Frontiers in Immunology | Cancer Immunity and Immunotherapy

Original Research

Accepted on 08 Apr 2025

A Comprehensive Pan-Cancer Analysis of LRFN4: Its Potential as a Prognostic Biomarker and Therapeutic Target for Immunotherapy

in Cancer Immunity and Immunotherapy

yinmei yinmei xu
xin wu
peng zhi
Guo Genyu
yankan fu
Lukuan You
siyuan huai
Jianxiong Li

Frontiers in Immunology

doi 10.3389/fimmu.2025.1539076

Original Research

Accepted on 08 Apr 2025

Pan-Cancer Analysis Identifies tRNA Modification Enzyme CTU2 as a Novel Tumor Biomarker and Its Role in Immune Microenvironment

in Cancer Immunity and Immunotherapy

Jiaojiao Wang
Chang Gao
Junyi Zhang
Huahong Luo
Siqi Dai
Jianwei Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1547794

174 views

Case Report

Accepted on 08 Apr 2025

Complete Remission of a High-risk, Locally Advanced Cervical Cancer with Para-aortic Lymph Node Metastases Treated with First-line Tislelizumab plus Bevacizumab Combined with Chemotherapy Followed by Radiotherapy with Maintenance Therapy: a Case Report

in Cancer Immunity and Immunotherapy

Juan Lang
Qianqian Liu
Rong Ji
Miao Qiu
Siben Wang
Qingmeng Liu
Daping Li
Ping Chen
Zhongkui Xiong

Frontiers in Immunology

doi 10.3389/fimmu.2025.1573202

Methods

Accepted on 08 Apr 2025

Engineering safe anti-CD19-CD28ζ CAR T cells with CD8α hinge domain in serum-free media for adoptive immunotherapy

in Cancer Immunity and Immunotherapy

Muthuganesh Muthuvel
Thamizhselvi Ganapathy
Trent Spencer
Sunil S. Raikar
Saravanabhavan Thangavel
Alok Srivastava
Sunil Martin

Frontiers in Immunology

doi 10.3389/fimmu.2025.1545549

124 views

Original Research

Accepted on 08 Apr 2025

Anti-tumor effect and immune-related mechanism study of compound aluminum sulfate injection in transplanted tumor-bearing mice

in Cancer Immunity and Immunotherapy

Zhenwei Shi
Zhifa Xia
Songtao Huang
Zeteng Chen
Fan Yin
Haili Xin
Fenghua Xu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1583275

Original Research

Accepted on 08 Apr 2025

Identification of Prognostic Hub Genes and Functional Role of BAIAP2L2 in Prostate Cancer Progression: A Transcriptomic and Experimental Study

in Cancer Immunity and Immunotherapy

Xiangyang Zhan
Wenkai Wang
Jie Lian
Yichun Li
Jianyi Gu
Dongdong Guo
Dongliang Xu
Guanqun Ju

Frontiers in Immunology

doi 10.3389/fimmu.2025.1543476

Mini Review

Accepted on 08 Apr 2025

Prospects for γδ T cells and chimeric antigen receptor (CAR) γδ T cells in cancer Immunotherapy

in Cancer Immunity and Immunotherapy

Lu Wang
Jiaqi Li
Yaping Xuan
Jinrui Zhang
Xiao Wang
Wei Hu
Lei Xiu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1554541

118 views

Original Research

Accepted on 08 Apr 2025

Serum EMMPRIN/CD147 Promotes the Lung Pre-Metastatic Niche in a D2A1 Mammary Carcinoma Mouse Model

in Cancer Immunity and Immunotherapy

Gabriele Feigelman
Elina Simnovich
Michal Amit Rahat

Frontiers in Immunology

doi 10.3389/fimmu.2025.1568578

Case Report

Accepted on 08 Apr 2025

Abscopal effect in a patient with refractory metastatic hepatocellular carcinoma treated with stereotactic body radiotherapy and PD-1 inhibitor

in Cancer Immunity and Immunotherapy

Pei Shu
Fang Wang
Xin Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1536689

Editorial

Accepted on 08 Apr 2025

Editorial: The Role of Ubiquitination in Disease Development, Progression, and Prognosis

in Cancer Immunity and Immunotherapy

Wenyi Jin
Mingyang Xue

Frontiers in Immunology

doi 10.3389/fimmu.2025.1595755

Original Research

Accepted on 08 Apr 2025

Salmonella LVR01 triggers antagonistic two-armed innate immune memory that impacts on antitumor efficacy

in Cancer Immunity and Immunotherapy

Sofia Chilibroste
Jéssica C. dos Santos
Amy Mónaco
Leo AB Joosten
María Moreno
Jose Alejandro Chabalgoity

Frontiers in Immunology

doi 10.3389/fimmu.2025.1535131

Review

Published on 08 Apr 2025

Crosstalk between exosomes and tumor-associated macrophages in hepatocellular carcinoma: implication for cancer progression and therapy

in Cancer Immunity and Immunotherapy

Ying Xu
Linyue Xu
Qiuyan Chen
Can Zou
Ju Huang
Limei Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1512480

425 views

Systematic Review

Published on 08 Apr 2025

Preoperative glasgow prognostic score was an effective prognostic indicator in patients with biliary tract cancer

in Cancer Immunity and Immunotherapy

Rongqiang Liu
Ling Wang
Jing Ye
Xinyi Li
Wangbin Ma
Ximing Xu
Jia Yu
Weixing Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1560944

229 views

Mini Review

Published on 08 Apr 2025

The role of tumor-associated macrophages in HPV induced cervical cancer

in Cancer Immunity and Immunotherapy

Zeping Chen
Binzhu Zhao

Frontiers in Immunology

doi 10.3389/fimmu.2025.1586806

322 views

Original Research

Published on 08 Apr 2025

Cancer-associated fibroblasts gene signature: a novel approach to survival prediction and immunotherapy guidance in colon cancer

in Cancer Immunity and Immunotherapy

Wenbing Zhang
Chi Yang
Ye Lu
Chenling Tang
Mengyu Zhao
Zhaohui Wang
Jidong Gao
Shuangjiu Hu
Zhihua Chen

Frontiers in Immunology

doi 10.3389/fimmu.2025.1532306

285 views

Original Research

Published on 08 Apr 2025

T-cell receptor dynamics in digestive system cancers: a multi-layer machine learning approach for tumor diagnosis and staging

in Cancer Immunity and Immunotherapy

Changjin Yuan
Bin Wang
Hong Wang
Fang Wang
Xiangze Li
Ya’nan Zhen

Frontiers in Immunology

doi 10.3389/fimmu.2025.1556165

326 views