Frontiers in Genetics | Human and Medical Genomics

Original Research

Published on 30 Nov 2022

Targeted screening of genetic associations with COVID-19 susceptibility and severity

in Human and Medical Genomics

Ping Li
Yuehua Ke
Wenlong Shen
Shu Shi
Yahao Wang
Kailin Lin
Xinjie Guo
Changjun Wang
Yan Zhang
Zhihu Zhao

Frontiers in Genetics

doi 10.3389/fgene.2022.1073880

3,963 views
9 citations

Original Research

Published on 29 Nov 2022

The role of angiotensin I converting enzyme insertion/deletion polymorphism in the severity and outcomes of COVID-19 patients

in Human and Medical Genomics

Mitra Rezaei
Hadiseh Mohammadpour
Mahya Eftekhari
Mihan Pourabdollah
Farinaz Nasr Azadani
Payam Tabarsi
Majid Marjani
Seyed Ali Ziai

Frontiers in Genetics

doi 10.3389/fgene.2022.1035796

1,858 views
2 citations

Original Research

Published on 28 Nov 2022

Identification and characterization of novel elastin gene mutations in eleven families with supravalvular aortic stenosis

in Human and Medical Genomics

Jianrong Zhou
Yueheng Wu
Xiaoli Xu
Yong Zhang
Xiong Zhang
Haisheng Chen
Jian Zhuang
Jimei Chen
Yun Teng

Frontiers in Genetics

doi 10.3389/fgene.2022.1059640

3,217 views
6 citations

Case Report

Published on 25 Nov 2022

Case report: Identification of a frameshift mutation in GC enrichment and the GCC repeat region of the androgen insensitivity receptor (AR) gene in a patient with complete androgen insensitivity syndrome by whole-exome sequencing (WES) combined with specific PCR and deep sequencing

in Human and Medical Genomics

Xiaojing He
Qingya Ma
Qiaoli Zhang
Xutao Hong
Ming Qi
Yongkai Li
Xiaodong Li

Frontiers in Genetics

doi 10.3389/fgene.2022.1038997

2,827 views
2 citations

Original Research

Published on 24 Nov 2022

Epigenomic signatures associated with spontaneous and replication stress-induced DNA double strand breaks

in Human and Medical Genomics

Sravan Kodali
Silvia Meyer-Nava
Stephen Landry
Arijita Chakraborty
Juan Carlos Rivera-Mulia
Wenyi Feng

Frontiers in Genetics

doi 10.3389/fgene.2022.907547

3,477 views
2 citations

Review

Published on 24 Nov 2022

Genes in pediatric pulmonary arterial hypertension and the most promising BMPR2 gene therapy

in Human and Medical Genomics

Lingling Dai
Lizhong Du

Frontiers in Genetics

doi 10.3389/fgene.2022.961848

5,038 views
5 citations

Original Research

Published on 24 Nov 2022

Analyzing the Korean reference genome with meta-imputation increased the imputation accuracy and spectrum of rare variants in the Korean population

in Human and Medical Genomics

Mi Yeong Hwang
Nak-Hyeon Choi
Hong Hee Won
Bong-Jo Kim
Young Jin Kim

Frontiers in Genetics

doi 10.3389/fgene.2022.1008646

4,074 views
11 citations

Original Research

Published on 22 Nov 2022

Causal effects of homocysteine levels on the components of sarcopenia: A two-sample mendelian randomization study

in Human and Medical Genomics

Hongwei Yu
Gan Luo
Tianwei Sun
Qiong Tang

Frontiers in Genetics

doi 10.3389/fgene.2022.1051047

4,838 views
4 citations

Original Research

Published on 22 Nov 2022

Identifying key m6A-methylated lncRNAs and genes associated with neural tube defects via integrative MeRIP and RNA sequencing analyses

in Human and Medical Genomics

Jing Yang
Jing Xu
Luting Zhang
Yingting Li
Min Chen

Frontiers in Genetics

doi 10.3389/fgene.2022.974357

2,870 views
5 citations

Original Research

Published on 22 Nov 2022

Identification of subtypes of hepatocellular carcinoma and screening of prognostic molecular diagnostic markers based on cell adhesion molecule related genes

in Human and Medical Genomics

Ruge Sun
Yanchao Gao
Fengjun Shen

Frontiers in Genetics

doi 10.3389/fgene.2022.1042540

3,030 views
3 citations

Editorial

Published on 18 Nov 2022

Editorial: Cancer systems biology

in Human and Medical Genomics

Jesús Espinal-Enríquez
Claudia Rangel-Escareño
Frank Emmert-Streib

Frontiers in Genetics

doi 10.3389/fgene.2022.1083902

2,387 views

Original Research

Published on 18 Nov 2022

Abnormal expression of TSG-6 disturbs extracellular matrix homeostasis in chondrocytes from endemic osteoarthritis

in Human and Medical Genomics

Yujie Ning
Pan Zhang
Feiyu Zhang
Sijie Chen
Yanli Liu
Feihong Chen
Yifan Wu
Shujin Li
Chaowei Wang
Yi Gong

Frontiers in Genetics

doi 10.3389/fgene.2022.1064565

3,192 views
8 citations

Case Report

Published on 18 Nov 2022

Case report and a brief review: Analysis and challenges of prenatal imaging phenotypes and genotypes in Joubert syndrome

in Human and Medical Genomics

Ling-Xi Huang
Xian-Gui Lu
Jiao-Xiang Liu
Ling Xu
Ning Shang
Li Guo
Yan-Chun OuYang

Frontiers in Genetics

doi 10.3389/fgene.2022.1038274

2,879 views
8 citations

Original Research

Published on 17 Nov 2022

Integration of small RNAs from plasma and cerebrospinal fluid for classification of multiple sclerosis

in Human and Medical Genomics

Maria Needhamsen
Payam Emami Khoonsari
Galina Yurevna Zheleznyakova
Eliane Piket
Michael Hagemann-Jensen
Yanan Han
Jannik Gierlich
Diana Ekman
Maja Jagodic

Frontiers in Genetics

doi 10.3389/fgene.2022.1042483

2,492 views

Original Research

Published on 17 Nov 2022

Identification of four novel variants in the CDH23 gene from four affected families with hearing loss

in Human and Medical Genomics

Baoling Kang
Xinshu Lu
Jianjun Xiong
Yuan Li
Jinwen Zhu
Tao Cai

Frontiers in Genetics

doi 10.3389/fgene.2022.1027396

2,172 views
4 citations

Brief Research Report

Published on 14 Nov 2022

Establishment of transgenic pigs overexpressing human PKD2-D511V mutant

in Human and Medical Genomics

Yuan Zhang
Saifei Xu
Qiao Jin
Jianing Luo
Ce Gao
Sakthidasan Jayaprakash
Huanan Wang
Lenan Zhuang
Jin He

Frontiers in Genetics

doi 10.3389/fgene.2022.1059682

1,901 views