Mini Review

Published on 26 May 2022

Overcoming Market Failures in Pandemic Drug Discovery Through Open Science: A Canadian Solution

in In silico Methods and Artificial Intelligence for Drug Discovery

E. Richard Gold
Aled M. Edwards

Frontiers in Drug Discovery

doi 10.3389/fddsv.2022.898654

6,465 views
4 citations

Review

Published on 10 May 2022

Peptide-Based Strategies Against SARS-CoV-2 Attack: An Updated In Silico Perspective

in In silico Methods and Artificial Intelligence for Drug Discovery

G. Moroy
P. Tuffery

Frontiers in Drug Discovery

doi 10.3389/fddsv.2022.899477

4,790 views
11 citations

Mini Review

Published on 10 May 2022

Furin and COVID-19: Structure, Function and Chemoinformatic Analysis of Representative Active Site Inhibitors

in In silico Methods and Artificial Intelligence for Drug Discovery

Bruno O. Villoutreix
Iker Badiola
Abdel-Majid Khatib

Frontiers in Drug Discovery

doi 10.3389/fddsv.2022.899239

6,228 views
15 citations

Review

Published on 02 May 2022

Advances in Modelling COVID-19 in Animals

in Anti-Infective Agents

Petr Nickl
Miles Joseph Raishbrook
Linn Amanda Syding
Radislav Sedlacek

Frontiers in Drug Discovery

doi 10.3389/fddsv.2022.899587

8,901 views

Review

Published on 25 Apr 2022

Developing Small-Molecule Inhibitors of Protein-Protein Interactions Involved in Viral Entry as Potential Antivirals for COVID-19

in Anti-Infective Agents

Peter Buchwald

Frontiers in Drug Discovery

doi 10.3389/fddsv.2022.898035

4,448 views
8 citations

Mini Review

Published on 13 Apr 2022

COVID-19 Therapies: Protease Inhibitions and Novel Degrader Strategies

in Anti-Infective Agents

Michèle Reboud-Ravaux
Chahrazade El Amri

Frontiers in Drug Discovery

doi 10.3389/fddsv.2022.892057

2,797 views
3 citations

Review

Published on 30 Mar 2022

The Need for Speed and Efficiency: A Brief Review of Small Molecule Antivirals for COVID-19

in Anti-Infective Agents

Ana C. Puhl
Thomas R. Lane
Fabio Urbina
Sean Ekins

Frontiers in Drug Discovery

doi 10.3389/fddsv.2022.837587

6,323 views
9 citations

Review

Published on 22 Mar 2022

Review of Clinical Trials of COVID-19 Vaccination Booster in SARS-CoV-2 Variants Era: To Take It or Not To Take It

in Anti-Infective Agents

Michael Zhipeng Yan
Ming Yang
Ching-Lung Lai

Frontiers in Drug Discovery

doi 10.3389/fddsv.2022.858006

62,988 views
4 citations

Mini Review

Published on 10 Mar 2022

A Mini-Review of the Anticancer Properties of Cryptotanshinone: A Quinoid Diterpene Extracted From the Root of Salvia miotiorrhiza Bunge

in Anti-Cancer Drugs

Mahdyieh Naziri
Arezoo Ghafari
Hoda Mehrabi
Elham Ramezannezhad
Farzaneh Nazari
Arina Ansari
Farhad Nikzad
Niloofar Deravi

Frontiers in Drug Discovery

doi 10.3389/fddsv.2022.815017

2,654 views
4 citations

Perspective

Published on 07 Feb 2022

Deep Machine Learning for Computer-Aided Drug Design

in In silico Methods and Artificial Intelligence for Drug Discovery

Jürgen Bajorath

Frontiers in Drug Discovery

doi 10.3389/fddsv.2022.829043

7,306 views
16 citations

Review

Published on 25 Jan 2022

Is Covid-19 Severity Associated With ACE2 Degradation?

in In silico Methods and Artificial Intelligence for Drug Discovery

Ugo Bastolla
Patrick Chambers
David Abia
Maria-Laura Garcia-Bermejo
Manuel Fresno

Frontiers in Drug Discovery

doi 10.3389/fddsv.2021.789710

9,838 views
31 citations

Original Research

Published on 14 Jan 2022

Design and Synthesis of Brain Penetrant Glycopeptide Analogues of PACAP With Neuroprotective Potential for Traumatic Brain Injury and Parkinsonism

in Neurological Drugs

Christopher R. Apostol
Kelsey Bernard
Parthasaradhireddy Tanguturi
Gabriella Molnar
Mitchell J. Bartlett
Lajos Szabò
Chenxi Liu
J. Bryce Ortiz
Maha Saber
Katherine R. Giordano

Frontiers in Drug Discovery

doi 10.3389/fddsv.2021.818003

5,692 views
11 citations

Review

Published on 11 Nov 2021

Harnessing the Potential of Human Pluripotent Stem Cell-Derived Motor Neurons for Drug Discovery in Amyotrophic Lateral Sclerosis: From the Clinic to the Laboratory and Back to the Patient

in Neurological Drugs

Nuno Jorge Lamas
Laurent Roybon

Frontiers in Drug Discovery

doi 10.3389/fddsv.2021.773424

5,269 views
12 citations

Original Research

Published on 27 Oct 2021

Deep Learning Prediction of Adverse Drug Reactions in Drug Discovery Using Open TG–GATEs and FAERS Databases

in In silico Methods and Artificial Intelligence for Drug Discovery

Attayeb Mohsen
Lokesh P. Tripathi
Kenji Mizuguchi

Frontiers in Drug Discovery

doi 10.3389/fddsv.2021.768792

11,305 views
25 citations

Field Grand Challenge

Published on 28 Jul 2021

Post-Pandemic Drug Discovery and Development: Facing Present and Future Challenges

Bruno O. Villoutreix

Frontiers in Drug Discovery

doi 10.3389/fddsv.2021.728469

11,361 views
11 citations

Specialty Grand Challenge

Published on 28 Jul 2021

Grand Challenges of Computer-Aided Drug Design: The Road Ahead

in In silico Methods and Artificial Intelligence for Drug Discovery

José L. Medina-Franco

Frontiers in Drug Discovery

doi 10.3389/fddsv.2021.728551

15,288 views
33 citations

Navigation group

Articles

Overcoming Market Failures in Pandemic Drug Discovery Through Open Science: A Canadian Solution

Peptide-Based Strategies Against SARS-CoV-2 Attack: An Updated In Silico Perspective

Furin and COVID-19: Structure, Function and Chemoinformatic Analysis of Representative Active Site Inhibitors

Advances in Modelling COVID-19 in Animals

Developing Small-Molecule Inhibitors of Protein-Protein Interactions Involved in Viral Entry as Potential Antivirals for COVID-19

COVID-19 Therapies: Protease Inhibitions and Novel Degrader Strategies

The Need for Speed and Efficiency: A Brief Review of Small Molecule Antivirals for COVID-19

Review of Clinical Trials of COVID-19 Vaccination Booster in SARS-CoV-2 Variants Era: To Take It or Not To Take It

A Mini-Review of the Anticancer Properties of Cryptotanshinone: A Quinoid Diterpene Extracted From the Root of Salvia miotiorrhiza Bunge

Deep Machine Learning for Computer-Aided Drug Design

Is Covid-19 Severity Associated With ACE2 Degradation?

Design and Synthesis of Brain Penetrant Glycopeptide Analogues of PACAP With Neuroprotective Potential for Traumatic Brain Injury and Parkinsonism

Harnessing the Potential of Human Pluripotent Stem Cell-Derived Motor Neurons for Drug Discovery in Amyotrophic Lateral Sclerosis: From the Clinic to the Laboratory and Back to the Patient

Deep Learning Prediction of Adverse Drug Reactions in Drug Discovery Using Open TG–GATEs and FAERS Databases

Post-Pandemic Drug Discovery and Development: Facing Present and Future Challenges

Grand Challenges of Computer-Aided Drug Design: The Road Ahead