Original Research

Published on 05 Apr 2022

The Association Between Cyclooxygenase-2 –1195G/A (rs689466) Gene Polymorphism and the Clinicopathology of Lung Cancer in the Japanese Population: A Case-Controlled Study

in Human and Medical Genomics

Rong Sun
Ryosuke Tanino
Xuexia Tong
Minoru Isomura
Li-Jun Chen
Takamasa Hotta
Tamio Okimoto
Megumi Hamaguchi
Shunichi Hamaguchi
Yasuyuki Taooka

Frontiers in Genetics

doi 10.3389/fgene.2022.796444

2,292 views
1 citation

Perspective

Published on 05 Apr 2022

Microbiomics: The Next Pillar of Precision Medicine and Its Role in African Healthcare

in Human and Medical Genomics

C. K. Nkera-Gutabara
R. Kerr
J. Scholefield
S. Hazelhurst
J. Naidoo

Frontiers in Genetics

doi 10.3389/fgene.2022.869610

4,679 views
5 citations

Methods

Published on 04 Apr 2022

The Economic, Medical and Psychosocial Consequences of Whole Genome Sequencing for the Genetic Diagnosis of Patients With Intellectual Disability: The DEFIDIAG Study Protocol

in Human and Medical Genomics

Catherine Lejeune
Charley Robert-Viard
Nicolas Meunier-Beillard
Myriam Alice Borel
Léna Gourvès
Stéphanie Staraci
Anne-Laure Soilly
Francis Guillemin
Valerie Seror
Hamza Achit

Frontiers in Genetics

doi 10.3389/fgene.2022.852472

3,371 views
2 citations

Original Research

Published on 04 Apr 2022

The Prognostic Significance of RIMKLB and Related Immune Infiltrates in Colorectal Cancers

in Human and Medical Genomics

Yinghao Cao
Shenghe Deng
Lizhao Yan
Junnan Gu
Fuwei Mao
Yifan Xue
Le Qin
Zhengxing Jiang
Wentai Cai
Changmin Zheng

Frontiers in Genetics

doi 10.3389/fgene.2022.818994

4,006 views
4 citations

Original Research

Published on 01 Apr 2022

The Role of Copy Number Variants in Gene Co-Expression Patterns for Luminal B Breast Tumors

in Human and Medical Genomics

Candelario Hernández-Gómez
Enrique Hernández-Lemus
Jesús Espinal-Enríquez

Frontiers in Genetics

doi 10.3389/fgene.2022.806607

2,519 views
8 citations

Mini Review

Published on 31 Mar 2022

Therapeutic Targeting Hypoxia-Inducible Factor (HIF-1) in Cancer: Cutting Gordian Knot of Cancer Cell Metabolism

in Human and Medical Genomics

Abhilasha Sharma
Sonam Sinha
Neeta Shrivastava

Frontiers in Genetics

doi 10.3389/fgene.2022.849040

12,029 views
55 citations

Original Research

Published on 31 Mar 2022

Identification of a Novel Deep Intronic Variant by Whole Genome Sequencing Combined With RNA Sequencing in a Chinese Patient With Menkes Disease

in Human and Medical Genomics

Xiufang Zhi
Qi Ai
Wenchao Sheng
Yuping Yu
Jianbo Shu
Changshun Yu
Xiaoli Yu
Dong Li
Chunquan Cai

Frontiers in Genetics

doi 10.3389/fgene.2022.852764

3,476 views

Editorial

Published on 31 Mar 2022

Editorial: Clinical Genome Sequencing: Bioinformatics Challenges and Key Considerations

in Human and Medical Genomics

Shulan Tian
Zheng Jin Tu
Huihuang Yan
Eric W. Klee

Frontiers in Genetics

doi 10.3389/fgene.2022.896032

1,268 views

Original Research

Published on 31 Mar 2022

Comparison of Data Normalization Strategies for Array-Based MicroRNA Profiling Experiments and Identification and Validation of Circulating MicroRNAs as Endogenous Controls in Hypertension

in Human and Medical Genomics

Lakshmi Manasa S. Chekka
Taimour Langaee
Julie A. Johnson

Frontiers in Genetics

doi 10.3389/fgene.2022.836636

3,293 views
7 citations

Review

Published on 30 Mar 2022

Leveraging Optimized Transcriptomic and Personalized Stem Cell Technologies to Better Understand Syncytialization Defects in Preeclampsia

in Human and Medical Genomics

Sehee Choi
Teka Khan
R. Michael Roberts
Danny J. Schust

Frontiers in Genetics

doi 10.3389/fgene.2022.872818

3,287 views
2 citations

Mini Review

Published on 30 Mar 2022

Small Non-Coding RNAs in the Human Placenta: Regulatory Roles and Clinical Utility

in Human and Medical Genomics

Nikita Telkar
Greg L. Stewart
Michelle E. Pewarchuk
David E. Cohn
Wendy P. Robinson
Wan L. Lam

Frontiers in Genetics

doi 10.3389/fgene.2022.868598

2,803 views
7 citations

Case Report

Published on 29 Mar 2022

Case Report: Exome and RNA Sequencing Identify a Novel de novo Missense Variant in HNRNPK in a Chinese Patient With Au-Kline Syndrome

in Human and Medical Genomics

Xin Pan
Sihan Liu
Li Liu
Xu Zhang
Hong Yao
Bo Tan

Frontiers in Genetics

doi 10.3389/fgene.2022.853028

2,585 views
2 citations

Review

Published on 29 Mar 2022

Phospholipid Scramblases: Role in Cancer Progression and Anticancer Therapeutics

in Human and Medical Genomics

Himadri Gourav Behuria
Sabyasachi Dash
Santosh Kumar Sahu

Frontiers in Genetics

doi 10.3389/fgene.2022.875894

8,027 views
8 citations

Original Research

Published on 28 Mar 2022

Clinical and Genetic Characteristics of IKZF1 Mutation in Chinese Children With B-Cell Acute Lymphoblastic Leukemia

in Human and Medical Genomics

Jingying Zhang
Xiao-Jun Xu
Lixia Liu
Hua Song
Heping Shen
Weiqun Xu
Fenying Zhao
Juan Liang
Chan Liao
Yan Wang

Frontiers in Genetics

doi 10.3389/fgene.2022.822832

3,987 views
3 citations

Opinion

Published on 25 Mar 2022

Esophageal Cancer Genomics in Africa: Recommendations for Future Research

in Human and Medical Genomics

Hannah Simba
Gerard Tromp
Vikash Sewram
Christopher G Mathew
Wenlong C. Chen
Helena Kuivaniemi

Frontiers in Genetics

doi 10.3389/fgene.2022.864575

2,802 views
4 citations

Original Research

Published on 25 Mar 2022

Integration of Transcriptomic and Metabolomic Data to Compare the Hepatotoxicity of Neonatal and Adult Mice Exposed to Aristolochic Acid I

in Human and Medical Genomics

Zhi-e Fang
Chunyu Wang
Ming Niu
Tingting Liu
Lutong Ren
Qiang Li
Zhiyong Li
Ziying Wei
Li Lin
Wenqing Mu

Frontiers in Genetics

doi 10.3389/fgene.2022.840961

3,102 views
7 citations

Navigation group

Articles

The Association Between Cyclooxygenase-2 –1195G/A (rs689466) Gene Polymorphism and the Clinicopathology of Lung Cancer in the Japanese Population: A Case-Controlled Study

Microbiomics: The Next Pillar of Precision Medicine and Its Role in African Healthcare

The Economic, Medical and Psychosocial Consequences of Whole Genome Sequencing for the Genetic Diagnosis of Patients With Intellectual Disability: The DEFIDIAG Study Protocol

The Prognostic Significance of RIMKLB and Related Immune Infiltrates in Colorectal Cancers

The Role of Copy Number Variants in Gene Co-Expression Patterns for Luminal B Breast Tumors

Therapeutic Targeting Hypoxia-Inducible Factor (HIF-1) in Cancer: Cutting Gordian Knot of Cancer Cell Metabolism

Identification of a Novel Deep Intronic Variant by Whole Genome Sequencing Combined With RNA Sequencing in a Chinese Patient With Menkes Disease

Editorial: Clinical Genome Sequencing: Bioinformatics Challenges and Key Considerations

Comparison of Data Normalization Strategies for Array-Based MicroRNA Profiling Experiments and Identification and Validation of Circulating MicroRNAs as Endogenous Controls in Hypertension

Leveraging Optimized Transcriptomic and Personalized Stem Cell Technologies to Better Understand Syncytialization Defects in Preeclampsia

Small Non-Coding RNAs in the Human Placenta: Regulatory Roles and Clinical Utility

Case Report: Exome and RNA Sequencing Identify a Novel de novo Missense Variant in HNRNPK in a Chinese Patient With Au-Kline Syndrome

Phospholipid Scramblases: Role in Cancer Progression and Anticancer Therapeutics

Clinical and Genetic Characteristics of IKZF1 Mutation in Chinese Children With B-Cell Acute Lymphoblastic Leukemia

Esophageal Cancer Genomics in Africa: Recommendations for Future Research

Integration of Transcriptomic and Metabolomic Data to Compare the Hepatotoxicity of Neonatal and Adult Mice Exposed to Aristolochic Acid I