Frontiers in Immunology | Cancer Immunity and Immunotherapy

Original Research

Published on 02 Apr 2025

Metabolomic machine learning-based model predicts efficacy of chemoimmunotherapy for advanced lung squamous cell carcinoma

in Cancer Immunity and Immunotherapy

Liang Zheng
Wei Nie
Shuyuan Wang
Ling Yang
Fang Hu
Meili Ma
Lei Cheng
Jun Lu
Bo Zhang
Jianlin Xu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1545976

851 views

Review

Published on 02 Apr 2025

Unraveling the triad of immunotherapy, tumor microenvironment, and skeletal muscle biomechanics in oncology

in Cancer Immunity and Immunotherapy

Shuang Ma
Ying Lu
Shang Sui
Jia-shuo Yang
Bing-bing Fu
Pei-xin Tan
Yicheng Chai
Jiaqi Lv
Lingyu Kong
Xiaolin Wu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1572821

587 views

Systematic Review

Published on 02 Apr 2025

The role of TACE in the era of immune-targeted therapy for hepatocellular carcinoma: a meta-analysis based on PSM

in Cancer Immunity and Immunotherapy

Jiahao Li
Lei Xian
Xinsen Wang
Yingnan Liu
Jiarui Li

Frontiers in Immunology

doi 10.3389/fimmu.2025.1573834

665 views

Review

Published on 02 Apr 2025

Where lung cancer and tuberculosis intersect: recent advances

in Cancer Immunity and Immunotherapy

Chunju Fang
Xuanlu He
Fei Tang
Zi Wang
Cong Pan
Qi Zhang
Jing Wu
Qinglan Wang
Daishun Liu
Yu Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1561719

615 views

Mini Review

Published on 02 Apr 2025

Immune microenvironment and immunotherapy in hepatocellular carcinoma: mechanisms and advances

in Cancer Immunity and Immunotherapy

Dong Xie
Yang Liu
Fangbiao Xu
Zhibo Dang
Mengge Li
Qinsheng Zhang
Zhongqin Dang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1581098

782 views

Review

Accepted on 01 Apr 2025

Nervous system-gut microbiota-immune system axis: Future directions for preventing tumor

in Cancer Immunity and Immunotherapy

Juan Juan Wang
Wenyue Cheng
Rongcun Yang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1535955

566 views

Review

Accepted on 01 Apr 2025

Identification of B cell antigens in solid cancer: Initial insights and functional implications

in Cancer Immunity and Immunotherapy

Min Yao
Jung-In Yang
Philip Moresco
Douglas Fearon

Frontiers in Immunology

doi 10.3389/fimmu.2025.1571570

Original Research

Accepted on 01 Apr 2025

An immune cell activation signature reflected hepatocellular carcinoma heterogeneity and predicted clinical outcomes

in Cancer Immunity and Immunotherapy

Xiaofeng Wang
Dongli Liu
Shuai Wang
Rui He

Frontiers in Immunology

doi 10.3389/fimmu.2025.1534611

Review

Accepted on 01 Apr 2025

The impact of the tumor microenvironment on macrophages

in Cancer Immunity and Immunotherapy

Xiaoduan Li
Man Xiao

Frontiers in Immunology

doi 10.3389/fimmu.2025.1572764

Original Research

Accepted on 01 Apr 2025

Multi-omics identification of a polyamine metabolism related signature for hepatocellular carcinoma and revealing tumor microenvironment characteristics

in Cancer Immunity and Immunotherapy

Yuexi Yu
Huiru Liu
Kaipeng Liu
Meiqi Zhao
Yiyan Zhang
Runci Jiang
Fengmei Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1570378

Original Research

Accepted on 01 Apr 2025

Trifunctional antibody-cytokine fusion protein formats for tumortargeted combination of IL-15 with IL-7 or IL-21

in Cancer Immunity and Immunotherapy

Annika M Möller
Sarah Vettermann
Felix Baumann
Max Pütter
Dafne Müller

Frontiers in Immunology

doi 10.3389/fimmu.2025.1498697

Review

Published on 01 Apr 2025

In the era of targeted therapy and immunotherapy: advances in the treatment of large B-cell lymphoma of immune-privileged sites

in Cancer Immunity and Immunotherapy

Haotian Wang
Ying Zhang
Xin Wan
Zhaoxia Li
Ou Bai

Frontiers in Immunology

doi 10.3389/fimmu.2025.1547377

498 views

Review

Published on 01 Apr 2025

Deciphering T-cell exhaustion in the tumor microenvironment: paving the way for innovative solid tumor therapies

in Cancer Immunity and Immunotherapy

Reshmi Nair
Veena Somasundaram
Anshu Kuriakose
Shiv Ram Krishn
David Raben
Rachel Salazar
Pradip Nair

Frontiers in Immunology

doi 10.3389/fimmu.2025.1548234

1,725 views

Original Research

Published on 01 Apr 2025

Moringa oleifera leaves protein suppresses T-lymphoblastic leukemogenesis via MAPK/AKT signaling modulation of apoptotic activation and autophagic flux regulation

in Cancer Immunity and Immunotherapy

Xiaoxue Liu
Hao Yang
Shanna Xie
Xinyu Wang
Yang Tian
Shuang Song

Frontiers in Immunology

doi 10.3389/fimmu.2025.1546189

653 views

Original Research

Published on 01 Apr 2025

Unveiling purine metabolism dysregulation orchestrated immunosuppression in advanced pancreatic cancer and concentrating on the central role of NT5E

in Cancer Immunity and Immunotherapy

Junqian Zhang
Xiaobo Zhang
Ruixin Wu
Chang-Sheng Dong

Frontiers in Immunology

doi 10.3389/fimmu.2025.1569088

624 views

Review

Published on 01 Apr 2025

The role of the tumor microenvironment in HNSCC resistance and targeted therapy

in Cancer Immunity and Immunotherapy

Zhaomeng Guo
Kang Li
Xiaotong Ren
Xijia Wang
Dunhui Yang
Shibo Ma
Xianhai Zeng
Peng Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1554835

709 views