Frontiers in Immunology | Cancer Immunity and Immunotherapy

Original Research

Published on 28 Mar 2025

Peripheral blood markers predict prognosis and irAEs of stage IV driver gene-negative lung adenocarcinoma treated with ICIs

in Cancer Immunity and Immunotherapy

Yu Li
Lei Cao
Lei Liu
Yawen Ding
Feng Cao

Frontiers in Immunology

doi 10.3389/fimmu.2025.1538392

734 views

Original Research

Published on 28 Mar 2025

Unveiling the power of Treg.Sig: a novel machine-learning derived signature for predicting ICI response in melanoma

in Cancer Immunity and Immunotherapy

Yunlong Fan
Jiaman Yang
Xin Yang
Yulin Xie
Haiyang Li
Shuo Yang
Guanchao Sun
Ge Ge
Xiao Ding
Shengwei Lai

Frontiers in Immunology

doi 10.3389/fimmu.2025.1508638

1,004 views

Original Research

Published on 28 Mar 2025

A prediction model based on machine learning: prognosis of HBV-induced HCC male patients with smoking and drinking habits after local ablation treatment

in Cancer Immunity and Immunotherapy

Han Shi
Caixia Hu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1464863

802 views

Original Research

Published on 28 Mar 2025

The outcomes and treatment strategies in metastatic soft tissue sarcoma treated with immunotherapy-based therapy: a three-center study

in Cancer Immunity and Immunotherapy

Zhiyong Liu
Yao Weitao
Kang Cui
Songtao Gao
Xin Wang
Peng Zhang
Jiaqiang Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1504117

688 views

Original Research

Published on 28 Mar 2025

Development of high-titer class-switched antibody responses to phosphorylated amino acids is prevalent in pancreatic ductal adenocarcinoma

in Cancer Immunity and Immunotherapy

Talita Aguiar
Shunya Mashiko
Kesava Asam
Poulomi Roy
Shikun Wang
Katharina Frank
Max Dietzel
Luca G. Z. Schahadat
Mattea Ausmeier
Andrea Hertel

Frontiers in Immunology

doi 10.3389/fimmu.2025.1501943

596 views

Mini Review

Published on 28 Mar 2025

γδT cells, a key subset of T cell for cancer immunotherapy

in Cancer Immunity and Immunotherapy

Jianzhen Lv
Zheng Liu
Xiangting Ren
Siyuan Song
Yan Zhang
Yi Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1562188

993 views

Original Research

Published on 28 Mar 2025

Transcriptomic signatures in peripheral CD4+T-lymphocytes may reflect melanoma staging and immunotherapy responsiveness prior to ICI initiation

in Cancer Immunity and Immunotherapy

Eleni Palli
Matthieu Lavigne
Panagiotis Verginis
Themis Alissafi
Amalia Anastasopoulou
Georgios Lyrarakis
John M. Kirkwood
Helen Gogas
Dimitrios C. Ziogas

Frontiers in Immunology

doi 10.3389/fimmu.2025.1529707

928 views

Case Report

Published on 28 Mar 2025

Case Report: Subacute cutaneous lupus erythematosus induced by the anti-PD-1 antibody camrelizumab combined with chemotherapy

in Cancer Immunity and Immunotherapy

Hejing Bao
Jiani Zhang
Xi Luo
Xiaojing Song
Juan Li
Nan Mao
Fang Chen
Hehong Bao
Jiazhu Hu
Xiaolong Cao

Frontiers in Immunology

doi 10.3389/fimmu.2025.1539373

714 views

General Commentary

Published on 27 Mar 2025

Commentary: The ubiquitin-proteasome system in the tumor immune microenvironment: a key force in combination therapy

in Cancer Immunity and Immunotherapy

Lu Zhang
Liping Jia
Linhan Wang
Wenxiu Yuan
Xin Shi

Frontiers in Immunology

doi 10.3389/fimmu.2025.1522427

455 views

Original Research

Published on 27 Mar 2025

Identification of a novel prognostic marker ADGRG6 in pancreatic adenocarcinoma: multi-omics analysis and experimental validation

in Cancer Immunity and Immunotherapy

Han Wu
Jin Shang
Yuanyan Bao
Huajie Liu
Haoran Zhang
Yaosheng Xiao
Yangtaobo Li
Zhaozhang Huang
Xiaolei Cheng
Zixuan Ma

Frontiers in Immunology

doi 10.3389/fimmu.2025.1530789

840 views

Original Research

Published on 27 Mar 2025

Comprehensive pan-cancer analysis indicates key gene of p53-independent apoptosis is a novel biomarker for clinical application and chemotherapy in colorectal cancer

in Cancer Immunity and Immunotherapy

Jianing Yan
Jingzhi Wang
Min Miao
Yongfu Shao

Frontiers in Immunology

doi 10.3389/fimmu.2025.1571137

925 views

Original Research

Published on 27 Mar 2025

Characterization of TLR9 responsiveness in cell subsets derived from in vitro pDC differentiation of hematopoietic stem and progenitor cells

in Cancer Immunity and Immunotherapy

Sabina Sánchez Hernández
Tobias Wang Bjerg
Ian Helstrup Nielsen
Anders Laustsen
Hai Q Tang
Lars Henning Pedersen
Eynav Klechevsky
Martin R. Jakobsen
Rasmus O. Bak

Frontiers in Immunology

doi 10.3389/fimmu.2025.1550397

1,047 views

Original Research

Published on 27 Mar 2025

Pan-cancer analysis reveals MTTP as a prognostic and immunotherapeutic biomarker in human tumors

in Cancer Immunity and Immunotherapy

Wenjia Wang
Yaping Gao
Yihan Liu
Shurui Xia
Jiayao Xu
Liwei Qin
Yongxu Jia
Yanru Qin

Frontiers in Immunology

doi 10.3389/fimmu.2025.1549965

1,105 views

Original Research

Published on 27 Mar 2025

Improved CAR internalization and recycling through transmembrane domain optimization reduces CAR-T cytokine release and exhaustion

in Cancer Immunity and Immunotherapy

Shufeng Xie
Jinlan Long
Ruiheng Wang
Rufang Xiang
Huajian Xian
Yixin Wang
Weiyu Dou
Wenjie Zhang
Dan Li
Ting Kang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1531344

1,111 views

Original Research

Published on 27 Mar 2025

Neoadjuvant immunotherapy for NSCLC: superior combination strategies, optimal treatment cycles, and predictive indicators from a Bayesian meta-analysis

in Cancer Immunity and Immunotherapy

Yubingxue Liu
Jianlin Long
Huan Deng
Wen Chen

Frontiers in Immunology

doi 10.3389/fimmu.2025.1548665

908 views

Original Research

Published on 27 Mar 2025

Melanocortin-1 receptor expression as a predictive factor for postoperative outcomes in melanoma patients: a retrospective study

in Cancer Immunity and Immunotherapy

Tian Xiang
Haiying Li
Xiaowei Wang
Danke Su

Frontiers in Immunology

doi 10.3389/fimmu.2025.1570502

489 views