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Original Research

Published on 26 Jun 2018

Probing Substituents in the 1- and 3-Position: Tetrahydropyrazino-Annelated Water-Soluble Xanthine Derivatives as Multi-Target Drugs With Potent Adenosine Receptor Antagonistic Activity

in Medicinal and Pharmaceutical Chemistry

  • Pierre Koch
  • Andreas Brunschweiger
  • Vigneshwaran Namasivayam
  • Stefan Ullrich
  • Annalisa Maruca
  • Beatrice Lazzaretto
  • Petra Küppers
  • Sonja Hinz
  • Jörg Hockemeyer
  • Michael Wiese
Probing Substituents in the 1- and 3-Position: Tetrahydropyrazino-Annelated Water-Soluble Xanthine Derivatives as Multi-Target Drugs With Potent Adenosine Receptor Antagonistic Activity
Frontiers in Chemistry
doi 10.3389/fchem.2018.00206
  • 4,005 views
  • 10 citations