Frontiers in Drug Discovery

Mini Review

Published on 11 Aug 2022

Modeling heart failure with preserved ejection fraction in rodents: Where do we stand?

in Cardiovascular and Hematologic Drugs

Chun Chou
Michael T. Chin

Frontiers in Drug Discovery

doi 10.3389/fddsv.2022.948407

3,447 views
1 citation

Brief Research Report

Published on 10 Aug 2022

Stemness inhibition by (+)-JQ1 in canine and human mammary cancer cells revealed by machine learning

in Anti-Cancer Drugs

Maycon Marção
Susanne Müller
Pedro Luiz P. Xavier
Tathiane M. Malta

Frontiers in Drug Discovery

doi 10.3389/fddsv.2022.953988

3,187 views
2 citations

Mini Review

Published on 18 Jul 2022

Nanobodies: COVID-19 and Future Perspectives

in Anti-Infective Agents

Guillermo Valenzuela-Nieto
Zaray Miranda-Chacon
Constanza Salinas-Rebolledo
Ronald Jara
Alexei Cuevas
Anne Berking
Alejandro Rojas-Fernandez

Frontiers in Drug Discovery

doi 10.3389/fddsv.2022.927164

8,785 views
13 citations

Clinical Trial

Published on 15 Jul 2022

Reszinate—A Phase 1/2 Randomized Clinical Trial of Zinc and Resveratrol Utilizing Home Patient-Obtained Nasal and Saliva Viral Sampling

in Anti-Infective Agents

Henry G. Kaplan
Kai Wang
Kimberly M. Reeves
James M. Scanlan
Christopher C. Nunn
Douglas A. Kieper
Joshua L. Mark
Inyoul Lee
Rachel Liu
Ruyun Jin

Frontiers in Drug Discovery

doi 10.3389/fddsv.2022.910124

4,715 views
1 citation

Brief Research Report

Published on 08 Jul 2022

The Prospects of Monte Carlo Antibody Loop Modelling on a Fault-Tolerant Quantum Computer

in In silico Methods and Artificial Intelligence for Drug Discovery

Jonathan Allcock
Anna Vangone
Agnes Meyder
Stanislaw Adaszewski
Martin Strahm
Chang-Yu Hsieh
Shengyu Zhang

Frontiers in Drug Discovery

doi 10.3389/fddsv.2022.908870

3,715 views
8 citations

Perspective

Published on 30 May 2022

Addressing Antibiotic Failure—Beyond Genetically Encoded Antimicrobial Resistance

in Anti-Infective Agents

Evan F. Haney
Robert E. W. Hancock

Frontiers in Drug Discovery

doi 10.3389/fddsv.2022.892975

7,406 views
15 citations

Mini Review

Published on 26 May 2022

Overcoming Market Failures in Pandemic Drug Discovery Through Open Science: A Canadian Solution

in In silico Methods and Artificial Intelligence for Drug Discovery

E. Richard Gold
Aled M. Edwards

Frontiers in Drug Discovery

doi 10.3389/fddsv.2022.898654

7,010 views
5 citations

Review

Published on 10 May 2022

Peptide-Based Strategies Against SARS-CoV-2 Attack: An Updated In Silico Perspective

in In silico Methods and Artificial Intelligence for Drug Discovery

G. Moroy
P. Tuffery

Frontiers in Drug Discovery

doi 10.3389/fddsv.2022.899477

5,146 views
12 citations

Mini Review

Published on 10 May 2022

Furin and COVID-19: Structure, Function and Chemoinformatic Analysis of Representative Active Site Inhibitors

in In silico Methods and Artificial Intelligence for Drug Discovery

Bruno O. Villoutreix
Iker Badiola
Abdel-Majid Khatib

Frontiers in Drug Discovery

doi 10.3389/fddsv.2022.899239

6,796 views
19 citations

Review

Published on 02 May 2022

Advances in Modelling COVID-19 in Animals

in Anti-Infective Agents

Petr Nickl
Miles Joseph Raishbrook
Linn Amanda Syding
Radislav Sedlacek

Frontiers in Drug Discovery

doi 10.3389/fddsv.2022.899587

9,677 views
1 citation

Review

Published on 25 Apr 2022

Developing Small-Molecule Inhibitors of Protein-Protein Interactions Involved in Viral Entry as Potential Antivirals for COVID-19

in Anti-Infective Agents

Peter Buchwald

Frontiers in Drug Discovery

doi 10.3389/fddsv.2022.898035

5,099 views
12 citations

Mini Review

Published on 13 Apr 2022

COVID-19 Therapies: Protease Inhibitions and Novel Degrader Strategies

in Anti-Infective Agents

Michèle Reboud-Ravaux
Chahrazade El Amri

Frontiers in Drug Discovery

doi 10.3389/fddsv.2022.892057

3,006 views
3 citations

Review

Published on 30 Mar 2022

The Need for Speed and Efficiency: A Brief Review of Small Molecule Antivirals for COVID-19

in Anti-Infective Agents

Ana C. Puhl
Thomas R. Lane
Fabio Urbina
Sean Ekins

Frontiers in Drug Discovery

doi 10.3389/fddsv.2022.837587

7,157 views
10 citations

Review

Published on 22 Mar 2022

Review of Clinical Trials of COVID-19 Vaccination Booster in SARS-CoV-2 Variants Era: To Take It or Not To Take It

in Anti-Infective Agents

Michael Zhipeng Yan
Ming Yang
Ching-Lung Lai

Frontiers in Drug Discovery

doi 10.3389/fddsv.2022.858006

64,747 views
4 citations

Mini Review

Published on 10 Mar 2022

A Mini-Review of the Anticancer Properties of Cryptotanshinone: A Quinoid Diterpene Extracted From the Root of Salvia miotiorrhiza Bunge

in Anti-Cancer Drugs

Mahdyieh Naziri
Arezoo Ghafari
Hoda Mehrabi
Elham Ramezannezhad
Farzaneh Nazari
Arina Ansari
Farhad Nikzad
Niloofar Deravi

Frontiers in Drug Discovery

doi 10.3389/fddsv.2022.815017

2,993 views
4 citations

Perspective

Published on 07 Feb 2022

Deep Machine Learning for Computer-Aided Drug Design

in In silico Methods and Artificial Intelligence for Drug Discovery

Jürgen Bajorath

Frontiers in Drug Discovery

doi 10.3389/fddsv.2022.829043

7,790 views
23 citations