Frontiers in Genetics | Computational Genomics

Original Research

Published on 21 Mar 2025

Cancer classification in high dimensional microarray gene expressions by feature selection using eagle prey optimization

in Computational Genomics

Swetha Dhamercherla
Damodar Reddy Edla
Suresh Dara

Frontiers in Genetics

doi 10.3389/fgene.2025.1528810

385 views

Original Research

Published on 20 Mar 2025

MDNN-DTA: a multimodal deep neural network for drug-target affinity prediction

in Computational Genomics

Xu Gao
Mengfan Yan
Chengwei Zhang
Gang Wu
Jiandong Shang
Congxiang Zhang
Kecheng Yang

Frontiers in Genetics

doi 10.3389/fgene.2025.1527300

524 views

Original Research

Published on 19 Mar 2025

Identification of key genes in periodontitis

in Computational Genomics

Xianyang Cheng
Shan Shen

Frontiers in Genetics

doi 10.3389/fgene.2025.1579848

465 views

Original Research

Published on 19 Mar 2025

Mechanism of action and experimental validation of key genes common to diabetic retinopathy and coronary heart disease based on multiple bioinformatics investigations

in Computational Genomics

Fanli Jiang
Shi Yin
Xinjin Zhang

Frontiers in Genetics

doi 10.3389/fgene.2025.1548147

418 views

Original Research

Published on 17 Mar 2025

Exploring the oncogenic role and prognostic value of CKS1B in human lung adenocarcinoma and squamous cell carcinoma

in Computational Genomics

Md. Solayman Hossain
Tariqul Islam Tusar
Nairita Ahsan Faruqui
Tanjim Ishraq Rahaman
Yasin Arafath Sharker
Shimran Saharia Santo
Abu Tayab Moin
Yusha Araf
Ibrahim Khalil Afif
Shoaib Saikat

Frontiers in Genetics

doi 10.3389/fgene.2025.1449466

736 views

Technology and Code

Published on 17 Mar 2025

weIMPUTE: a user-friendly web-based genotype imputation platform

in Computational Genomics

Mingliang Li
Zhuo Li
Defu Liu
Qi Li
Xiaodong Hu
Jun Yu
Jian Lin
Chunguang Bi
Guanshi Ye
Helong Yu

Frontiers in Genetics

doi 10.3389/fgene.2025.1532464

420 views

Original Research

Published on 12 Mar 2025

CLMT: graph contrastive learning model for microbe-drug associations prediction with transformer

in Computational Genomics

Liqi Xiao
Junlong Wu
Liu Fan
Lei Wang
Xianyou Zhu

Frontiers in Genetics

doi 10.3389/fgene.2025.1535279

413 views

Original Research

Published on 12 Mar 2025

Identification and validation of key biomarkers associated with immune and oxidative stress for preeclampsia by WGCNA and machine learning

in Computational Genomics

Tiantian Yu
Guiying Wang
Xia Xu
Jianying Yan

Frontiers in Genetics

doi 10.3389/fgene.2025.1500061

818 views

Editorial

Published on 05 Mar 2025

Editorial: The role of genes and network pharmacology in new drug discovery

in Computational Genomics

Jingxin Mao

Frontiers in Genetics

doi 10.3389/fgene.2025.1578094

467 views

Methods

Published on 03 Mar 2025

STsisal: a reference-free deconvolution pipeline for spatial transcriptomics data

in Computational Genomics

Yinghao Fu
Leqi Tian
Weiwei Zhang

Frontiers in Genetics

doi 10.3389/fgene.2025.1512435

551 views

Original Research

Published on 24 Feb 2025

Exploring the underlying molecular connections: a bioinformatics approach to link melanoma and Parkinson’s disease

in Computational Genomics

Limei Zhang
Dailin Li
Xu Zheng
Moli Wu
Qijun Yao
Haoran Chen
Zhiqiang Ye
Bo Yuan

Frontiers in Genetics

doi 10.3389/fgene.2025.1526018

916 views

Editorial

Published on 21 Feb 2025

Editorial: Integrative genetics and multi-omics of complex human disorders

in Computational Genomics

Hongsheng Gui
Christopher J. Lessard
Jinhui Liu
Miaoxin Li
Indra Adrianto

Frontiers in Genetics

doi 10.3389/fgene.2025.1574431

633 views

Original Research

Published on 21 Feb 2025

Comprehensive analysis of non-coding RNA-mediated endothelial cell-specific regulatory circuits in coronary artery disease risk

in Computational Genomics

Boshui Huang
Zhijie Lai
Xiaoyu Wang
Qinhao Zhang
Tingting Hu
Fulong Yu
Shuxian Zhou
Yan Zhang
Juan Meng

Frontiers in Genetics

doi 10.3389/fgene.2025.1559798

641 views

Original Research

Published on 20 Feb 2025

EDN1 and NTF3 in keloid pathogenesis: computational and experimental evidence as novel diagnostic biomarkers for fibrosis and inflammation

in Computational Genomics

Hui Gong
Jing Liu
Nanji Chen
Hengguang Zhao
Bailin He
Hongpei Zhang
Wenping Wang
Yi Tian

Frontiers in Genetics

doi 10.3389/fgene.2025.1516451

804 views

Methods

Published on 17 Feb 2025

WCSGNet: a graph neural network approach using weighted cell-specific networks for cell-type annotation in scRNA-seq

in Computational Genomics

Yi-Ran Wang
Pu-Feng Du

Frontiers in Genetics

doi 10.3389/fgene.2025.1553352

828 views

Original Research

Published on 11 Feb 2025

Dual graph-embedded fusion network for predicting potential microbe-disease associations with sequence learning

in Computational Genomics

Junlong Wu
Liqi Xiao
Liu Fan
Lei Wang
Xianyou Zhu

Frontiers in Genetics

doi 10.3389/fgene.2025.1511521

555 views