Frontiers in Immunology | Cancer Immunity and Immunotherapy

Original Research

Accepted on 17 Jan 2025

NOX4 Modulates Breast Cancer Progression Through Cancer Cell Metabolic Reprogramming and CD8 + T Cell Antitumor Activity

in Cancer Immunity and Immunotherapy

Yingying Xiong
Yiming Weng
Shan Zhu
Jian Qin
Jia Feng
Xiaopeng Jing
Chao Luo
Gong Wei
Rui Sun
Min Peng

Frontiers in Immunology

doi 10.3389/fimmu.2025.1534936

Original Research

Accepted on 17 Jan 2025

Diethyldithiocarbamate-copper complex ignites the tumor microenvironment through NKG2D-NKG2DL axis

in Cancer Immunity and Immunotherapy

Daciana Catalina Dumut
Marian Hajduch
Amanda M Zacharias
Qingling Duan
Ivo Frydrych
Zuzana Rozankova
Miroslav Popper
Dusan Garic
Radu Alexandru Paun
Amanda Centorame

Frontiers in Immunology

doi 10.3389/fimmu.2025.1491450

Review

Accepted on 17 Jan 2025

Cancer Stem Cells and Tumor-Associated Macrophages as Mates in Tumor Progression: mechanisms of crosstalk and advanced bioinformatic tools to dissect their phenotypes and interaction

in Cancer Immunity and Immunotherapy

Francesco Verona
Sebastiano Di Bella
Roberto Schirano
Camilla Manfredi
Francesca Angeloro
Giulia Bozzari
Matilde Todaro
Giuseppe Giannini
Giorgio Stassi
Veronica Veschi

Frontiers in Immunology

doi 10.3389/fimmu.2025.1529847

Editorial

Accepted on 17 Jan 2025

Community Series in Adenosine Pathways in Cancer Immunity and Immunotherapy: Volume II

in Cancer Immunity and Immunotherapy

Junjiang Fu
Luca Antonioli
Xiaoli Zheng
Ali Hafez El-Far

Frontiers in Immunology

doi 10.3389/fimmu.2025.1538930

Review

Accepted on 17 Jan 2025

Cell fusion as a driver of metastasis: re-evaluating an old hypothesis in the age of cancer heterogeneity

in Cancer Immunity and Immunotherapy

Eduardo López-Collazo
Laura Hurtado-Navarro

Frontiers in Immunology

doi 10.3389/fimmu.2025.1524781

Correction

Accepted on 17 Jan 2025

Corrigendum: Subtype-specific human endogenous retrovirus K102 envelope protein is a novel serum immunosuppressive biomarker of cancer

in Cancer Immunity and Immunotherapy

Qinyuan Gong
Rongzhen Xu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1560546

Mini Review

Accepted on 17 Jan 2025

Advancements in cellular immunotherapy: overcoming resistance in lung and colorectal cancer

in Cancer Immunity and Immunotherapy

Lijuan Qin
Yuan Li
Juan Liu
Xiaoqin An

Frontiers in Immunology

doi 10.3389/fimmu.2025.1554256

Original Research

Accepted on 17 Jan 2025

Single-Cell Sequencing Elucidates the Mechanism of NUSAP1 in Glioma and Its Diagnostic and Prognostic Significance

in Cancer Immunity and Immunotherapy

Mengyu Zhao
Zhao-Lei Shen
Hongzhen Dai
Wan-Yan Xu
Lina Wang
Tian-Hang Yu
Cun-Zhi Wang
JiaFeng Xu
Guan-Jun Chen
Dong-Hui Chen

Frontiers in Immunology

doi 10.3389/fimmu.2025.1512867

Original Research

Accepted on 17 Jan 2025

IFNβ drives ferroptosis through elevating TRIM22 and promotes the cytotoxicity of RSL3

in Cancer Immunity and Immunotherapy

Jun Lu
Huiyue Dong
Ling Zhu
Jingjing Sun
Qiuyan Chen
Pengyang Liu
Wei Zhang
Huajing Zeng
Rong Lin
Zongyang Yu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1535554

Review

Accepted on 17 Jan 2025

KLF4: A Multifunctional Nexus Connecting Tumor Progression and Immune Regulation

in Cancer Immunity and Immunotherapy

Yunjie Ju
Wen Xiao
Bryan James Mathis
Ying Shi

Frontiers in Immunology

doi 10.3389/fimmu.2025.1514780

Original Research

Accepted on 17 Jan 2025

HPK1 Kinase Inhibitor: A Sufficient Approach to Target HPK1 to Modulate T Cell Activation in Cancer Immunotherapy Compared with Degraders

in Cancer Immunity and Immunotherapy

Qin Wang
Xinyi Zhu
Jing Li
Sanjia Xu
Ali Wang
Xinwen Zhang
Xingxing Wang
Xiaopeng Cai
Haimei Xing
Ye Liu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1449106

Systematic Review

Published on 17 Jan 2025

The prognostic value of circulating tumor DNA in malignant melanoma patients treated with immune checkpoint inhibitors: a systematic review and meta-analysis

in Cancer Immunity and Immunotherapy

Lei Liu
Shufu Hou
Aiping Zhu
Bing Yan
Linchuan Li
Dandan Song

Frontiers in Immunology

doi 10.3389/fimmu.2024.1520441

153 views

Original Research

Published on 17 Jan 2025

Characterizing tumor biology and immune microenvironment in high-grade serous ovarian cancer via single-cell RNA sequencing: insights for targeted and personalized immunotherapy strategies

in Cancer Immunity and Immunotherapy

Fu Zhao
Xiaojing Jiang
Yumeng Li
Tianjiao Huang
Zhikai Xiahou
Wenyang Nie
Qian Li

Frontiers in Immunology

doi 10.3389/fimmu.2024.1500153

120 views

Original Research

Published on 17 Jan 2025

Efficacy and safety of neoadjuvant chemoimmunotherapy and chemotherapy in patients with potentially resectable stage IIIA/IIIB NSCLC: a retrospective study

in Cancer Immunity and Immunotherapy

Yuchen Wang
Xiaobo Ma
Kewei Ma
Xi Chen
Hua He
Xiangye Zhao
Mengge Fan
Yinghui Xu

Frontiers in Immunology

doi 10.3389/fimmu.2024.1479263

Original Research

Published on 17 Jan 2025

High-dose ascorbic acid synergizes with anti-PD1 therapy in non-small cell lung cancer in vitro and in vivo models

in Cancer Immunity and Immunotherapy

Hak Su Kim
Seung-hyun Kwon
Ok Kyung Choi
Taekyu Lim

Frontiers in Immunology

doi 10.3389/fimmu.2024.1512605

293 views

Mini Review

Published on 17 Jan 2025

New insights into the mechanisms of the immune microenvironment and immunotherapy in osteosarcoma

in Cancer Immunity and Immunotherapy

Cong Luo
Xingxing Min
Danying Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2024.1539696

105 views

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Articles

NOX4 Modulates Breast Cancer Progression Through Cancer Cell Metabolic Reprogramming and CD8 + T Cell Antitumor Activity

Diethyldithiocarbamate-copper complex ignites the tumor microenvironment through NKG2D-NKG2DL axis

Cancer Stem Cells and Tumor-Associated Macrophages as Mates in Tumor Progression: mechanisms of crosstalk and advanced bioinformatic tools to dissect their phenotypes and interaction

Community Series in Adenosine Pathways in Cancer Immunity and Immunotherapy: Volume II

Cell fusion as a driver of metastasis: re-evaluating an old hypothesis in the age of cancer heterogeneity

Corrigendum: Subtype-specific human endogenous retrovirus K102 envelope protein is a novel serum immunosuppressive biomarker of cancer

Advancements in cellular immunotherapy: overcoming resistance in lung and colorectal cancer

Single-Cell Sequencing Elucidates the Mechanism of NUSAP1 in Glioma and Its Diagnostic and Prognostic Significance

IFNβ drives ferroptosis through elevating TRIM22 and promotes the cytotoxicity of RSL3

KLF4: A Multifunctional Nexus Connecting Tumor Progression and Immune Regulation

HPK1 Kinase Inhibitor: A Sufficient Approach to Target HPK1 to Modulate T Cell Activation in Cancer Immunotherapy Compared with Degraders

The prognostic value of circulating tumor DNA in malignant melanoma patients treated with immune checkpoint inhibitors: a systematic review and meta-analysis

Characterizing tumor biology and immune microenvironment in high-grade serous ovarian cancer via single-cell RNA sequencing: insights for targeted and personalized immunotherapy strategies

Efficacy and safety of neoadjuvant chemoimmunotherapy and chemotherapy in patients with potentially resectable stage IIIA/IIIB NSCLC: a retrospective study

High-dose ascorbic acid synergizes with anti-PD1 therapy in non-small cell lung cancer in vitro and in vivo models

New insights into the mechanisms of the immune microenvironment and immunotherapy in osteosarcoma