
Sina Abdollahi
Yu Zhao
Immo Prinz
Stefan Bonn

Frontiers in Immunology

doi 10.3389/fimmu.2023.1128326

6,386 views
25 citations

Original Research

Published on 14 Apr 2023

Multi-omics analysis reveals a macrophage-related marker gene signature for prognostic prediction, immune landscape, genomic heterogeneity, and drug choices in prostate cancer

in Systems Immunology

Weian Zhu
Jianjie Wu
Jiongduan Huang
Dongming Xiao
Fengao Li
Chenglun Wu
Xiaojuan Li
Hengda Zeng
Jiayu Zheng
Wenjie Lai

Frontiers in Immunology

doi 10.3389/fimmu.2023.1122670

5,546 views
7 citations

Original Research

Published on 06 Apr 2023

Severe COVID-19 and non-COVID-19 severe sepsis converge transcriptionally after a week in the intensive care unit, indicating common disease mechanisms

in Systems Immunology

Andy Y. An
Arjun Baghela
Peter Zhang
Reza Falsafi
Amy H. Lee
Uriel Trahtemberg
Andrew J. Baker
Claudia C. dos Santos
Robert E. W. Hancock

Frontiers in Immunology

doi 10.3389/fimmu.2023.1167917

3,777 views
9 citations

Original Research

Published on 03 Apr 2023

Machine learning for the prediction of all-cause mortality in patients with sepsis-associated acute kidney injury during hospitalization

in Systems Immunology

Hongshan Zhou
Leping Liu
Qinyu Zhao
Xin Jin
Zhangzhe Peng
Wei Wang
Ling Huang
Yanyun Xie
Hui Xu
Lijian Tao

Frontiers in Immunology

doi 10.3389/fimmu.2023.1140755

7,386 views
17 citations

Original Research

Published on 03 Apr 2023

Compartmentalized spatial profiling of the tumor microenvironment in head and neck squamous cell carcinoma identifies immune checkpoint molecules and tumor necrosis factor receptor superfamily members as biomarkers of response to immunotherapy

in Systems Immunology

Habib Sadeghirad
Ning Liu
James Monkman
Ning Ma
Bassem Ben Cheikh
Niyati Jhaveri
Chin Wee Tan
Majid Ebrahimi Warkiani
Mark N. Adams
Quan Nguyen

Frontiers in Immunology

doi 10.3389/fimmu.2023.1135489

10,278 views
25 citations

Original Research

Published on 03 Apr 2023

Distinct subpopulations of DN1 thymocytes exhibit preferential γδ T lineage potential

in Systems Immunology

Seungyoul Oh
Xin Liu
Sara Tomei
Mengxiao Luo
Jarrod P. Skinner
Stuart P. Berzins
Shalin H. Naik
Daniel H. D. Gray
Mark M. W. Chong

Frontiers in Immunology

doi 10.3389/fimmu.2023.1106652

4,733 views
5 citations

Original Research

Published on 30 Mar 2023

Bioinformatics-integrated screening of systemic sclerosis-specific expressed markers to identify therapeutic targets

in Systems Immunology

Jiahui Jin
Yifan Liu
Qinyu Tang
Xin Yan
Miao Jiang
Xu Zhao
Jie Chen
Caixia Jin
Qingjian Ou
Jingjun Zhao

Frontiers in Immunology

doi 10.3389/fimmu.2023.1125183

6,651 views
7 citations

Original Research

Published on 27 Mar 2023

Deciphering the complete human-monkeypox virus interactome: Identifying immune responses and potential drug targets

in Systems Immunology

Raghav Kataria
Simardeep Kaur
Rakesh Kaundal

Frontiers in Immunology

doi 10.3389/fimmu.2023.1116988

12,219 views
14 citations

Methods

Published on 23 Mar 2023

PathwayKO: An integrated platform for deciphering the systems-level signaling pathways

in Systems Immunology

Hannan Ai
Fanmei Meng
Yuncan Ai

Frontiers in Immunology

doi 10.3389/fimmu.2023.1103392

3,298 views

Original Research

Published on 21 Mar 2023

Molecular tracking of insulin resistance and inflammation development on visceral adipose tissue

in Systems Immunology

Antonio Bensussen
José Antonio Torres-Magallanes
Elena Roces de Álvarez-Buylla

Frontiers in Immunology

doi 10.3389/fimmu.2023.1014778

4,470 views
21 citations