Mini Review

Published on 17 Oct 2023

Bacterial outer membrane vesicles as drug delivery carrier for photodynamic anticancer therapy

in Medicinal and Pharmaceutical Chemistry

Yuan Jiang
ZunZhen Zhou
Chongzhi Liu
Limei Wang
Chun Li

Frontiers in Chemistry

doi 10.3389/fchem.2023.1284292

2,606 views
3 citations

Original Research

Published on 12 Oct 2023

Radiochemical and biological assessments of a PSMA-I&S cold kit for fast and inexpensive 99mTc-labeling for SPECT imaging and radioguided surgery in prostate cancer

in Medicinal and Pharmaceutical Chemistry

Leonardo Lima Fuscaldi
Danielle Vieira Sobral
Ana Claudia Ranucci Durante
Fernanda Ferreira Mendonça
Ana Cláudia Camargo Miranda
Carla Salgueiro
Silvia Gomez de Castiglia
Lilian Yuri Itaya Yamaga
Marcelo Livorsi da Cunha
Luciana Malavolta

Frontiers in Chemistry

doi 10.3389/fchem.2023.1271176

3,003 views
5 citations

Original Research

Published on 11 Oct 2023

In silico and in vitro study of bioactive compounds of Nigella sativa for targeting neuropilins in breast cancer

in Medicinal and Pharmaceutical Chemistry

Imran Zafar
Arfa Safder
Hassan Imran Afridi
Sania Riaz
Rizwan -ur-Rehman
Ahsanullah Unar
Fakhar Un Nisa
Abdel-Rhman Z. Gaafar
Mohammed Bourhia
Gezahign Fentahun Wondmie

Frontiers in Chemistry

doi 10.3389/fchem.2023.1273149

5,059 views
1 citation

Original Research

Published on 06 Oct 2023

Pharmacological activities of chemically characterized essential oils from Haplophyllum tuberculatum (Forssk.)

in Medicinal and Pharmaceutical Chemistry

Abdelkrim Agour
Ibrahim Mssillou
Aimad Allali
Mohamed Chebaibi
Youness El Abdali
Azeddin El Barnossi
Yousef A. Bin Jardan
Gezahign Fentahun Wondmie
Hiba-Allah Nafidi
Mohammed Bourhia

Frontiers in Chemistry

doi 10.3389/fchem.2023.1251449

4,735 views
2 citations

Original Research

Published on 06 Oct 2023

A gene expression profile-based approach to screen the occurrence and predisposed host characteristics of drug-induced liver injury: a case study of Psoralea corylifolia Linn

in Medicinal and Pharmaceutical Chemistry

Ming-Liang Zhang
Wei-Xia Li
Xiao-Yan Wang
Hui Zhang
Ya-Li Wu
Liu-Qing Yang
Xiao-Fei Chen
Shu-Qi Zhang
Yu-Long Chen
Ke-Ran Feng

Frontiers in Chemistry

doi 10.3389/fchem.2023.1259569

2,437 views

Original Research

Published on 26 Sep 2023

Exploration of phenolic acid derivatives as inhibitors of SARS-CoV-2 main protease and receptor binding domain: potential candidates for anti-SARS-CoV-2 therapy

in Medicinal and Pharmaceutical Chemistry

Nusrat Shafiq
Aiman Mehroze
Warda Sarwar
Uzma Arshad
Shagufta Parveen
Maryam Rashid
Ariba Farooq
Naila Rafiq
Gezahign Fentahun Wondmie
Yousef A. Bin Jardan

Frontiers in Chemistry

doi 10.3389/fchem.2023.1251529

3,289 views
2 citations

Original Research

Published on 06 Sep 2023

Synthesis, in-vitro inhibition of cyclooxygenases and in silico studies of new isoxazole derivatives

in Medicinal and Pharmaceutical Chemistry

Waqas Alam
Haroon Khan
Muhammad Saeed Jan
Umer Rashid
Ali Abusharha
Maria Daglia

Frontiers in Chemistry

doi 10.3389/fchem.2023.1222047

2,668 views
8 citations

Original Research

Published on 05 Sep 2023

Green synthesis of Piper nigrum copper-based nanoparticles: in silico study and ADMET analysis to assess their antioxidant, antibacterial, and cytotoxic effects

in Medicinal and Pharmaceutical Chemistry

Modumudi Kiranmayee
Nambi Rajesh
M. Vidya Vani
Habeeb Khadri
Arifullah Mohammed
Suresh V. Chinni
Gobinath Ramachawolran
Khateef Riazunnisa
Ashaimaa Y. Moussa

Frontiers in Chemistry

doi 10.3389/fchem.2023.1218588

4,218 views
14 citations

Original Research

Published on 29 Aug 2023

Deciphering the binding mechanism of an anti-cancer phytochemical plumbagin with calf thymus DNA using biophysical and in silico techniques

in Medicinal and Pharmaceutical Chemistry

Abdul Rahaman
Farah Anjum
Aknita Kumari
Alaa Shafie
Mahafooj Alee
Omnia Badr
Shaheer Hasan Khan
Amal Adnan Ashour
Ali Hazazi
Sultan Arif

Frontiers in Chemistry

doi 10.3389/fchem.2023.1248458

2,233 views
1 citation

Review

Published on 22 Aug 2023

Halimanes and cancer: ent-halimic acid as a starting material for the synthesis of antitumor drugs

in Medicinal and Pharmaceutical Chemistry

Alejandro M. Roncero
Ignacio E. Tobal
Rosalina F. Moro
David Diez
Isidro S. Marcos

Frontiers in Chemistry

doi 10.3389/fchem.2023.1225355

2,137 views

Original Research

Published on 17 Aug 2023

Insight into biological activities of chemically characterized extract from Marrubium vulgare L. in vitro, in vivo and in silico approaches

in Medicinal and Pharmaceutical Chemistry

Aman Allah Gourich
Hanane Touijer
Aziz Drioiche
Ayoub Asbabou
Firdaous Remok
Soukaina Saidi
Farhan Siddique
Atika Ailli
Mohammed Bourhia
Ahmad Mohammad Salamatullah

Frontiers in Chemistry

doi 10.3389/fchem.2023.1238346

3,085 views
4 citations

Mini Review

Published on 10 Aug 2023

1,2,3-Triazoles and their metal chelates with antimicrobial activity

in Medicinal and Pharmaceutical Chemistry

Lozan Todorov
Irena Kostova

Frontiers in Chemistry

doi 10.3389/fchem.2023.1247805

3,203 views
10 citations

Original Research

Published on 09 Aug 2023

Investigation of bacterial neuraminidase inhibition of xanthones bearing geranyl and prenyl groups from Cratoxylum cochinchinense

in Medicinal and Pharmaceutical Chemistry

Jeong Yoon Kim
Zuo Peng Li
Gihwan Lee
Jeong Ho Kim
Abdul Bari Shah
Yong Hyun Lee
Ki Hun Park

Frontiers in Chemistry

doi 10.3389/fchem.2023.1245071

1,624 views

Original Research

Published on 07 Aug 2023

Molecular characterization and in silico evaluation of surfactins produced by endophytic bacteria from Phanera splendens

in Medicinal and Pharmaceutical Chemistry

Eleane Monaliza de Cerqueira de Souza
Maycon Vinicius Damasceno de Oliveira
José Edson de Sousa Siqueira
Daniela Cristiane da Cruz Rocha
Anderson do Nonato Rosario Marinho
Andrey Moacir do Rosario Marinho
Patrícia Santana Barbosa Marinho
Anderson H. Lima

Frontiers in Chemistry

doi 10.3389/fchem.2023.1240704

2,243 views

Original Research

Published on 04 Aug 2023

Unveiling the antitumor potential of novel N-(substituted-phenyl)-8-methoxycoumarin-3-carboxamides as dual inhibitors of VEGFR2 kinase and cytochrome P450 for targeted treatment of hepatocellular carcinoma

in Medicinal and Pharmaceutical Chemistry

Eman M. Radwan
Eman Abo-Elabass
Atef E. Abd El-Baky
Hussah Abdullah Alshwyeh
Riyad A. Almaimani
Ghassan Almaimani
Ibrahim Abdel Aziz Ibrahim
Abdulaziz Albogami
Mariusz Jaremko
Samar Z. Alshawwa

Frontiers in Chemistry

doi 10.3389/fchem.2023.1231030

2,846 views
7 citations

Original Research

Published on 03 Aug 2023

Exploring the potential of propanamide-sulfonamide based drug conjugates as dual inhibitors of urease and cyclooxygenase-2: biological and their in silico studies

in Medicinal and Pharmaceutical Chemistry

Saghir Ahmad
Muhammad Abdul Qadir
Mahmood Ahmed
Muhammad Imran
Numan Yousaf
Tanveer A. Wani
Seema Zargar
Ijaz Ali
Muhammad Muddassar

Frontiers in Chemistry

doi 10.3389/fchem.2023.1206380

1,990 views
4 citations

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Articles

Bacterial outer membrane vesicles as drug delivery carrier for photodynamic anticancer therapy

Radiochemical and biological assessments of a PSMA-I&S cold kit for fast and inexpensive 99mTc-labeling for SPECT imaging and radioguided surgery in prostate cancer

In silico and in vitro study of bioactive compounds of Nigella sativa for targeting neuropilins in breast cancer

Pharmacological activities of chemically characterized essential oils from Haplophyllum tuberculatum (Forssk.)

A gene expression profile-based approach to screen the occurrence and predisposed host characteristics of drug-induced liver injury: a case study of Psoralea corylifolia Linn

Exploration of phenolic acid derivatives as inhibitors of SARS-CoV-2 main protease and receptor binding domain: potential candidates for anti-SARS-CoV-2 therapy

Synthesis, in-vitro inhibition of cyclooxygenases and in silico studies of new isoxazole derivatives

Green synthesis of Piper nigrum copper-based nanoparticles: in silico study and ADMET analysis to assess their antioxidant, antibacterial, and cytotoxic effects

Deciphering the binding mechanism of an anti-cancer phytochemical plumbagin with calf thymus DNA using biophysical and in silico techniques

Halimanes and cancer: ent-halimic acid as a starting material for the synthesis of antitumor drugs

Insight into biological activities of chemically characterized extract from Marrubium vulgare L. in vitro, in vivo and in silico approaches

1,2,3-Triazoles and their metal chelates with antimicrobial activity

Investigation of bacterial neuraminidase inhibition of xanthones bearing geranyl and prenyl groups from Cratoxylum cochinchinense

Molecular characterization and in silico evaluation of surfactins produced by endophytic bacteria from Phanera splendens

Unveiling the antitumor potential of novel N-(substituted-phenyl)-8-methoxycoumarin-3-carboxamides as dual inhibitors of VEGFR2 kinase and cytochrome P450 for targeted treatment of hepatocellular carcinoma

Exploring the potential of propanamide-sulfonamide based drug conjugates as dual inhibitors of urease and cyclooxygenase-2: biological and their in silico studies