Frontiers in Immunology | Cancer Immunity and Immunotherapy

Review

Accepted on 21 Mar 2025

The Role of Macrophage Polarization in Ovarian Cancer: From Molecular Mechanism to Therapeutic Potentials

in Cancer Immunity and Immunotherapy

Chenchen Xu
Jiyu Chen
Mi Tan
Qingqing Tan

Frontiers in Immunology

doi 10.3389/fimmu.2025.1543096

113 views

Original Research

Accepted on 21 Mar 2025

Revolutionizing Cervical Cancer Treatment: Single-Cell Sequencing of TSPAN1+ Tumor EPCs and Immune Checkpoints to Assess Drug Sensitivity and Optimize Therapy

in Cancer Immunity and Immunotherapy

Yumeng Li
Zhiheng Lin
Guangyao Lin
Zhijie Zhao
Xiahou Zhikai
Pingping Cai

Frontiers in Immunology

doi 10.3389/fimmu.2025.1574174

Original Research

Accepted on 21 Mar 2025

In vivo RNAi screen and validation reveals Ngp, Hba-a1, and S100a8 as novel inhibitory targets on T lymphocytes in liver cancer

in Cancer Immunity and Immunotherapy

Inga Hochnadel
Lisa Hoenicke
Nataliia Petriv
Huizhen Suo
Lothar Groebe
Chantal Olijnik
Nina Bondarenko
Juan Carlos López Alfonso
Michael Jarek
Ruibing Shi

Frontiers in Immunology

doi 10.3389/fimmu.2025.1549229

172 views

Mini Review

Published on 21 Mar 2025

Targeting tumor-associated macrophages in colon cancer: mechanisms and therapeutic strategies

in Cancer Immunity and Immunotherapy

Jianqin Xiang
Jian Wang
Huihui Xiao
Chengchen Huang
Chunrong Wu
Lin Zhang
Chenyuan Qian
Debing Xiang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1573917

998 views

Mini Review

Published on 21 Mar 2025

Organoid models of ovarian cancer: resolving immune mechanisms of metabolic reprogramming and drug resistance

in Cancer Immunity and Immunotherapy

Lanyue Zhang
Jiangnan Zhao
Chunyu Su
Jianxi Wu
Lai Jiang
Hao Chi
Qin Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1573686

1,476 views

Review

Published on 21 Mar 2025

Molecular biology of the deadliest cancer – glioblastoma: what do we know?

in Cancer Immunity and Immunotherapy

Aly Ismailov
Aldo Spallone
Alexey Belogurov
Alan Herbert
Maria Poptsova

Frontiers in Immunology

doi 10.3389/fimmu.2025.1530305

1,138 views

Original Research

Published on 21 Mar 2025

Multi-targeted, NOT gated CAR-T cells as a strategy to protect normal lineages for blood cancer therapy

in Cancer Immunity and Immunotherapy

Breanna DiAndreth
Pavlo A. Nesterenko
Aaron G. Winters
Aaron D. Flynn
Claudia A. Jette
Vasantika Suryawanshi
Sanam Shafaattalab
Sara Martire
Mark Daris
Elizabeth Moore

Frontiers in Immunology

doi 10.3389/fimmu.2025.1493329

1,529 views

Review

Published on 21 Mar 2025

Characterizing macrophage diversity in colorectal malignancies through single-cell genomics

in Cancer Immunity and Immunotherapy

Tingshuo Zhao
Yinyi Luo
Yuanjie Sun
Zhigang Wei

Frontiers in Immunology

doi 10.3389/fimmu.2025.1526668

977 views

Original Research

Published on 21 Mar 2025

Circadian rhythm related genes identified through tumorigenesis and immune infiltration-guided strategies as predictors of prognosis, immunotherapy response, and candidate drugs in skin cutaneous malignant melanoma

in Cancer Immunity and Immunotherapy

Chengling Liu
Xingchen Liu
Pengjuan Cao
Haiming Xin
Xin Li
Sailing Zhu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1513750

1,022 views

Mini Review

Published on 21 Mar 2025

The distinct roles of IL-37 and IL-38 in non-small cell lung carcinoma and their clinical implications

in Cancer Immunity and Immunotherapy

Jiwei Zhang
Steven G. Wise
Shunqing Zuo
Shisan Bao
Xufeng Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1564357

1,060 views

Original Research

Published on 21 Mar 2025

Altered immune cell profiles in blood of mature/peripheral T-cell leukemia/lymphoma patients: an EuroFlow study

in Cancer Immunity and Immunotherapy

F. Javier Morán-Plata
Noemí Muñoz-García
Susana Barrena
Ana Yeguas
Ana Balanzategui
Sonia Carretero-Domínguez
Quentin Lécrevisse
María González-González
Sheila Mateos
Lidia Silos

Frontiers in Immunology

doi 10.3389/fimmu.2025.1561152

767 views

Original Research

Published on 21 Mar 2025

Metabolic reprogramming shapes the immune microenvironment in pancreatic adenocarcinoma: prognostic implications and therapeutic targets

in Cancer Immunity and Immunotherapy

Weihua Song
Yabin Yu
Siqi Wang
Zhengyi Cui
Qiusi Zhu
Wangrui Liu
Shiyin Wei
Jiachang Chi

Frontiers in Immunology

doi 10.3389/fimmu.2025.1555287

1,444 views

Case Report

Published on 21 Mar 2025

Case Report: Anti-Yo antibody mediated paraneoplastic cerebellar degeneration in a patient with squamous cell lung carcinoma

in Cancer Immunity and Immunotherapy

Chen-Hao Yang
Yan Xu
Si-Yuan Fan

Frontiers in Immunology

doi 10.3389/fimmu.2025.1558867

870 views

Review

Published on 21 Mar 2025

Role of long non-coding RNAs in the regulation of ferroptosis in tumors

in Cancer Immunity and Immunotherapy

Ying Ju
Yuanhao Lv
Xu Liu
Jing Lu
Yashen Shi
Huimin Guo
Siguang Xu
Jiaqi Tian
Jun Yang
Jiateng Zhong

Frontiers in Immunology

doi 10.3389/fimmu.2025.1568567

870 views

Systematic Review

Published on 21 Mar 2025

Assessing the impact of probiotics on immunotherapy effectiveness and antibiotic-mediated resistance in cancer: a systematic review and meta-analysis

in Cancer Immunity and Immunotherapy

Shuya Zhao
Zian Lu
Fangmin Zhao
Shihuan Tang
Lishan Zhang
Cuiling Feng

Frontiers in Immunology

doi 10.3389/fimmu.2025.1538969

1,082 views

Review

Published on 21 Mar 2025

New player in CAR-T manufacture field: comparison of umbilical cord to peripheral blood strategies

in Cancer Immunity and Immunotherapy

Karolina Rassek
Jan Misiak
Tomasz Ołdak
Natalia Rozwadowska
Grzegorz Basak
Tomasz Kolanowski

Frontiers in Immunology

doi 10.3389/fimmu.2025.1561174

1,507 views