Frontiers in Immunology | Cancer Immunity and Immunotherapy

Original Research

Published on 14 Mar 2025

Efficacy and safety of tocilizumab in managing cytokine release syndrome after CD19 CAR-T therapy for relapsed or refractory B-cell acute lymphoblastic leukemia

in Cancer Immunity and Immunotherapy

Qianyi Zhou
Yuxin An
Xiaomei Zhang
Xia Xiao
Xue Bai
Pengjiang Liu
Yedi Pu
Juanxia Meng
Haibo Zhu
Cuicui Lyu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1530623

979 views

Systematic Review

Published on 14 Mar 2025

Global trends in tumor-associated neutrophil research: a bibliometric and visual analysis

in Cancer Immunity and Immunotherapy

Shaodong Li
Peng Dong
Xueliang Wu
Zhenhua Kang
Guoqiang Yan

Frontiers in Immunology

doi 10.3389/fimmu.2025.1478092

1,105 views

Review

Published on 13 Mar 2025

HER2-positive gastric cancer: from targeted therapy to CAR-T cell therapy

in Cancer Immunity and Immunotherapy

Qiangzu Shao
Junge Deng
Haoran Wu
Zeping Huang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1560280

1,118 views

Review

Published on 13 Mar 2025

Advances in CAR optimization strategies based on CD28

in Cancer Immunity and Immunotherapy

Sijin Li
Yusi Zhou
Hairong Wang
Gexi Qu
Xuan Zhao
Xu Wang
Rui Hou
Zhangchun Guan
Dan Liu
Junnian Zheng

Frontiers in Immunology

doi 10.3389/fimmu.2025.1548772

1,012 views

Original Research

Published on 13 Mar 2025

Study on the efficacy of IFN-γ- and sPD-1-overexpressing BMSCs in enhancing immune effects for the treatment of lung adenocarcinoma

in Cancer Immunity and Immunotherapy

Yahui Xie
Zhen Lv
Yubin Wang
Jin Ma
Xingmin Wei
Guisen Zheng
Jianjun Wu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1554467

1,183 views

Original Research

Published on 13 Mar 2025

Molecular analysis of immune checkpoint inhibitor associated erythema nodosum-like toxicity

in Cancer Immunity and Immunotherapy

Xiaopeng Sun
Margaret L. Axelrod
Paula I. Gonzalez-Ericsson
Violeta Sanchez
Yu Wang
Jonathan L. Curry
Elizabeth J. Phillips
Yaomin Xu
Douglas B. Johnson
Justin M. Balko

Frontiers in Immunology

doi 10.3389/fimmu.2025.1542499

965 views

Original Research

Published on 13 Mar 2025

Fatty acid metabolism-derived prognostic model for lung adenocarcinoma: unraveling the link to survival and immune response

in Cancer Immunity and Immunotherapy

Rui-Ze Wu
Qian-Qian Sun
Yao Fu
Han-Nong Yu
Wei-Yang Liu
Yong-Hui Wu
Han Zhang
Yu-Lin Pan
Xin Rui

Frontiers in Immunology

doi 10.3389/fimmu.2025.1507845

831 views

Original Research

Published on 13 Mar 2025

Developing CAR-T/NK cells that target EphA2 for non-small cell lung cancer treatment

in Cancer Immunity and Immunotherapy

Seok Min Kim
Soo Yun Lee
Seo In Kim
Ji Yeong Bae
Jin Tae Hong
Seona Jo
Ji Hyun Kim
Hyo-Young Chung
Tae-Don Kim

Frontiers in Immunology

doi 10.3389/fimmu.2025.1448438

1,339 views

Original Research

Published on 13 Mar 2025

Mutated DNMT3A creates a public HLADQ- binding neoantigen on acute myeloid leukemia

in Cancer Immunity and Immunotherapy

Dyantha I. van der Lee
Eva M. Argiro
Sebastiaan N. J. Laan
M. Willy Honders
Rob C. M. de Jong
Nadine E. Struckman
J. H. Frederik Falkenburg
Marieke Griffioen

Frontiers in Immunology

doi 10.3389/fimmu.2025.1556121

820 views

Original Research

Published on 13 Mar 2025

A novel tertiary lymphoid structure-associated signature accurately predicts patient prognosis and facilitates the selection of personalized treatment strategies for HNSCC

in Cancer Immunity and Immunotherapy

Jinhao Zhang
Lu Zeng
Guobin Song
Gaoge Peng
Zhezheng Chen
Yamin Yuan
Taowu Chen
Tao Zhong
Shixi Chen
Zhengzhou Luo

Frontiers in Immunology

doi 10.3389/fimmu.2025.1551844

1,215 views

Review

Published on 13 Mar 2025

Prediction, prevention, and precision treatment of immune checkpoint inhibitor neurological toxicity using autoantibodies, cytokines, and microbiota

in Cancer Immunity and Immunotherapy

Alberto Vogrig
Marta Dentoni
Irene Florean
Giulia Cellante
Rossana Domenis
Donatella Iacono
Giacomo Pelizzari
Simone Rossi
Valentina Damato
Martina Fabris

Frontiers in Immunology

doi 10.3389/fimmu.2025.1548897

1,542 views

Mini Review

Published on 12 Mar 2025

Therapeutic strategies for adrenocortical carcinoma: integrating genomic insights, molecular targeting, and immunotherapy

in Cancer Immunity and Immunotherapy

Jing Sun
Jiaxuan Huai
Wenhui Zhang
Tianyu Zhao
Run Shi
Xuanbin Wang
Minglun Li
Xuehua Jiao
Xiqiao Zhou

Frontiers in Immunology

doi 10.3389/fimmu.2025.1545012

919 views

Original Research

Published on 12 Mar 2025

Programmed cell death-related prognostic genes mediate dysregulation of the immune microenvironment in triple-negative breast cancer

in Cancer Immunity and Immunotherapy

Xiaowen Ma
Hui Shan
Zhao Chen
Rongzi Shao
Ning Han

Frontiers in Immunology

doi 10.3389/fimmu.2025.1563630

1,560 views

Original Research

Published on 12 Mar 2025

Prediction model of axillary lymph node status using an automated breast volume ultrasound radiomics nomogram in early breast cancer with negative axillary ultrasound

in Cancer Immunity and Immunotherapy

Qianqing Ma
Junli Wang
Zhengzheng Tu
Jingwen She
Jianhui Zhu
Feng Jiang
Chaoxue Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1460673

720 views

Review

Published on 12 Mar 2025

The application of emerging immunotherapy in the treatment of prostate cancer: progress, dilemma and promise

in Cancer Immunity and Immunotherapy

Jizhong Che
Yuanyuan Liu
Yangyang Liu
Jingheng Song
Hongguo Cui
Dongdong Feng
Aimin Tian
Zhengchao Zhang
Yankai Xu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1544882

956 views

Review

Published on 12 Mar 2025

Understanding the relationship between cuproptosis and the development of hepatocellular carcinoma: implications for targeted therapies

in Cancer Immunity and Immunotherapy

Haixia Zhu
Yamin Zhao
Yaxuan Wang
Guohua Wei
Jibin Liu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1557223

1,045 views