Frontiers in Genetics | Computational Genomics

Original Research

Published on 12 Mar 2025

Identification and validation of key biomarkers associated with immune and oxidative stress for preeclampsia by WGCNA and machine learning

in Computational Genomics

Tiantian Yu
Guiying Wang
Xia Xu
Jianying Yan

Frontiers in Genetics

doi 10.3389/fgene.2025.1500061

1,001 views

Editorial

Published on 05 Mar 2025

Editorial: The role of genes and network pharmacology in new drug discovery

in Computational Genomics

Jingxin Mao

Frontiers in Genetics

doi 10.3389/fgene.2025.1578094

539 views

Methods

Published on 03 Mar 2025

STsisal: a reference-free deconvolution pipeline for spatial transcriptomics data

in Computational Genomics

Yinghao Fu
Leqi Tian
Weiwei Zhang

Frontiers in Genetics

doi 10.3389/fgene.2025.1512435

604 views

Original Research

Published on 24 Feb 2025

Exploring the underlying molecular connections: a bioinformatics approach to link melanoma and Parkinson’s disease

in Computational Genomics

Limei Zhang
Dailin Li
Xu Zheng
Moli Wu
Qijun Yao
Haoran Chen
Zhiqiang Ye
Bo Yuan

Frontiers in Genetics

doi 10.3389/fgene.2025.1526018

997 views

Editorial

Published on 21 Feb 2025

Editorial: Integrative genetics and multi-omics of complex human disorders

in Computational Genomics

Hongsheng Gui
Christopher J. Lessard
Jinhui Liu
Miaoxin Li
Indra Adrianto

Frontiers in Genetics

doi 10.3389/fgene.2025.1574431

666 views

Original Research

Published on 21 Feb 2025

Comprehensive analysis of non-coding RNA-mediated endothelial cell-specific regulatory circuits in coronary artery disease risk

in Computational Genomics

Boshui Huang
Zhijie Lai
Xiaoyu Wang
Qinhao Zhang
Tingting Hu
Fulong Yu
Shuxian Zhou
Yan Zhang
Juan Meng

Frontiers in Genetics

doi 10.3389/fgene.2025.1559798

681 views

Original Research

Published on 20 Feb 2025

EDN1 and NTF3 in keloid pathogenesis: computational and experimental evidence as novel diagnostic biomarkers for fibrosis and inflammation

in Computational Genomics

Hui Gong
Jing Liu
Nanji Chen
Hengguang Zhao
Bailin He
Hongpei Zhang
Wenping Wang
Yi Tian

Frontiers in Genetics

doi 10.3389/fgene.2025.1516451

879 views

Methods

Published on 17 Feb 2025

WCSGNet: a graph neural network approach using weighted cell-specific networks for cell-type annotation in scRNA-seq

in Computational Genomics

Yi-Ran Wang
Pu-Feng Du

Frontiers in Genetics

doi 10.3389/fgene.2025.1553352

881 views

Original Research

Published on 11 Feb 2025

Dual graph-embedded fusion network for predicting potential microbe-disease associations with sequence learning

in Computational Genomics

Junlong Wu
Liqi Xiao
Liu Fan
Lei Wang
Xianyou Zhu

Frontiers in Genetics

doi 10.3389/fgene.2025.1511521

592 views

Data Report

Published on 10 Feb 2025

Exploring the taxonomical and functional profiles of marine microorganisms in Submarine Groundwater Discharge vent water from Mabini, Batangas, Philippines through metagenome-assembled genomes

in Computational Genomics

Joshua T. Veluz
Laurence Anthony N. Mallari
Paul Christian T. Gloria
Maria Auxilia T. Siringan

Frontiers in Genetics

doi 10.3389/fgene.2025.1522253

1,198 views

Original Research

Published on 06 Feb 2025

Exploring the relationship between sepsis and Golgi apparatus dysfunction: bioinformatics insights and diagnostic marker discovery

in Computational Genomics

Wanli Ma
Xinyi Liu
Ran Yu
Jiannan Song
Lina Hou
Ying Guo
Hongwei Wu
Dandan Feng
Qi Zhou
Haibo Li

Frontiers in Genetics

doi 10.3389/fgene.2025.1483493

922 views

Editorial

Published on 05 Feb 2025

Editorial: Towards the embedding of artificial intelligence into synthetic organisms: engineering intelligence in microorganisms

in Computational Genomics

Martín Eduardo Gutiérrez
Rafael Lahoz-Beltrá
Alberto J. Donayre-Torres

Frontiers in Genetics

doi 10.3389/fgene.2025.1562092

774 views

Original Research

Published on 04 Feb 2025

A structural genomics approach to investigate Dystrophin mutations and their impact on the molecular pathways of Duchenne muscular dystrophy

in Computational Genomics

Abdelbaset Mohamed Elasbali
Farah Anjum
Osama A. AlKhamees
Waleed Abu Al-Soud
Mohd Adnan
Anas Shamsi
Md. Imtaiyaz Hassan

Frontiers in Genetics

doi 10.3389/fgene.2025.1517707

1,302 views

Original Research

Published on 29 Jan 2025

Identifying health risk determinants and molecular targets in patients with idiopathic pulmonary fibrosis via combined differential and weighted gene co-expression analysis

in Computational Genomics

Abu Tayab Moin
Md. Asad Ullah
Jannatul Ferdous Nipa
Mohammad Sheikh Farider Rahman
Afsana Emran
Md. Minhazul Islam
Swapnil Das
Tawsif Al Arian
Mohammad Mahfuz Enam Elahi
Mukta Akter

Frontiers in Genetics

doi 10.3389/fgene.2024.1496462

1,668 views

Original Research

Published on 29 Jan 2025

Quadratic descriptors and reduction methods in a two-layered model for compound inference

in Computational Genomics

Jianshen Zhu
Naveed Ahmed Azam
Shengjuan Cao
Ryota Ido
Kazuya Haraguchi
Liang Zhao
Hiroshi Nagamochi
Tatsuya Akutsu

Frontiers in Genetics

doi 10.3389/fgene.2024.1483490

559 views

Original Research

Published on 29 Jan 2025

Antimicrobial resistance in diverse urban microbiomes: uncovering patterns and predictive markers

in Computational Genomics

Rodolfo Brizola Toscan
Wojciech Lesiński
Piotr Stomma
Balakrishnan Subramanian
Paweł P. Łabaj
Witold R. Rudnicki

Frontiers in Genetics

doi 10.3389/fgene.2025.1460508

1,125 views