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Original Research

Published on 09 Jun 2020

Intestinal Delivery of Proinsulin and IL-10 via Lactococcus lactis Combined With Low-Dose Anti-CD3 Restores Tolerance Outside the Window of Acute Type 1 Diabetes Diagnosis

in Immunological Tolerance and Regulation

  • Dana P. Cook
  • João Paulo Monteiro Carvalho Mori Cunha
  • Pieter-Jan Martens
  • Gabriele Sassi
  • Francesca Mancarella
  • Giuliana Ventriglia
  • Guido Sebastiani
  • An-Sofie Vanherwegen
  • Mark A. Atkinson
  • Karolien Van Huynegem
Intestinal Delivery of Proinsulin and IL-10 via Lactococcus lactis Combined With Low-Dose Anti-CD3 Restores Tolerance Outside the Window of Acute Type 1 Diabetes Diagnosis
Frontiers in Immunology
doi 10.3389/fimmu.2020.01103
  • 6,370 views
  • 24 citations