Perspective

Published on 26 Nov 2012

Toward a clinical practice guide in pharmacogenomics testing for functional polymorphisms of drug-metabolizing enzymes. Gene/drug pairs and barriers perceived in Spain

in Pharmacogenetics and Pharmacogenomics

José A G Agúndez
Francisco Abad-Santos
Ana Aldea
Hortensia Alonso
María Luisa Bernal
Alberto Borobia
Emma Borras
Miguel Carballo
Alfonso Carvajal
José D García-Muñiz

Frontiers in Genetics

doi 10.3389/fgene.2012.00273

8,381 views
24 citations

Review

Published on 22 Nov 2012

Impact of genetic polymorphisms on chemotherapy toxicity in childhood acute lymphoblastic leukemia

in Pharmacogenetics and Pharmacogenomics

Guillermo Gervasini
Jose Manuel Vagace

Frontiers in Genetics

doi 10.3389/fgene.2012.00249

15,647 views
35 citations

Original Research

Published on 21 Nov 2012

Impact of the Interaction between 3′-UTR SNPs and microRNA on the Expression of Human Xenobiotic Metabolism Enzyme and Transporter Genes

in Pharmacogenetics and Pharmacogenomics

Rongrong Wei
Fan Yang
Thomas J. Urban
Lang Li
Naga Chalasani
David A Flockhart
Wanqing Liu

Frontiers in Genetics

doi 10.3389/fgene.2012.00248

8,232 views
33 citations

Opinion

Published on 16 Nov 2012

Genetic variations in drug-induced liver injury (DILI): resolving the puzzle

in Pharmacogenetics and Pharmacogenomics

Camilla Stephens
M Isabel Lucena
Raúl J Andrade

Frontiers in Genetics

doi 10.3389/fgene.2012.00253

4,647 views
12 citations

Review

Published on 12 Nov 2012

MDMA, methamphetamine, and CYP2D6 pharmacogenetics: what is clinically relevant?

in Pharmacogenetics and Pharmacogenomics

Rafael De La Torre
Samanta Yubero-Lahoz
Ricardo Pardo-Lozano
Magi Farre

Frontiers in Genetics

doi 10.3389/fgene.2012.00235

66,521 views
82 citations

Original Research

Published on 05 Nov 2012

ABCB1 4036A>G and 1236C>T Polymorphisms Affect Plasma Efavirenz Levels in South African HIV/AIDS Patients

in Pharmacogenetics and Pharmacogenomics

Marelize Swart
Yuan Ren
Peter Smith
Collet Dandara

Frontiers in Genetics

doi 10.3389/fgene.2012.00236

6,287 views
48 citations

Original Research

Published on 02 Nov 2012

Frequencies of 23 Functionally Significant Variant Alleles Related with Metabolism of Antineoplastic Drugs in the Chilean Population: Comparison with Caucasian and Asian Populations

in Pharmacogenetics and Pharmacogenomics

Angela Margarita Roco
Luis Abel Quiñones
José A G Agúndez
Elena García-Martín
Valentina Squicciarini
Carla Estefania Miranda
Joselyn Garay
Nancy Farfán
Iván Nicolás Saavedra
Dante Daniel Caceres

Frontiers in Genetics

doi 10.3389/fgene.2012.00229

10,037 views
66 citations

Review

Published on 10 Oct 2012

Molecular mechanisms of genetic variation and transcriptional regulation of CYP2C19

in Pharmacogenetics and Pharmacogenomics

Nuala Ann Helsby
Kathryn Elisa Burns

Frontiers in Genetics

doi 10.3389/fgene.2012.00206

9,038 views
28 citations

Review

Published on 06 Sep 2012

Translesion DNA Polymerases and Cancer

in Pharmacogenetics and Pharmacogenomics

Nick Makridakis
Juergen Reichardt

Frontiers in Genetics

doi 10.3389/fgene.2012.00174

23,099 views
55 citations

Mini Review

Published on 14 Aug 2012

Liver expression quantitative trait loci: a foundation for pharmacogenomic research

in Pharmacogenetics and Pharmacogenomics

Dylan Glubb
Neepa Dholakia
Federico Innocenti

Frontiers in Genetics

doi 10.3389/fgene.2012.00153

7,184 views
14 citations

Original Research

Published on 08 Aug 2012

Submitted for Your Consideration: Potential Advantages of a Novel Clinical Trial Design and Initial Patient Reaction

in Pharmacogenetics and Pharmacogenomics

Matthew Shane Loop
Alexis C. Frazier-Wood
Amy S. Thomas
Emily J. Dhurandhar
James M. Shikany
Gary L. Gadbury
David B Allison

Frontiers in Genetics

doi 10.3389/fgene.2012.00145

4,826 views
5 citations

Original Research

Published on 01 Sep 2011

Association of Allelic Variation in Genes Mediating Aspects of Energy Homeostasis with Weight Gain during Administration of Antipsychotic Drugs (CATIE Study)

in Pharmacogenetics and Pharmacogenomics

Hemant K Tiwari
Amit Patki
Jeffrey Lieberman
T. Scott Stroup
David B Allison
Rudolph L Leibel
Wendy K Chung

Frontiers in Genetics

doi 10.3389/fgene.2011.00056

6,560 views
19 citations

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Articles

Toward a clinical practice guide in pharmacogenomics testing for functional polymorphisms of drug-metabolizing enzymes. Gene/drug pairs and barriers perceived in Spain

Impact of genetic polymorphisms on chemotherapy toxicity in childhood acute lymphoblastic leukemia

Impact of the Interaction between 3′-UTR SNPs and microRNA on the Expression of Human Xenobiotic Metabolism Enzyme and Transporter Genes

Genetic variations in drug-induced liver injury (DILI): resolving the puzzle

MDMA, methamphetamine, and CYP2D6 pharmacogenetics: what is clinically relevant?

ABCB1 4036A>G and 1236C>T Polymorphisms Affect Plasma Efavirenz Levels in South African HIV/AIDS Patients

Frequencies of 23 Functionally Significant Variant Alleles Related with Metabolism of Antineoplastic Drugs in the Chilean Population: Comparison with Caucasian and Asian Populations

Molecular mechanisms of genetic variation and transcriptional regulation of CYP2C19

Translesion DNA Polymerases and Cancer

Liver expression quantitative trait loci: a foundation for pharmacogenomic research

Submitted for Your Consideration: Potential Advantages of a Novel Clinical Trial Design and Initial Patient Reaction

Association of Allelic Variation in Genes Mediating Aspects of Energy Homeostasis with Weight Gain during Administration of Antipsychotic Drugs (CATIE Study)