Frontiers in Immunology | Cancer Immunity and Immunotherapy

Original Research

Accepted on 04 Apr 2025

Quantifying treatment response to a macrophage-targeted therapy in combination with immune checkpoint inhibitors after exposure to conventional chemotherapy

in Cancer Immunity and Immunotherapy

Shelby N Bess
Gaven K Smart
Timothy Muldoon

Frontiers in Immunology

doi 10.3389/fimmu.2025.1565953

Original Research

Accepted on 04 Apr 2025

A predictive model for the transformation from cervical inflammation to cancer based on tumor immune-related factors

in Cancer Immunity and Immunotherapy

Wenjie Wang
HUANG CHUN TAO
Shiwen Bi
Huiting Liang
Songlin Li
Tingting Lu
Ben Liu
Yong Tang
Wang Qi

Frontiers in Immunology

doi 10.3389/fimmu.2025.1532048

Original Research

Accepted on 04 Apr 2025

To Determine the Role of TRIT1 in the Diagnosis, Prognosis and Immunoinvasion of Liver Hepatocellular Carcinoma

in Cancer Immunity and Immunotherapy

Xinyu Niu
Xiaona Pan
Guifang He
Chao Xuan
Qingwu Tian
Yuan Yuan
Jingqiu Chen
Yaqi Song
Yujuan Tang
Tingting Zhou

Frontiers in Immunology

doi 10.3389/fimmu.2025.1563442

Case Report

Published on 04 Apr 2025

Case Report: Successful use of emapalumab in adult B-cell acute lymphoblastic leukemia experiencing severe neurotoxicity and hemophagocytic lymphohistiocytosis-like features after CAR-T cell therapy

in Cancer Immunity and Immunotherapy

Beatrice Manghisi
Giulia Cotilli
Marilena Fedele
Paola Perfetti
Elisabetta Terruzzi
Luisa Verga
Lorenza Maria Borin
Andrea Carrer
Monica Fumagalli
Maria Beatrice Ferrari

Frontiers in Immunology

doi 10.3389/fimmu.2025.1563736

662 views

Original Research

Published on 04 Apr 2025

Clinical potential and experimental validation of prognostic genes in hepatocellular carcinoma revealed by risk modeling utilizing single cell and transcriptome constructs

in Cancer Immunity and Immunotherapy

Hang Deng
Xu Wang
Zi-Ang Jiang
Jian Xu
Yu Zhang
Yao Zhou
Jun Gong
Xiang-Yu Lu
Yi-Fu Hou
Hao Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1541252

443 views

Review

Published on 04 Apr 2025

Single-cell and spatial transcriptomic insights into glioma cellular heterogeneity and metabolic adaptations

in Cancer Immunity and Immunotherapy

Yixin Fu
Yong Yi
Yongxiang Shao
Jingcheng Jiang
Qingshan Deng

Frontiers in Immunology

doi 10.3389/fimmu.2025.1561388

510 views

Review

Published on 04 Apr 2025

Senescence, NK cells, and cancer: navigating the crossroads of aging and disease

in Cancer Immunity and Immunotherapy

Marina Gergues
Rafijul Bari
Sharmila Koppisetti
Anna Gosiewska
Lin Kang
Robert J. Hariri

Frontiers in Immunology

doi 10.3389/fimmu.2025.1565278

1,147 views

Review

Published on 04 Apr 2025

A novel cancer-associated lncRNA, LINC01123, participates in tumor progression, metabolism, immune escape, and resistance

in Cancer Immunity and Immunotherapy

Qiang Liu
He Huang
Shuwen Zhang
Fangteng Liu
Ting Lou

Frontiers in Immunology

doi 10.3389/fimmu.2025.1480447

352 views

Original Research

Published on 04 Apr 2025

Development and validation of a disulfidptosis-related genes signature for predicting outcomes and immunotherapy in acute myeloid leukemia

in Cancer Immunity and Immunotherapy

Han Gong
Ying Zhang
Xusheng Wu
Yiming Pan
Mingwei Wang
Xiaofeng He
Jing Liu
Zhong Liu
Ling Li

Frontiers in Immunology

doi 10.3389/fimmu.2025.1513040

392 views

Original Research

Published on 04 Apr 2025

Identification and validation of HOXC6 as a diagnostic biomarker for Ewing sarcoma: insights from machine learning algorithms and in vitro experiments

in Cancer Immunity and Immunotherapy

Yonghua Pang
Jiahui Liang
Yakai Deng
Weinan Chen
Yunyan Shen
Jing Li
Xin Wang
Zhiyao Ren

Frontiers in Immunology

doi 10.3389/fimmu.2025.1449355

457 views

Original Research

Published on 04 Apr 2025

HLA-mismatched stem cell microtransplant prolonged overall survival and promoted immunological reconstitution for multiple myeloma

in Cancer Immunity and Immunotherapy

Yangyang Lei
Bo Cai
Zhiqing Liu
Anli Xie
Jianhui Qiao
Yi Wang
Xinrui Chen
Fei Peng
Yingxin Zhao
Jiaxin Chen

Frontiers in Immunology

doi 10.3389/fimmu.2025.1509588

389 views

Original Research

Accepted on 03 Apr 2025

Identification and Functional Characterization of Prognosis-Related Ferroptosis-Associated lncRNAs in Colorectal Cancer

in Cancer Immunity and Immunotherapy

Xiaoxu Ge
Jiasheng Xu
Jinjie He
Jian Wang
Yucheng Qian

Frontiers in Immunology

doi 10.3389/fimmu.2025.1561210

Case Report

Accepted on 03 Apr 2025

Pathological Complete Response after Monotherapy with Immune Checkpoint Inhibitors for Bifocal Colon Cancer in a Patient with Lynch syndrome And Situs Inversus Totalis: A Case Report

in Cancer Immunity and Immunotherapy

Jun Feng
Wenbo Niu
Juan Zhang
Yuanyi Ding
Zheng Li
Zhang Jianfeng
Baokun Li
Chenhui Li
Wang Feifei
Guiying Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1571607

Review

Accepted on 03 Apr 2025

From Neglect to Necessity: The Role of Innate Immunity in Cutaneous Squamous Cell Carcinoma Therapy

in Cancer Immunity and Immunotherapy

Yong He
Ting Tian
Yuancheng Li
Xiaoke Wang
Leqi Qian
Tian Tian
Mingjun Jiang
Liming Li

Frontiers in Immunology

doi 10.3389/fimmu.2025.1570032

Case Report

Accepted on 03 Apr 2025

Intrathecal administration of PD-1 inhibitor combined with pemetrexed for leptomeningeal metastases from breast cancer: a case report

in Cancer Immunity and Immunotherapy

Zhenyu Pan
Yushan Huang
Miaomiao Liu
Panpan Tai
Xiao Chen
Min Liu
Guozi Yang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1567324

Correction

Accepted on 03 Apr 2025

Corrigendum: Enhancing oncolytic virotherapy by extracellular vesicle mediated microRNA reprograming of the tumour microenvironment

in Cancer Immunity and Immunotherapy

Victoria A Jennings
Graham P Cook
Fiona Errington-Mais

Frontiers in Immunology

doi 10.3389/fimmu.2025.1601201