Frontiers in Immunology | Cancer Immunity and Immunotherapy

Original Research

Published on 12 Mar 2025

Resveratrol alleviates testicular toxicity induced by anti-PD-1 through regulating the NRF2-SLC7A11-GPX4 pathway

in Cancer Immunity and Immunotherapy

Halahati· Tuerxun
Yixin Zhao
Yawen Li
Xingyu Liu
Shuhui Wen
Yuguang Zhao

Frontiers in Immunology

doi 10.3389/fimmu.2025.1529991

1,275 views

Original Research

Published on 12 Mar 2025

Zanubrutinib plus R-CHOP improves the treatment effect of newly diagnosed diffuse large B cell lymphoma with double expression of MYC and BCL-2

in Cancer Immunity and Immunotherapy

Min Zhang
Yingying Wu
Zhipeng Cheng
Lu Zhang
Lin Liu
Fang Liu
Guohui Cui
Linghui Xia
Yu Hu
Heng Mei

Frontiers in Immunology

doi 10.3389/fimmu.2025.1526318

1,206 views

Original Research

Published on 12 Mar 2025

Anti-CD137 agonist antibody–independent and clinically feasible preparation of tumor-infiltrating lymphocytes from soft tissue sarcoma and osteosarcoma

in Cancer Immunity and Immunotherapy

Yining Jin
Zhiliang Jia
Xueqing Xia
Nancy B. Gordon
Joseph A. Ludwig
Neeta Somaiah
Shulin Li

Frontiers in Immunology

doi 10.3389/fimmu.2025.1557006

1,122 views

Case Report

Published on 11 Mar 2025

Case Report: Severe Pneumocystis jirovecii pneumonia following zuberitamab treatment in autoimmune hemolytic anemia

in Cancer Immunity and Immunotherapy

Qian Yang
Peng Ding
Yu-xiang Liu
Kai-chen Zhang
Pei-yang Gao

Frontiers in Immunology

doi 10.3389/fimmu.2025.1546571

574 views

Mini Review

Published on 11 Mar 2025

PARylation-mediated post-transcriptional modifications in cancer immunity and immunotherapy

in Cancer Immunity and Immunotherapy

Kazuya Matsumoto
Yoshinori Matsumoto
Jun Wada

Frontiers in Immunology

doi 10.3389/fimmu.2025.1537615

715 views

Original Research

Published on 11 Mar 2025

Multimodal deep learning for predicting PD-L1 biomarker and clinical immunotherapy outcomes of esophageal cancer

in Cancer Immunity and Immunotherapy

Hui Liu
Yinpu Bai
Zhidong Wang
Shi Yin
Cheng Gong
Bin Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1540013

1,149 views

Original Research

Published on 11 Mar 2025

Single-cell and transcriptome analyses revealed CTHRC1 a potential therapeutic target mediating invasion and tumor microenvironment in TNBC: experimental validation

in Cancer Immunity and Immunotherapy

Hong Wan
Zichen Ling
Yuwei Xie
Han Jiang
Zhifan Ruan
Dashuai Yang
Xiaowei Yang
Jing Pei

Frontiers in Immunology

doi 10.3389/fimmu.2025.1534981

842 views

Original Research

Published on 11 Mar 2025

Differential neuropilin isoform expressions highlight plasticity in macrophages in the heterogenous TME through in-silico profiling

in Cancer Immunity and Immunotherapy

Hyun-Jee Han
Marcos Rubio-Alarcon
Thomas Allen
Sunwoo Lee
Taufiq Rahman

Frontiers in Immunology

doi 10.3389/fimmu.2025.1547330

1,025 views

Systematic Review

Published on 11 Mar 2025

Effectiveness and safety of ICIs for the treatment of advanced CC: a systematic review and meta-analysis

in Cancer Immunity and Immunotherapy

Nurbia Ibibulla
Pengfei Lu
Yiliyaer Nuerrula
Xueqin Hu
Mulati Aihemaiti
Yubo Wang
Hua Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1542850

810 views

Original Research

Published on 11 Mar 2025

Safety and efficacy of PD-1 inhibitors plus tyrosine kinase inhibitors combination therapy in patients with advanced hepatocellular carcinoma combined with hyperbilirubinemia: a retrospective cohort study

in Cancer Immunity and Immunotherapy

Shida Pan
Jianing Wang
Jiahe Tian
Yilin Wang
Siyu Wang
Yingying Yu
Fengyi Li
Yan-Mei Jiao
Yingjuan Shen
Luo Yang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1530477

798 views

Original Research

Published on 11 Mar 2025

Cancer immunotherapy by silencing transcription factor c-Rel using peptide-based nanoparticles

in Cancer Immunity and Immunotherapy

Shuyao Lang
Yuxuan Zhu
Zibin Tan
Yu Zhang
Ruijing Liang
Jian Ren
Ping Li
Fan Pan
Lintao Cai
Youhai H. Chen

Frontiers in Immunology

doi 10.3389/fimmu.2025.1554496

785 views

Case Report

Published on 11 Mar 2025

Pulmonary NUT carcinoma, an elusive and refractory entity, shows transient response to chemotherapeutics and PD-1 inhibitor: a case report and literature review

in Cancer Immunity and Immunotherapy

Guangjian Yang
Runze Liu
Linke Yang
Xue Yang
Xiaoyong Tang
Huiqing Mao

Frontiers in Immunology

doi 10.3389/fimmu.2025.1497124

731 views

Review

Published on 11 Mar 2025

Ubiquitination regulation of mitochondrial homeostasis: a new sight for the treatment of gastrointestinal tumors

in Cancer Immunity and Immunotherapy

Bingqian Huang
Yulin Yang
Jinming Liu
Biao Zhang
Nengming Lin

Frontiers in Immunology

doi 10.3389/fimmu.2025.1533007

783 views

Original Research

Published on 11 Mar 2025

AI-enhanced profiling of phage-display-identified anti-TIM3 and anti-TIGIT novel antibodies

in Cancer Immunity and Immunotherapy

Astrid Musnier
Yannick Corde
Adrien Verdier
Mélanie Cortes
Jean-René Pallandre
Christophe Dumet
Adeline Bouard
AbdelRaouf Keskes
Zakaria Omahdi
Vincent Puard

Frontiers in Immunology

doi 10.3389/fimmu.2025.1499810

1,982 views

Review

Published on 10 Mar 2025

The multifaceted role of phosphodiesterase 4 in tumor: from tumorigenesis to immunotherapy

in Cancer Immunity and Immunotherapy

Huili-li Ren
Shao-hui Zhang
Pei-yuan Li

Frontiers in Immunology

doi 10.3389/fimmu.2025.1528932

1,092 views

Original Research

Published on 10 Mar 2025

Effect of metachronous primary and secondary solid cancers in patients with multiple myeloma: a retrospective study from a single-center

in Cancer Immunity and Immunotherapy

Yunfei Ji
Hujun Li
Huanxin Zhang
Hai Cheng
Ying Wang
Kailin Xu
Zhenyu Li

Frontiers in Immunology

doi 10.3389/fimmu.2025.1516471

904 views