Original Research

Published on 29 Jun 2021

Survival and Functional Immune Reconstitution After Haploidentical Stem Cell Transplantation in Atm-Deficient Mice

in Primary Immunodeficiencies

Ruth Pia Duecker
Lucia Gronau
Patrick C. Baer
Stefan Zielen
Ralf Schubert

Frontiers in Immunology

doi 10.3389/fimmu.2021.693897

2,763 views
4 citations

Editorial

Published on 24 Jun 2021

Editorial: Advances in Primary Immunodeficiencies in India

in Primary Immunodeficiencies

Sudhir Gupta
Shobha Sehgal

Frontiers in Immunology

doi 10.3389/fimmu.2021.701335

4,052 views
4 citations

Review

Published on 24 Jun 2021

The Use of Biologic Modifiers as a Bridge to Hematopoietic Cell Transplantation in Primary Immune Regulatory Disorders

in Primary Immunodeficiencies

Danielle E. Arnold
Deepak Chellapandian
Jennifer W. Leiding

Frontiers in Immunology

doi 10.3389/fimmu.2021.692219

3,514 views
13 citations

Case Report

Published on 24 Jun 2021

Case Report: Interleukin-2 Receptor Common Gamma Chain Defect Presented as a Hyper-IgE Syndrome

in Primary Immunodeficiencies

Brahim Belaid
Lydia Lamara Mahammed
Aida Mohand Oussaid
Melanie Migaud
Yasmine Khadri
Jean Laurent Casanova
Anne Puel
Nafissa Ben Halla
Reda Djidjik

Frontiers in Immunology

doi 10.3389/fimmu.2021.696350

9,361 views
5 citations

Original Research

Published on 24 Jun 2021

Normal Numbers of Stem Cell Memory T Cells Despite Strongly Reduced Naive T Cells Support Intact Memory T Cell Compartment in Ataxia Telangiectasia

in Primary Immunodeficiencies

Thomas J. Weitering
Janine E. Melsen
Monique M. van Ostaijen-ten Dam
Corry M. R. Weemaes
Marco W. Schilham
Mirjam van der Burg

Frontiers in Immunology

doi 10.3389/fimmu.2021.686333

4,569 views
7 citations

Original Research

Published on 23 Jun 2021

A Novel Mutation in the NBD Domain of NLRC4 Causes Mild Autoinflammation With Recurrent Urticaria

in Primary Immunodeficiencies

Li Wang
Wen Wen
Mengyue Deng
Yue Li
Gan Sun
Xiaodong Zhao
Xuemei Tang
Huawei Mao

Frontiers in Immunology

doi 10.3389/fimmu.2021.674808

6,008 views
14 citations

Original Research

Published on 17 Jun 2021

A Novel Non-Coding Variant in DCLRE1C Results in Deregulated Splicing and Induces SCID Through the Generation of a Truncated ARTEMIS Protein That Fails to Support V(D)J Recombination and DNA Damage Repair

in Primary Immunodeficiencies

Steven Strubbe
Marieke De Bruyne
Ulrich Pannicke
Elien Beyls
Bart Vandekerckhove
Georges Leclercq
Elfride De Baere
Victoria Bordon
Anne Vral
Klaus Schwarz

Frontiers in Immunology

doi 10.3389/fimmu.2021.674226

5,298 views
3 citations

Case Report

Published on 28 May 2021

AIRE Gene Mutation Presenting at Age 2 Years With Autoimmune Retinopathy and Steroid-Responsive Acute Liver Failure: A Case Report and Literature Review

in Primary Immunodeficiencies

Hirotaka Sakaguchi
Tatsuki Mizuochi
Masatoshi Haruta
Ryuta Takase
Shigeo Yoshida
Yushiro Yamashita
Ryuta Nishikomori

Frontiers in Immunology

doi 10.3389/fimmu.2021.687280

4,422 views
7 citations

Mini Review

Published on 26 May 2021

The Growing Need to Understand Very Early Onset Inflammatory Bowel Disease

in Primary Immunodeficiencies

Hengqi B. Zheng
M. Teresa de la Morena
David L. Suskind

Frontiers in Immunology

doi 10.3389/fimmu.2021.675186

16,354 views
26 citations

Original Research

Published on 24 May 2021

FCGR Genetic Variation in Two Populations From Ecuador Highlands—Extensive Copy-Number Variation, Distinctive Distribution of Functional Polymorphisms, and a Novel, Locally Common, Chimeric FCGR3B/A (CD16B/A) Gene

in Primary Immunodeficiencies

Manuela Moraru
Adriana Perez-Portilla
Karima Al-Akioui Sanz
Alfonso Blazquez-Moreno
Antonio Arnaiz-Villena
Hugh T. Reyburn
Carlos Vilches

Frontiers in Immunology

doi 10.3389/fimmu.2021.615645

5,009 views
4 citations

Original Research

Published on 21 May 2021

Clinical Utility of Whole Exome Sequencing and Targeted Panels for the Identification of Inborn Errors of Immunity in a Resource-Constrained Setting

in Primary Immunodeficiencies

Clair Engelbrecht
Michael Urban
Mardelle Schoeman
Brandon Paarwater
Ansia van Coller
Deepthi Raju Abraham
Helena Cornelissen
Richard Glashoff
Monika Esser
Marlo Möller

Frontiers in Immunology

doi 10.3389/fimmu.2021.665621

6,356 views
18 citations

Review

Published on 18 May 2021

Self-DNA Sensing by cGAS-STING and TLR9 in Autoimmunity: Is the Cytoskeleton in Control?

in Primary Immunodeficiencies

Roberto Amadio
Giulia Maria Piperno
Federica Benvenuti

Frontiers in Immunology

doi 10.3389/fimmu.2021.657344

10,417 views
22 citations

Editorial

Published on 14 May 2021

Editorial: Advances in Primary Immunodeficiency in Central-Eastern Europe

in Primary Immunodeficiencies

Malgorzata Pac
Jean-Laurent Casanova
Ismail Reisli
László Maródi

Frontiers in Immunology

doi 10.3389/fimmu.2021.667727

2,632 views
10 citations

Original Research

Published on 14 May 2021

Patients With Common Variable Immunodeficiency (CVID) Show Higher Gut Bacterial Diversity and Levels of Low-Abundance Genes Than the Healthy Housemates

in Primary Immunodeficiencies

Juraj Bosák
Matej Lexa
Kristýna Fiedorová
Darshak C. Gadara
Lenka Micenková
Zdenek Spacil
Jiří Litzman
Tomáš Freiberger
David Šmajs

Frontiers in Immunology

doi 10.3389/fimmu.2021.671239

6,225 views
19 citations

Case Report

Published on 10 May 2021

Case Report: Hemophagocytic Lymphohistiocytosis and Non-Tuberculous Mycobacteriosis Caused by a Novel GATA2 Variant

in Primary Immunodeficiencies

Thomas Mika
Deepak Vangala
Matthias Eckhardt
Paul La Rosée
Christoph Lange
Kai Lehmberg
Charlotte Wohlschläger
Saskia Biskup
Ilka Fuchs
Jasmin Mann

Frontiers in Immunology

doi 10.3389/fimmu.2021.682934

4,461 views
8 citations

Case Report

Published on 03 May 2021

Case Report: Convalescent Plasma Achieves SARS-CoV-2 Viral Clearance in a Patient With Persistently High Viral Replication Over 8 Weeks Due to Severe Combined Immunodeficiency (SCID) and Graft Failure

in Primary Immunodeficiencies

Verena Keitel
Johannes Georg Bode
Torsten Feldt
Andreas Walker
Lisa Müller
Anselm Kunstein
Caroline Klindt
Alexander Killer
Tina Senff
Jörg Timm

Frontiers in Immunology

doi 10.3389/fimmu.2021.645989

4,045 views
11 citations

Navigation group

Articles

Survival and Functional Immune Reconstitution After Haploidentical Stem Cell Transplantation in Atm-Deficient Mice

Editorial: Advances in Primary Immunodeficiencies in India

The Use of Biologic Modifiers as a Bridge to Hematopoietic Cell Transplantation in Primary Immune Regulatory Disorders

Case Report: Interleukin-2 Receptor Common Gamma Chain Defect Presented as a Hyper-IgE Syndrome

Normal Numbers of Stem Cell Memory T Cells Despite Strongly Reduced Naive T Cells Support Intact Memory T Cell Compartment in Ataxia Telangiectasia

A Novel Mutation in the NBD Domain of NLRC4 Causes Mild Autoinflammation With Recurrent Urticaria

A Novel Non-Coding Variant in DCLRE1C Results in Deregulated Splicing and Induces SCID Through the Generation of a Truncated ARTEMIS Protein That Fails to Support V(D)J Recombination and DNA Damage Repair

AIRE Gene Mutation Presenting at Age 2 Years With Autoimmune Retinopathy and Steroid-Responsive Acute Liver Failure: A Case Report and Literature Review

The Growing Need to Understand Very Early Onset Inflammatory Bowel Disease

FCGR Genetic Variation in Two Populations From Ecuador Highlands—Extensive Copy-Number Variation, Distinctive Distribution of Functional Polymorphisms, and a Novel, Locally Common, Chimeric FCGR3B/A (CD16B/A) Gene

Clinical Utility of Whole Exome Sequencing and Targeted Panels for the Identification of Inborn Errors of Immunity in a Resource-Constrained Setting

Self-DNA Sensing by cGAS-STING and TLR9 in Autoimmunity: Is the Cytoskeleton in Control?

Editorial: Advances in Primary Immunodeficiency in Central-Eastern Europe

Patients With Common Variable Immunodeficiency (CVID) Show Higher Gut Bacterial Diversity and Levels of Low-Abundance Genes Than the Healthy Housemates

Case Report: Hemophagocytic Lymphohistiocytosis and Non-Tuberculous Mycobacteriosis Caused by a Novel GATA2 Variant

Case Report: Convalescent Plasma Achieves SARS-CoV-2 Viral Clearance in a Patient With Persistently High Viral Replication Over 8 Weeks Due to Severe Combined Immunodeficiency (SCID) and Graft Failure