Frontiers in Immunology | Cancer Immunity and Immunotherapy

Original Research

Published on 26 Mar 2025

Prognostic and immunotherapeutic potential of disulfidptosis-associated signature in pancreatic cancer

in Cancer Immunity and Immunotherapy

Ran Cui
Gaoming Wang
Renhao Hu
Yongkun Wang
Huiling Mu
Yanxiang Song
Bo Chen
Xiaohua Jiang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1568976

892 views

Systematic Review

Published on 26 Mar 2025

Efficacy and safety of PD-1/PD-L1 inhibitors as first-line treatment for esophageal squamous cell carcinoma: a systematic review and meta-analysis

in Cancer Immunity and Immunotherapy

Wei Ren
Hanyu Zhang
Yixin Li
Wu Sun
Hexiang Peng
Huangda Guo
Tianjiao Hou
Mengying Wang
Zhendong Hu
Tao Wu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1563300

1,317 views

Original Research

Published on 26 Mar 2025

Exploring the possible mechanism of low-dose naloxone exposure improving the immune microenvironment of gastric cancer tumors

in Cancer Immunity and Immunotherapy

Xiangzhen Min
Yan Ma
Mingyue Lv
Xiaoxi Li
Renjun Lv
Xiaoyong Zhao
Yufang Leng

Frontiers in Immunology

doi 10.3389/fimmu.2025.1524930

957 views

Review

Published on 26 Mar 2025

Regulation of immunogenic cell death and potential applications in cancer therapy

in Cancer Immunity and Immunotherapy

Kun Fang
Shuai Yuan
Xue Zhang
Jingdong Zhang
Shu-lan Sun
Xiaoxi Li

Frontiers in Immunology

doi 10.3389/fimmu.2025.1571212

873 views

Systematic Review

Published on 26 Mar 2025

The efficacy and safety of PD-1/PD-L1 inhibitors in combination with chemotherapy as a first-line treatment for unresectable, locally advanced, HER2-negative gastric or gastroesophageal junction cancer: a meta-analysis of randomized controlled trials

in Cancer Immunity and Immunotherapy

Wenji Pu
Shasha Li
Jinliang Zhang
Jijie Huang
Jishi Li
Yong Jiang
Zhiyuan Xu
Fan Yi
Yuling Lan
Qin Xiao

Frontiers in Immunology

doi 10.3389/fimmu.2025.1566939

2,127 views

Review

Published on 26 Mar 2025

Impact of lactate on immune cell function in the tumor microenvironment: mechanisms and therapeutic perspectives

in Cancer Immunity and Immunotherapy

Xuan-Yu Gu
Jia-Li Yang
Rui Lai
Zheng-Jun Zhou
Dan Tang
Long Hu
Li-Jin Zhao

Frontiers in Immunology

doi 10.3389/fimmu.2025.1563303

1,185 views

Review

Published on 26 Mar 2025

The solid tumor microenvironment and related targeting strategies: a concise review

in Cancer Immunity and Immunotherapy

Yingliang Wang
Huimin Zhou
Shuguang Ju
Xiangjun Dong
Chuansheng Zheng

Frontiers in Immunology

doi 10.3389/fimmu.2025.1563858

826 views

Original Research

Accepted on 25 Mar 2025

The bispecific antibody targeting VISTA and PD-L1 shows enhanced tumor inhibitory activity in pancreatic, endometrial and breast cancers compared to mono-and combination immune checkpoint blockade

in Cancer Immunity and Immunotherapy

Przemysław Bielski
Jan Barczyński
Michał Mikitiuk
Maja Myrcha
Urszula Tyrcha
Aleksandra Hec-Gałązka
Tad A. Holak
Tomasz Sitar

Frontiers in Immunology

doi 10.3389/fimmu.2025.1486799

221 views

Original Research

Accepted on 25 Mar 2025

Diagnostic value of exosome-derived lncRNA PITPNA-AS1 in lung cancer

in Cancer Immunity and Immunotherapy

MuJin Chen
Xiaohui Feng
Chengchen Liu
Yan Huang
Lijuan Su
Xiaofeng Li
Jinfeng Zhu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1539557

144 views

Review

Published on 25 Mar 2025

The conflicting role highlights the complexity of GSDMs in cancer

in Cancer Immunity and Immunotherapy

Sijia He
Qian Huang
Jin Cheng

Frontiers in Immunology

doi 10.3389/fimmu.2025.1531695

693 views

Review

Published on 25 Mar 2025

CTHRC1: a key player in colorectal cancer progression and immune evasion

in Cancer Immunity and Immunotherapy

Qingjie Chen
Haohao Wang
Qinghua Liu
Changjiang Luo

Frontiers in Immunology

doi 10.3389/fimmu.2025.1579661

1,164 views

General Commentary

Published on 25 Mar 2025

Commentary: Disulfidptosis-related gene signatures as prognostic biomarkers and predictors of immunotherapy response in HNSCC

in Cancer Immunity and Immunotherapy

Jihao Xue
Cheng Xue
Qijia Yin
Ligang Chen
Ming Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1575090

525 views

Original Research

Published on 25 Mar 2025

Prediction model of gastrointestinal tumor malignancy based on coagulation indicators such as TEG and neural networks

in Cancer Immunity and Immunotherapy

Fulong Yu
Chudi Sun
Liang Li
Xiaoyu Yu
Shumin Shen
Hao Qiang
Song Wang
Xianghua Li
Lin Zhang
Zhining Liu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1507773

643 views

Review

Accepted on 24 Mar 2025

Eph/Ephrin-Mediated Immune Modulation: A Potential Therapeutic Target for Skin Cancer

in Cancer Immunity and Immunotherapy

Konstantinos Giannopoulos
Ioannis Karikis
Chad Byrd
Georgios Sanidas
Nora Wolff
Maria Triantafyllou
Gabriele Simonti
Robinson Vidva
Ioannis Koutroulis
Stamos Theocharis

Frontiers in Immunology

doi 10.3389/fimmu.2025.1539567

137 views

Original Research

Accepted on 24 Mar 2025

European Survey on CAR T-Cell Analytical Methods from Apheresis to Post-Infusion Immunomonitoring

in Cancer Immunity and Immunotherapy

BIAGIO DE ANGELIS
Maria Luisa D'Amore
Pacôme Lecot
Kerstin Neininger
Margot Lorrain
Laetitia Gambotti
Caroline Dreuillet
Elise Courcault
Sampurna Chatterjee
Julio Delgado

Frontiers in Immunology

doi 10.3389/fimmu.2025.1567582

168 views

Original Research

Accepted on 24 Mar 2025

Prior Corticosteroid Treatment Alters cPBMC Composition and IFNɣ Response to Immunotherapy in Canine Cancer

in Cancer Immunity and Immunotherapy

Anna Barbara Emilia Zimmermann
Betül Taskoparan
Daniel Fuchs
Stanislav Pantelyushin
Mathischan Maheswaran
Manuela Schnyder
Sonja Hartnack
Rohrer Bley Carla
Johannes vom Berg

Frontiers in Immunology

doi 10.3389/fimmu.2025.1544949