Original Research

Published on 18 Sep 2024

Identification of novel targets associated with cholesterol metabolism in nonalcoholic fatty liver disease: a comprehensive study using Mendelian randomization combined with transcriptome analysis

in Computational Genomics

Juan Chen
Huajing Rao
Xiaoling Zheng

Frontiers in Genetics

doi 10.3389/fgene.2024.1464865

1,319 views

Original Research

Published on 18 Sep 2024

Integrative multi-omics summary-based mendelian randomization identifies key oxidative stress-related genes as therapeutic targets for atrial fibrillation and flutter

in Computational Genomics

Shijian Chen
Junlong Sun
Wen Wen
Zhenfeng Chen
Ziheng Yu

Frontiers in Genetics

doi 10.3389/fgene.2024.1447872

1,253 views

Original Research

Published on 16 Sep 2024

Graph neural pre-training based drug-target affinity prediction

in Computational Genomics

Qing Ye
Yaxin Sun

Frontiers in Genetics

doi 10.3389/fgene.2024.1452339

538 views

Review

Published on 13 Sep 2024

Transcriptional bursting dynamics in gene expression

in Computational Genomics

Qiuyu Zhang
Wenjie Cao
Jiaqi Wang
Yihao Yin
Rui Sun
Zunyi Tian
Yuhan Hu
Yalan Tan
Ben-gong Zhang

Frontiers in Genetics

doi 10.3389/fgene.2024.1451461

1,066 views

Original Research

Published on 13 Sep 2024

Role of telomere dysfunction and immune infiltration in idiopathic pulmonary fibrosis: new insights from bioinformatics analysis

in Computational Genomics

Chenkun Fu
Xin Tian
Shuang Wu
Xiaojuan Chu
Yiju Cheng
Xiao Wu
Wengting Yang

Frontiers in Genetics

doi 10.3389/fgene.2024.1447296

1,024 views

Original Research

Published on 04 Sep 2024

Identification and validation of diagnostic genes associated with neutrophil extracellular traps of type 2 diabetes mellitus

in Computational Genomics

Meifang He
Jin Niu
Haihua Cheng
Chaoying Guo

Frontiers in Genetics

doi 10.3389/fgene.2024.1373807

1,116 views

Review

Published on 03 Sep 2024

A comprehensive review of artificial intelligence for pharmacology research

in Computational Genomics

Bing Li
Kan Tan
Angelyn R. Lao
Haiying Wang
Huiru Zheng
Le Zhang

Frontiers in Genetics

doi 10.3389/fgene.2024.1450529

1,392 views

Original Research

Published on 22 Aug 2024

A high-precision genome size estimator based on the k-mer histogram correction

in Computational Genomics

Xiangyu Liao
Wufei Zhu
Chaoyun Liu

Frontiers in Genetics

doi 10.3389/fgene.2024.1451730

700 views

Original Research

Published on 21 Aug 2024

Identification of TIMP1-induced dysregulation of epithelial-mesenchymal transition as a key pathway in inflammatory bowel disease and small intestinal neuroendocrine tumors shared pathogenesis

in Computational Genomics

Minh Tuan Tran

Frontiers in Genetics

doi 10.3389/fgene.2024.1376123

1,808 views

Methods

Published on 15 Aug 2024

SAFE-MIL: a statistically interpretable framework for screening potential targeted therapy patients based on risk estimation

in Computational Genomics

Yanfang Guan
Zhengfa Xue
Jiayin Wang
Xinghao Ai
Rongrong Chen
Xin Yi
Shun Lu
Yuqian Liu

Frontiers in Genetics

doi 10.3389/fgene.2024.1381851

729 views

Original Research

Published on 12 Aug 2024

Prognostic value of four immune-related genes in lower-grade gliomas: a biomarker discovery study

in Computational Genomics

Shuowen Wang
Zijun Wang
Zhuo Liu
Jianxin Wu

Frontiers in Genetics

doi 10.3389/fgene.2024.1403587

970 views

Original Research

Published on 09 Aug 2024

TF-EPI: an interpretable enhancer-promoter interaction detection method based on Transformer

in Computational Genomics

Bowen Liu
Weihang Zhang
Xin Zeng
Martin Loza
Sung-Joon Park
Kenta Nakai

Frontiers in Genetics

doi 10.3389/fgene.2024.1444459

1,284 views

Original Research

Published on 08 Aug 2024

Integrative analysis reveals novel insights into juvenile idiopathic arthritis pathogenesis and shared molecular pathways with associated traits

in Computational Genomics

N. Pudjihartono
D. Ho
J. M. O’Sullivan

Frontiers in Genetics

doi 10.3389/fgene.2024.1448363

1,883 views

Original Research

Published on 02 Aug 2024

MSFN: a multi-omics stacked fusion network for breast cancer survival prediction

in Computational Genomics

Ge Zhang
Chenwei Ma
Chaokun Yan
Huimin Luo
Jianlin Wang
Wenjuan Liang
Junwei Luo

Frontiers in Genetics

doi 10.3389/fgene.2024.1378809

933 views

Original Research

Published on 30 Jul 2024

Exploring the molecular landscape of osteosarcoma through PTTG family genes using a detailed multi-level methodology

in Computational Genomics

Yulin Lu
Danjun Wang
Guoao Chen
Zitong Shan
Dongmei Li

Frontiers in Genetics

doi 10.3389/fgene.2024.1431668

889 views

Original Research

Published on 29 Jul 2024

The identification and expression analysis of walnut Acyl-ACP thioesterases

in Computational Genomics

Hui Wang
Jianqing Shi
Wanhui Guo
Xiaohui Sun
Shuhui Niu
Li Chen
Shenghong Liu
Lei Ma

Frontiers in Genetics

doi 10.3389/fgene.2024.1409159

731 views

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Articles

Identification of novel targets associated with cholesterol metabolism in nonalcoholic fatty liver disease: a comprehensive study using Mendelian randomization combined with transcriptome analysis

Integrative multi-omics summary-based mendelian randomization identifies key oxidative stress-related genes as therapeutic targets for atrial fibrillation and flutter

Graph neural pre-training based drug-target affinity prediction

Transcriptional bursting dynamics in gene expression

Role of telomere dysfunction and immune infiltration in idiopathic pulmonary fibrosis: new insights from bioinformatics analysis

Identification and validation of diagnostic genes associated with neutrophil extracellular traps of type 2 diabetes mellitus

A comprehensive review of artificial intelligence for pharmacology research

A high-precision genome size estimator based on the k-mer histogram correction

Identification of TIMP1-induced dysregulation of epithelial-mesenchymal transition as a key pathway in inflammatory bowel disease and small intestinal neuroendocrine tumors shared pathogenesis

SAFE-MIL: a statistically interpretable framework for screening potential targeted therapy patients based on risk estimation

Prognostic value of four immune-related genes in lower-grade gliomas: a biomarker discovery study

TF-EPI: an interpretable enhancer-promoter interaction detection method based on Transformer

Integrative analysis reveals novel insights into juvenile idiopathic arthritis pathogenesis and shared molecular pathways with associated traits

MSFN: a multi-omics stacked fusion network for breast cancer survival prediction

Exploring the molecular landscape of osteosarcoma through PTTG family genes using a detailed multi-level methodology

The identification and expression analysis of walnut Acyl-ACP thioesterases