Frontiers in Genetics | Computational Genomics

Original Research

Accepted on 16 Apr 2025

Impact of Nonsynonymous Single Nucleotide Polymorphisms in PROCR Gene on Protein Stability and Thrombotic Risk: A Molecular Dynamic Approach

in Computational Genomics

Hytham A. Abuagla
Khalid Mohamed Adam
Mohamed E. Elnageeb
Elsadig Mohamed Ahmed
Elshazali W. Ali
Ali M. Edris
Abubakr Ali Elamin MohamedAhmed
Elmoiz Idris Eltieb
Tarig Babikir Algak Khalid
Bahaeldin K. Elamin

Frontiers in Genetics

doi 10.3389/fgene.2025.1580993

Original Research

Accepted on 16 Apr 2025

Potential common mechanisms between primary Sjögren's syndrome and Hashimoto's thyroiditis: A public databases-based study

in Computational Genomics

Yanjun Lin
Shupin Tang
Yan Lin
Rihui Wang
Yifeng Xing
Zonghe Xu
Yan Li
Qingxia Fang
Wenwei Wei
Dong Wu

Frontiers in Genetics

doi 10.3389/fgene.2025.1520332

Original Research

Accepted on 16 Apr 2025

Constructing Ancestral Recombination Graphs through Reinforcement Learning

in Computational Genomics

Mélanie Raymond
Marie-Hélène Descary
Cédric Beaulac
Fabrice Larribe

Frontiers in Genetics

doi 10.3389/fgene.2025.1569358

Original Research

Published on 16 Apr 2025

The potential crosstalk genes and molecular mechanisms between systemic lupus erythematosus and periodontitis

in Computational Genomics

Kai Zhao
Xiaolong Li
Qingmiao Zhu
Mengyu Zhu
Jinge Huang
Ting Zhao

Frontiers in Genetics

doi 10.3389/fgene.2025.1527713

166 views

Original Research

Accepted on 15 Apr 2025

The identification of a blood circular RNA signature that differentiates Chikungunya virus infection

in Computational Genomics

Xue Bai
Hanlin Yan
Guoxia Wen
Shaoxun Yuan
Wanjun Gu

Frontiers in Genetics

doi 10.3389/fgene.2025.1602177

Original Research

Published on 15 Apr 2025

Association prediction of lncRNAs and diseases using multiview graph convolution neural network

in Computational Genomics

Wei Zhang
Yifu Zeng
Xiaowen Xiang
Bihai Zhao
Sai Hu
Limiao Li
Xiaoyu Zhu
Lei Wang

Frontiers in Genetics

doi 10.3389/fgene.2025.1568270

266 views

Original Research

Accepted on 14 Apr 2025

High-Precision Lung Cancer Subtype Diagnosis on Imbalanced Exosomal Data via Exo-LCClassifier

in Computational Genomics

Siyu Zhan
Hao Yu
Shuang Liu
Ke Qin
Lu Guo

Frontiers in Genetics

doi 10.3389/fgene.2025.1583081

Original Research

Accepted on 14 Apr 2025

Shared genetic features inference among hypoxia-ischemia diseases in the presence of heterogenous omics data based on a novel risk assessment method

in Computational Genomics

Yifan Zhang
Jianfeng Liu
Qianxun Yang
Hongce Chen
Shuo Chen
Shaogang Li
Changgui Lei
Mingyan Fang
Huanhuan Liu
Xin Jin

Frontiers in Genetics

doi 10.3389/fgene.2025.1587854

Original Research

Accepted on 14 Apr 2025

Exploring WNT Pathway Dysregulation in Serrated Colorectal Cancer for Improved Diagnostic and Therapeutic Strategies

in Computational Genomics

Fengzhi Zhu
Helen Hoi Ning Yan
Yin Tong
Yueliang Zhao

Frontiers in Genetics

doi 10.3389/fgene.2025.1586867

Original Research

Published on 14 Apr 2025

Engineering novel features for diabetes complication prediction using synthetic electronic health records

in Computational Genomics

Daniel Voskergian
Burcu Bakir-Gungor
Malik Yousef

Frontiers in Genetics

doi 10.3389/fgene.2025.1451290

377 views

Original Research

Published on 14 Apr 2025

Explore potential immune-related targets of leeches in the treatment of type 2 diabetes based on network pharmacology and machine learning

in Computational Genomics

Tairan Hu
Zhaohui Fang

Frontiers in Genetics

doi 10.3389/fgene.2025.1554622

278 views

Original Research

Accepted on 10 Apr 2025

Integration of bulk RNA-seq and scRNA-seq reveals transcriptomic signatures associated with deep vein thrombosis

in Computational Genomics

Bao-Ze PAN
Ming-Jun Jiang
Liming Deng
Jie Chen
Xian-Peng Dai
Zi-Xuan Wu
Zhihe Deng
Dong-Yang Luo
Yang-Yi-Jing Wang
Dan Ning

Frontiers in Genetics

doi 10.3389/fgene.2025.1551879

107 views

Technology and Code

Published on 10 Apr 2025

Research on the optimization model of anti-breast cancer candidate drugs based on machine learning

in Computational Genomics

Zhou Dong
Hong Chen
Yuchen Yang
Hairong Hao

Frontiers in Genetics

doi 10.3389/fgene.2025.1523015

407 views

Original Research

Published on 10 Apr 2025

Liver failure diagnosis: key diagnostic biomarkers discovery and bioinformatic validation

in Computational Genomics

Quan Ye
Kai Wang
Hong Ye

Frontiers in Genetics

doi 10.3389/fgene.2025.1554116

241 views

Original Research

Published on 09 Apr 2025

A novel end-to-end learning framework for inferring lncRNA-disease associations based on convolution neural network

in Computational Genomics

Shunxian Zhou
Sisi Chen
Jinhai Le
Yangtai Xu
Lei Wang

Frontiers in Genetics

doi 10.3389/fgene.2025.1580512

262 views

Methods

Accepted on 08 Apr 2025

MSI Expresso: a software for determining MSI status and detecting MSI-related transcription events from RNA sequencing data

in Computational Genomics

Emmanuel Tubacher
Alexandre How-Kit
Mourad Sahbatou
Alex Duval
Victor RENAULT
JF Deleuze

Frontiers in Genetics

doi 10.3389/fgene.2025.1523278