Frontiers in Immunology | Molecular Innate Immunity

Review

Published on 27 Oct 2023

Early innate cell interactions with Mycobacterium tuberculosis in protection and pathology of tuberculosis

in Molecular Innate Immunity

Poornima Sankar
Bibhuti Bhusan Mishra

Frontiers in Immunology

doi 10.3389/fimmu.2023.1260859

9,727 views
21 citations

Clinical Trial

Published on 27 Oct 2023

Recombinant C1 inhibitor in the prevention of severe COVID-19: a randomized, open-label, multi-center phase IIa trial

in Molecular Innate Immunity

Pascal Urwyler
Marina Leimbacher
Panteleimon Charitos
Stephan Moser
Ingmar A. F. M. Heijnen
Marten Trendelenburg
Reto Thoma
Johannes Sumer
Adrián Camacho-Ortiz
Marcelo R. Bacci

Frontiers in Immunology

doi 10.3389/fimmu.2023.1255292

3,060 views
1 citation

Review

Published on 26 Oct 2023

The role and mechanisms of macrophage polarization and hepatocyte pyroptosis in acute liver failure

in Molecular Innate Immunity

Dan Xie
Shi Ouyang

Frontiers in Immunology

doi 10.3389/fimmu.2023.1279264

8,390 views
19 citations

Review

Published on 26 Oct 2023

RIPK1 and RIPK3 inhibitors: potential weapons against inflammation to treat diabetic complications

in Molecular Innate Immunity

Dan Ke
Zhen Zhang
Jieting Liu
Peijian Chen
Yucen Dai
Xinhai Sun
Yanhui Chu
Luxin Li

Frontiers in Immunology

doi 10.3389/fimmu.2023.1274654

5,818 views
6 citations

Original Research

Published on 26 Oct 2023

Multiple TLRs elicit alternative NLRP3 inflammasome activation in primary human monocytes independent of RIPK1 kinase activity

in Molecular Innate Immunity

Sarah Unterberger
Lisa Mullen
Melanie S. Flint
Sandra Sacre

Frontiers in Immunology

doi 10.3389/fimmu.2023.1092799

3,843 views
10 citations

Review

Published on 26 Oct 2023

Chemokines, molecular drivers of thromboinflammation and immunothrombosis

in Molecular Innate Immunity

Julian Leberzammer
Philipp von Hundelshausen

Frontiers in Immunology

doi 10.3389/fimmu.2023.1276353

5,463 views
13 citations

Original Research

Published on 26 Oct 2023

Functional evaluation of complement factor I variants by immunoassays and SDS-PAGE

in Molecular Innate Immunity

Alexandra Gerogianni
Laura M. Baas
Dick J. Sjöström
Nicole C. A. J. van de Kar
Marit Pullen
Siem J. van de Peppel
Per H. Nilsson
Lambertus P. van den Heuvel

Frontiers in Immunology

doi 10.3389/fimmu.2023.1279612

2,350 views
2 citations

Original Research

Published on 25 Oct 2023

Modeling complement activation on human glomerular microvascular endothelial cells

in Molecular Innate Immunity

Kes H. Stevens
Laura M. Baas
Thea J. A. M. van der Velden
Romy N. Bouwmeester
Niels van Dillen
Eiske M. Dorresteijn
Arjan D. van Zuilen
Jack F. M. Wetzels
Marloes A. H. M. Michels
Nicole C. A. J. van de Kar

Frontiers in Immunology

doi 10.3389/fimmu.2023.1206409

3,514 views

Original Research

Published on 25 Oct 2023

Qinhuo Shanggan oral solution resolves acute lung injury by down-regulating TLR4/NF-κB signaling cascade and inhibiting NLRP3 inflammasome activation

in Molecular Innate Immunity

Shun Tang
Yuanjing Liang
Minmin Wang
Jiarong Lei
Yuhui Peng
Qiu Tao
Tianqi Ming
Wenyu Yang
Chuantao Zhang
Jinlin Guo

Frontiers in Immunology

doi 10.3389/fimmu.2023.1285550

3,135 views
7 citations

Review

Published on 25 Oct 2023

The multifaceted role of macrophages in homeostatic and injured skeletal muscle

in Molecular Innate Immunity

Xingyu Wang
Lan Zhou

Frontiers in Immunology

doi 10.3389/fimmu.2023.1274816

6,820 views
15 citations

Original Research

Published on 25 Oct 2023

Tuft cells utilize taste signaling molecules to respond to the pathobiont microbe Ruminococcus gnavus in the proximal colon

in Molecular Innate Immunity

Hao Lei
Defu Yu
Yan-Bo Xue
Yi-Hong Li
Shi-Meng Gong
Yuan-Yuan Peng
Kai-Fang Liu
Damiano Buratto
Yisen Yang
Sai-Sai Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2023.1259521

4,385 views
5 citations

Review

Published on 25 Oct 2023

The role of cGAS-STING signaling in pulmonary fibrosis and its therapeutic potential

in Molecular Innate Immunity

Jing Zhang
Lanlan Zhang
Yutian Chen
Xiaobin Fang
Bo Li
Chunheng Mo

Frontiers in Immunology

doi 10.3389/fimmu.2023.1273248

13,965 views
19 citations

Original Research

Published on 24 Oct 2023

Preferential differential gene expression within the WC1.1+ γδ T cell compartment in cattle naturally infected with Mycobacterium bovis

in Molecular Innate Immunity

Sajad A. Bhat
Mahmoud Elnaggar
Thomas J. Hall
Gillian P. McHugo
Cian Reid
David E. MacHugh
Kieran G. Meade

Frontiers in Immunology

doi 10.3389/fimmu.2023.1265038

4,547 views
5 citations

Original Research

Published on 24 Oct 2023

Dexamethasone impairs the expression of antimicrobial mediators in lipopolysaccharide-activated primary macrophages by inhibiting both expression and function of interferon β

in Molecular Innate Immunity

John D. O’Neil
Oliwia O. Bolimowska
Sally A. Clayton
Tina Tang
Kalbinder K. Daley
Samuel Lara-Reyna
Jordan Warner
Claire S. Martin
Rahul Y. Mahida
Rowan S. Hardy

Frontiers in Immunology

doi 10.3389/fimmu.2023.1190261

4,034 views
3 citations

Review

Published on 23 Oct 2023

Application of toll-like receptors (TLRs) and their agonists in cancer vaccines and immunotherapy

in Molecular Innate Immunity

Samik Chakraborty
Juan Ye
Herui Wang
Mitchell Sun
Yaping Zhang
Xueyu Sang
Zhengping Zhuang

Frontiers in Immunology

doi 10.3389/fimmu.2023.1227833

7,527 views
41 citations

Brief Research Report

Published on 20 Oct 2023

Interactions between Siglec-8 and endogenous sialylated cis ligands restrain cell death induction in human eosinophils and mast cells

in Molecular Innate Immunity

Yun Cao
Clayton H. Rische
Bruce S. Bochner
Jeremy A. O’Sullivan

Frontiers in Immunology

doi 10.3389/fimmu.2023.1283370

3,561 views
3 citations