Original Research

Published on 15 Oct 2024

Sustainable synthesis of silver nanoparticles from Azadirachta indica: antimicrobial, antioxidant and in silico analysis for periodontal treatment

in Medicinal and Pharmaceutical Chemistry

Binapani Barik
Bhabani Sankar Satapathy
Gurudutta Pattnaik
Desai Vijay Bhavrao
Krishna Prasad Shetty

Frontiers in Chemistry

doi 10.3389/fchem.2024.1489253

488 views

Original Research

Published on 08 Oct 2024

Computational exploration of acefylline derivatives as MAO-B inhibitors for Parkinson’s disease: insights from molecular docking, DFT, ADMET, and molecular dynamics approaches

in Medicinal and Pharmaceutical Chemistry

Ali Irfan
Ameer Fawad Zahoor
Yassir Boulaamane
Sadia Javed
Huma Hameed
Amal Maurady
Muhammed Tilahun Muhammed
Sajjad Ahmad
Aamal A. Al-Mutairi
Irum Shahzadi

Frontiers in Chemistry

doi 10.3389/fchem.2024.1449165

809 views

Original Research

Published on 08 Oct 2024

Stretching the structural envelope of imatinib to reduce β-amyloid production by modulating both β- and γ-secretase cleavages of APP

in Medicinal and Pharmaceutical Chemistry

William J. Netzer
Anjana Sinha
Mondana Ghias
Emily Chang
Katherina Gindinova
Emily Mui
Ji-Seon Seo
Subhash C. Sinha

Frontiers in Chemistry

doi 10.3389/fchem.2024.1381205

380 views

Original Research

Published on 03 Oct 2024

Stemona alkaloid derivative induce ferroptosis of colorectal cancer cell by mediating carnitine palmitoyltransferase 1

in Medicinal and Pharmaceutical Chemistry

He Yang
Ling Wang
Mengcheng Zhang
Xingkang Wu
Zhenyu Li
Kaiqing Ma

Frontiers in Chemistry

doi 10.3389/fchem.2024.1478674

547 views

Review

Published on 26 Sep 2024

Venom-derived peptides for breaking through the glass ceiling of drug development

in Medicinal and Pharmaceutical Chemistry

Lou Freuville
Chloé Matthys
Loïc Quinton
Jean-Pierre Gillet

Frontiers in Chemistry

doi 10.3389/fchem.2024.1465459

1,152 views

Original Research

Published on 24 Sep 2024

Topological indices based VIKOR assisted multi-criteria decision technique for lung disorders

in Medicinal and Pharmaceutical Chemistry

Tahreem Ashraf
Nazeran Idrees

Frontiers in Chemistry

doi 10.3389/fchem.2024.1407911

408 views

Original Research

Published on 20 Sep 2024

Structure-based virtual screening towards the discovery of novel thrombin inhibitors with Anti-HCC activities

in Medicinal and Pharmaceutical Chemistry

Xiaoxi Zhang
Xumei Zheng
Chun Han
Lintao Wu

Frontiers in Chemistry

doi 10.3389/fchem.2024.1451574

422 views

Editorial

Published on 19 Sep 2024

Editorial: Advances in wound repair and regeneration: novel materials, targets and applications

in Medicinal and Pharmaceutical Chemistry

Xinwei Cheng
Jia Zhou

Frontiers in Chemistry

doi 10.3389/fchem.2024.1487091

292 views

Editorial

Published on 17 Sep 2024

Editorial: Novel compounds from chemistry to druggable candidates

in Medicinal and Pharmaceutical Chemistry

Pete Rose
Jawad Nasim
Yi-Zhun Zhu

Frontiers in Chemistry

doi 10.3389/fchem.2024.1494407

291 views

Original Research

Published on 13 Sep 2024

Phytochemical analysis, identification of bioactive compounds using GC-MS, in vitro and in silico hypoglycemic potential, in vitro antioxidant potential, and in silico ADME analysis of Chlorophytum comosum root and leaf

in Medicinal and Pharmaceutical Chemistry

P. Kavya
R. C. Theijeswini
M. Gayathri

Frontiers in Chemistry

doi 10.3389/fchem.2024.1458505

860 views

Original Research

Published on 13 Sep 2024

Phytochemical profile, physicochemical, antioxidant and antimicrobial properties of Juniperus phoenicea and Tetraclinis articulate: in vitro and in silico approaches

in Medicinal and Pharmaceutical Chemistry

Ayoub Asbabou
Touijer Hanane
Aman Allah Gourich
Farhan Siddique
Aziz Drioiche
Firdaous Remok
Soukaina Saidi
Imad Adadi
Hamid Khamar
Khalid S. Almaary

Frontiers in Chemistry

doi 10.3389/fchem.2024.1397961

1,064 views

Original Research

Published on 10 Sep 2024

Salsoline derivatives, genistein, semisynthetic derivative of kojic acid, and naringenin as inhibitors of A42R profilin-like protein of monkeypox virus: in silico studies

in Medicinal and Pharmaceutical Chemistry

Mohamed Chebaibi
Mohammed Bourhia
Fatima ez-zahra Amrati
Meryem Slighoua
Ibrahim Mssillou
Mourad A. M. Aboul-Soud
Asaad Khalid
Rym Hassani
Dalila Bousta
Sanae Achour

Frontiers in Chemistry

doi 10.3389/fchem.2024.1445606

839 views

Original Research

Published on 06 Sep 2024

Design and synthesis new indole-based aromatase/iNOS inhibitors with apoptotic antiproliferative activity

in Medicinal and Pharmaceutical Chemistry

Lamya H. Al-Wahaibi
Hesham A. Abou-Zied
Mostafa H. Abdelrahman
Martha M. Morcoss
Laurent Trembleau
Bahaa G. M. Youssif
Stefan Bräse

Frontiers in Chemistry

doi 10.3389/fchem.2024.1432920

531 views

Original Research

Published on 30 Aug 2024

Design and synthesis of new 1,2,4-oxadiazole/quinazoline-4-one hybrids with antiproliferative activity as multitargeted inhibitors

in Medicinal and Pharmaceutical Chemistry

Amira M. Mohamed
Ola M. F. Abou-Ghadir
Yaser A. Mostafa
Kholood A. Dahlous
Stefan Bräse
Bahaa G. M. Youssif

Frontiers in Chemistry

doi 10.3389/fchem.2024.1447618

787 views

Original Research

Published on 21 Aug 2024

Molecular insights into kaempferol derivatives as potential inhibitors for CDK2 in colon cancer: pharmacophore modeling, docking, and dynamic analysis

in Medicinal and Pharmaceutical Chemistry

Fei Xing
Zhicheng Wang
Noor Bahadar
Can Wang
Xu-Dong Wang

Frontiers in Chemistry

doi 10.3389/fchem.2024.1440196

986 views
2 citations

Original Research

Published on 16 Aug 2024

Bactericidal, anti-hemolytic, and anticancerous activities of phytofabricated silver nanoparticles of glycine max seeds

in Medicinal and Pharmaceutical Chemistry

K. B. Vijendra Kumar
Kavitha Raj Varadaraju
Prasanna D. Shivaramu
C. M. Hemanth Kumar
H. R. Prakruthi
B. M. Chandra Shekara
Bhargav Shreevatsa
Tanveer A. Wani
K. C. Prakasha
Shiva Prasad Kollur

Frontiers in Chemistry

doi 10.3389/fchem.2024.1427797

1,099 views

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Articles

Sustainable synthesis of silver nanoparticles from Azadirachta indica: antimicrobial, antioxidant and in silico analysis for periodontal treatment

Computational exploration of acefylline derivatives as MAO-B inhibitors for Parkinson’s disease: insights from molecular docking, DFT, ADMET, and molecular dynamics approaches

Stretching the structural envelope of imatinib to reduce β-amyloid production by modulating both β- and γ-secretase cleavages of APP

Stemona alkaloid derivative induce ferroptosis of colorectal cancer cell by mediating carnitine palmitoyltransferase 1

Venom-derived peptides for breaking through the glass ceiling of drug development

Topological indices based VIKOR assisted multi-criteria decision technique for lung disorders

Structure-based virtual screening towards the discovery of novel thrombin inhibitors with Anti-HCC activities

Editorial: Advances in wound repair and regeneration: novel materials, targets and applications

Editorial: Novel compounds from chemistry to druggable candidates

Phytochemical analysis, identification of bioactive compounds using GC-MS, in vitro and in silico hypoglycemic potential, in vitro antioxidant potential, and in silico ADME analysis of Chlorophytum comosum root and leaf

Phytochemical profile, physicochemical, antioxidant and antimicrobial properties of Juniperus phoenicea and Tetraclinis articulate: in vitro and in silico approaches

Salsoline derivatives, genistein, semisynthetic derivative of kojic acid, and naringenin as inhibitors of A42R profilin-like protein of monkeypox virus: in silico studies

Design and synthesis new indole-based aromatase/iNOS inhibitors with apoptotic antiproliferative activity

Design and synthesis of new 1,2,4-oxadiazole/quinazoline-4-one hybrids with antiproliferative activity as multitargeted inhibitors

Molecular insights into kaempferol derivatives as potential inhibitors for CDK2 in colon cancer: pharmacophore modeling, docking, and dynamic analysis

Bactericidal, anti-hemolytic, and anticancerous activities of phytofabricated silver nanoparticles of glycine max seeds