Frontiers in Endocrinology | Diabetes: Molecular Mechanisms

Original Research

Published on 13 Jun 2024

Genome-wide association study and polygenic score assessment of insulin resistance

in Diabetes: Molecular Mechanisms

Usama Aliyu
Umm-Kulthum Ismail Umlai
Salman M. Toor
Asma A. Elashi
Yasser A. Al-Sarraj
Abdul Badi Abou−Samra
Karsten Suhre
Omar M. E. Albagha

Frontiers in Endocrinology

doi 10.3389/fendo.2024.1384103

2,687 views
1 citation

Review

Published on 10 Jun 2024

Loss of β-cell identity and dedifferentiation, not an irreversible process?

in Diabetes: Molecular Mechanisms

Sumit Patel
Maria S. Remedi

Frontiers in Endocrinology

doi 10.3389/fendo.2024.1414447

2,976 views
6 citations

Original Research

Published on 10 Jun 2024

Based on systematic druggable genome-wide Mendelian randomization identifies therapeutic targets for diabetes

in Diabetes: Molecular Mechanisms

Hu Li
Wei Li
Dongyang Li
Lijuan Yuan
Yucheng Xu
Pengtao Su
Liqiang Wu
Zhiqiang Zhang

Frontiers in Endocrinology

doi 10.3389/fendo.2024.1366290

3,935 views

Perspective

Published on 06 Jun 2024

Beta cell dedifferentiation in type 1 diabetes: sacrificing function for survival?

in Diabetes: Molecular Mechanisms

Kierstin L. Webster
Raghavendra G. Mirmira

Frontiers in Endocrinology

doi 10.3389/fendo.2024.1427723

2,086 views
1 citation

Original Research

Published on 05 Jun 2024

Exploring early DNA methylation alterations in type 1 diabetes: implications of glycemic control

in Diabetes: Molecular Mechanisms

Barbara Čugalj Kern
Jernej Kovač
Robert Šket
Tine Tesovnik
Barbara Jenko Bizjan
Julia Galhardo
Tadej Battelino
Nataša Bratina
Klemen Dovč

Frontiers in Endocrinology

doi 10.3389/fendo.2024.1416433

2,205 views
1 citation

Review

Published on 05 Jun 2024

Cuproptosis: potential new direction in diabetes research and treatment

in Diabetes: Molecular Mechanisms

Jiashu Qu
Yifan Wang
Qiuyue Wang

Frontiers in Endocrinology

doi 10.3389/fendo.2024.1344729

3,721 views
5 citations

Original Research

Published on 31 May 2024

Potential molecular and cellular mechanisms of the effects of cuproptosis-related genes in the cardiomyocytes of patients with diabetic heart failure: a bioinformatics analysis

in Diabetes: Molecular Mechanisms

Jinhao Chen
Xu Yang
Weiwen Li
Ying Lin
Run Lin
Xianzhen Cai
Baoxin Yan
Bin Xie
Jilin Li

Frontiers in Endocrinology

doi 10.3389/fendo.2024.1370387

3,597 views
5 citations

Review

Published on 30 May 2024

Advancements in research on the association between the biological CLOCK and type 2 diabetes

in Diabetes: Molecular Mechanisms

Hui Cheng
Dayuan Zhong
Yimei Tan
Menghe Huang
Sun Xijie
Hong Pan
Zixian Yang
Fangmei Huang
Feifan Li
Qizhi Tang

Frontiers in Endocrinology

doi 10.3389/fendo.2024.1320605

2,621 views
2 citations

Editorial

Published on 29 May 2024

Editorial: Early detection and combination therapy for diabetic peripheral neuropathy: what does the future look like?

in Diabetes: Molecular Mechanisms

Mark Yorek

Frontiers in Endocrinology

doi 10.3389/fendo.2024.1422734

972 views

Original Research

Published on 24 May 2024

Comprehensive machine learning models for predicting therapeutic targets in type 2 diabetes utilizing molecular and biochemical features in rats

in Diabetes: Molecular Mechanisms

Marwa Matboli
Hiba S. Al-Amodi
Abdelrahman Khaled
Radwa Khaled
Marian M. S. Roushdy
Marwa Ali
Gouda Ibrahim Diab
Mahmoud Fawzy Elnagar
Rasha A. Elmansy
Hagir H. TAhmed

Frontiers in Endocrinology

doi 10.3389/fendo.2024.1384984

4,635 views
2 citations

Original Research

Published on 21 May 2024

Unraveling the nexus of NAD+ metabolism and diabetic kidney disease: insights from murine models and human data

in Diabetes: Molecular Mechanisms

Sisi Yang
Weiyuan Gong
Yujia Wang
Chuanming Hao
Yi Guan

Frontiers in Endocrinology

doi 10.3389/fendo.2024.1384953

1,978 views
1 citation

Editorial

Published on 17 May 2024

Editorial: Islet cell development, heterogeneity and regeneration

in Diabetes: Molecular Mechanisms

Ansarullah
Adriana Migliorini
Mostafa Bakhti

Frontiers in Endocrinology

doi 10.3389/fendo.2024.1404839

1,432 views

Review

Published on 15 May 2024

Combination therapy is it in the future for successfully treating peripheral diabetic neuropathy?

in Diabetes: Molecular Mechanisms

Mark Yorek

Frontiers in Endocrinology

doi 10.3389/fendo.2024.1357859

2,793 views
1 citation

Review

Published on 10 May 2024

Autoimmune CD8+ T cells in type 1 diabetes: from single-cell RNA sequencing to T-cell receptor redirection

in Diabetes: Molecular Mechanisms

Kangping Yang
Yihan Zhang
Jiatong Ding
Zelin Li
Hejin Zhang
Fang Zou

Frontiers in Endocrinology

doi 10.3389/fendo.2024.1377322

6,363 views
7 citations

Original Research

Published on 01 May 2024

Causal relationships between blood metabolites and diabetic retinopathy: a two-sample Mendelian randomization study

in Diabetes: Molecular Mechanisms

Chongchao Yang
Yan Ma
Mudi Yao
Qin Jiang
Jinsong Xue

Frontiers in Endocrinology

doi 10.3389/fendo.2024.1383035

3,048 views
2 citations

Original Research

Published on 30 Apr 2024

GLP-1 receptor agonist improves metabolic disease in a pre-clinical model of lipodystrophy

in Diabetes: Molecular Mechanisms

Ahlima Roumane
George D. Mcilroy
Nadine Sommer
Weiping Han
Lora K. Heisler
Justin J. Rochford

Frontiers in Endocrinology

doi 10.3389/fendo.2024.1379228

2,835 views
6 citations