Frontiers in Genetics | Toxicogenomics

Original Research

Published on 03 Dec 2018

Persistence of Epigenomic Effects After Recovery From Repeated Treatment With Two Nephrocarcinogens

in Toxicogenomics

Alice Limonciel
Simone G. van Breda
Xiaoqi Jiang
Gregory D. Tredwell
Anja Wilmes
Lydia Aschauer
Alexandros P. Siskos
Agapios Sachinidis
Hector C. Keun
Annette Kopp-Schneider

Frontiers in Genetics

doi 10.3389/fgene.2018.00558

4,898 views
5 citations

Original Research

Published on 28 Nov 2018

Beta 1, Beta 2 and Beta 3 Adrenergic Receptor Gene Polymorphisms in a Southeastern European Population

in Toxicogenomics

Martha-Spyridoula Katsarou
Aikaterini Karathanasopoulou
Angeliki Andrianopoulou
Vasileios Desiniotis
Efthymios Tzinis
Efthimios Dimitrakis
Maria Lagiou
Evangelia Charmandari
Michael Aschner
Aristeidis M. Tsatsakis

Frontiers in Genetics

doi 10.3389/fgene.2018.00560

43,351 views
24 citations

Original Research

Published on 27 Nov 2018

Prediction of Drug-Likeness Using Deep Autoencoder Neural Networks

in Toxicogenomics

Qiwan Hu
Mudong Feng
Luhua Lai
Jianfeng Pei

Frontiers in Genetics

doi 10.3389/fgene.2018.00585

13,335 views
60 citations

Editorial

Published on 27 Nov 2018

Editorial: Integrative Toxicogenomics: Analytical Strategies to Amalgamate Exposure Effects With Genomic Sciences

in Toxicogenomics

Pierre R. Bushel
Weida Tong

Frontiers in Genetics

doi 10.3389/fgene.2018.00563

1,677 views
2 citations

Original Research

Published on 20 Nov 2018

Embracing the Dark Side: Computational Approaches to Unveil the Functionality of Genes Lacking Biological Annotation in Drug-Induced Liver Injury

in Toxicogenomics

Terezinha Souza
Panuwat Trairatphisan
Janet Piñero
Laura I. Furlong
Julio Saez-Rodriguez
Jos Kleinjans
Danyel Jennen

Frontiers in Genetics

doi 10.3389/fgene.2018.00527

4,486 views

Original Research

Published on 01 Nov 2018

Robust Co-clustering to Discover Toxicogenomic Biomarkers and Their Regulatory Doses of Chemical Compounds Using Logistic Probabilistic Hidden Variable Model

in Toxicogenomics

Mohammad Nazmol Hasan
Md. Masud Rana
Anjuman Ara Begum
Moizur Rahman
Md. Nurul Haque Mollah

Frontiers in Genetics

doi 10.3389/fgene.2018.00516

2,477 views
10 citations

Original Research

Published on 30 Oct 2018

A Comparison of the TempO-Seq S1500+ Platform to RNA-Seq and Microarray Using Rat Liver Mode of Action Samples

in Toxicogenomics

Pierre R. Bushel
Richard S. Paules
Scott S. Auerbach

Frontiers in Genetics

doi 10.3389/fgene.2018.00485

11,542 views
53 citations

Original Research

Published on 23 Oct 2018

AP-1 (bZIP) Transcription Factors as Potential Regulators of Metallothionein Gene Expression in Tetrahymena thermophila

in Toxicogenomics

Patricia de Francisco
Francisco Amaro
Ana Martín-González
Juan Carlos Gutiérrez

Frontiers in Genetics

doi 10.3389/fgene.2018.00459

5,282 views
9 citations

Original Research

Published on 22 Oct 2018

Network and Pathway Analysis of Toxicogenomics Data

in Toxicogenomics

Gal Barel
Ralf Herwig

Frontiers in Genetics

doi 10.3389/fgene.2018.00484

8,838 views
26 citations

Original Research

Published on 02 Oct 2018

Investigation of Nrf2, AhR and ATF4 Activation in Toxicogenomic Databases

in Toxicogenomics

Elias Zgheib
Alice Limonciel
Xiaoqi Jiang
Anja Wilmes
Steven Wink
Bob van de Water
Annette Kopp-Schneider
Frederic Y. Bois
Paul Jennings

Frontiers in Genetics

doi 10.3389/fgene.2018.00429

9,642 views
24 citations

Original Research

Published on 18 Sep 2018

Analysis of Time-Series Gene Expression Data to Explore Mechanisms of Chemical-Induced Hepatic Steatosis Toxicity

in Toxicogenomics

Alejandro Aguayo-Orozco
Frederic Yves Bois
Søren Brunak
Olivier Taboureau

Frontiers in Genetics

doi 10.3389/fgene.2018.00396

16,503 views
23 citations

Review

Published on 12 Sep 2018

Molecular Pathways Associated With Methylmercury-Induced Nrf2 Modulation

in Toxicogenomics

Takamitsu Unoki
Masahiro Akiyama
Yoshito Kumagai
Filipe Marques Gonçalves
Marcelo Farina
João Batista Teixeira da Rocha
Michael Aschner

Frontiers in Genetics

doi 10.3389/fgene.2018.00373

9,399 views
57 citations

Original Research

Published on 31 Jul 2018

Zearalenone Exposure Enhanced the Expression of Tumorigenesis Genes in Donkey Granulosa Cells via the PTEN/PI3K/AKT Signaling Pathway

in Toxicogenomics

Guo-Liang Zhang
Jun-Lin Song
Chuan-Liang Ji
Yu-Long Feng
Jie Yu
Charles M. Nyachoti
Gong-She Yang

Frontiers in Genetics

doi 10.3389/fgene.2018.00293

3,779 views
19 citations

Original Research

Published on 27 Jul 2018

Genetic Susceptibility to Neurodegeneration in Amazon: Apolipoprotein E Genotyping in Vulnerable Populations Exposed to Mercury

in Toxicogenomics

Gabriela P. F. Arrifano
Rosa C. R. Martín-Doimeadios
María Jiménez-Moreno
Sergio Fernández-Trujillo
Marcus Augusto-Oliveira
José R. Souza-Monteiro
Barbarella M. Macchi
Jacqueline I. Alvarez-Leite
José L. M. do Nascimento
Marcos T. Amador

Frontiers in Genetics

doi 10.3389/fgene.2018.00285

5,551 views
40 citations

Editorial

Published on 19 Jun 2018

Editorial: Metal Biology Takes Flight: The Study of Metal Homeostasis and Detoxification in Insects

in Toxicogenomics

Stephanie E. Mohr
David W. Killilea

Frontiers in Genetics

doi 10.3389/fgene.2018.00221

2,316 views
4 citations

Original Research

Published on 15 Jun 2018

Sex-Dependent Effects of the Histone Deacetylase Inhibitor, Sodium Valproate, on Reversal Learning After Developmental Arsenic Exposure

in Toxicogenomics

Christina R. Steadman Tyler
Jane J. W. Smoake
Elizabeth R. Solomon
Estrella Villicana
Kevin K. Caldwell
Andrea M. Allan

Frontiers in Genetics

doi 10.3389/fgene.2018.00200

4,897 views
21 citations