Editorial

Accepted on 15 Nov 2024

Editorial: Antibacterial effects and mode of action of new active substances against drug resistant pathogenic bacteria

in Medicinal and Pharmaceutical Chemistry

Abderrahmen Merghni

Frontiers in Chemistry

doi 10.3389/fchem.2024.1526451

Original Research

Published on 15 Nov 2024

UPLC-ESI/MSn metabolic profiling of Cedrela odorata L. and Toona ciliata M. Roem and in vitro investigation of their anti-diabetic activity supported with molecular docking studies

in Medicinal and Pharmaceutical Chemistry

Heba A. S. El-Nashar
Ayman M. Al-Qaaneh
Md. Shimul Bhuia
Raihan Chowdhury
Mostafa A. Abdel-Maksoud
Hossam Ebaid
Abdul Malik
Muhammad Torequl Islam
Mohammed Aufy
Esraa A. Elhawary

Frontiers in Chemistry

doi 10.3389/fchem.2024.1462309

Original Research

Published on 15 Nov 2024

Development of photoactive biomaterial using modified fullerene nanoparticles

in Medicinal and Pharmaceutical Chemistry

Gabrielė Saulėnienė
Monika Kirsnyte-Snioke
Arūnas Stirkė
Vitalija Jasulaitiene
Antanas Straksys
Samuelis Dobilaitis
Wanessa C. M. A. Melo

Frontiers in Chemistry

doi 10.3389/fchem.2024.1432624

Original Research

Accepted on 13 Nov 2024

The study of halogen effect on the reactivity of the serine-targeting covalent warheads

in Medicinal and Pharmaceutical Chemistry

Conghao Gai
Ya Zhang
Shihao Zhang
Xueyan Hu
Xiaoyun Chai
Yan Zou
Guang-Bo Ge
Qingjie Zhao

Frontiers in Chemistry

doi 10.3389/fchem.2024.1504453

Original Research

Published on 12 Nov 2024

Synthesis, enzyme inhibition, and docking studies of new schiff bases of disalicylic acid methylene-based derivatives as dual-target antibacterial agents

in Medicinal and Pharmaceutical Chemistry

Lamya H. Al-Wahaibi
Mohamed A. Mahmoud
Hayat Ali Alzahrani
Hesham A. Abou-Zied
Alshaimaa Abdelmoez
Bahaa G. M. Youssif
Stefan Bräse
Safwat M. Rabea

Frontiers in Chemistry

doi 10.3389/fchem.2024.1493906

145 views

Original Research

Accepted on 11 Nov 2024

Composition and antimicrobial activity of hydroalcoholic extracts of Pleurotus eryngii var. ferulae and P. eryngii var. elaeoselini

in Medicinal and Pharmaceutical Chemistry

Flavio Polito
Laura De Martino
Giulia Mirabile
Giuseppe Venturella
Maria Letizia Gargano
Vincenzo De Feo
Hazem Elshafie
Ippolito Camele

Frontiers in Chemistry

doi 10.3389/fchem.2024.1498787

Original Research

Accepted on 08 Nov 2024

Antioxidant potential, antimicrobial activity, polyphenol profile analysis, and cytotoxicity against breast cancer cell lines of hydroethanolic extracts of leaves of (Ficus carica L.) from Eastern Morocco

in Medicinal and Pharmaceutical Chemistry

Aziz Tikent
Salah LAARAJ
Toufik Bouddine
Mohamed Chebaibi
Mohamed Bouhrim
ELFAZAZI Kaoutar
Ali Alqahtani
Omar M. Noman
Lhoussain Hajji
Larbi Rhazi

Frontiers in Chemistry

doi 10.3389/fchem.2024.1505473

Original Research

Published on 06 Nov 2024

New series of 4,6-diaryl pyrimidines: facile synthesis and antiproliferative activity as dual EGFR/VEGFR-2 inhibitors

in Medicinal and Pharmaceutical Chemistry

Yaser A. Mostafa
Jalil Abdeljalil Assoud
Ahmed Y. Desoky
Samy Mohamady
Nesma M. Mohamed
Ola I. A. Salem
Zainab M. Almarhoon
Stefan Bräse
Bahaa G. M. Youssif

Frontiers in Chemistry

doi 10.3389/fchem.2024.1498104

301 views

Editorial

Published on 06 Nov 2024

Editorial: Hot topic: anti-inflammatory drug discovery

in Medicinal and Pharmaceutical Chemistry

Abdul Ajees Abdul Salam
Tejas M. Dhameliya
Ahmed Mahal
Sajad Moradi
Paolo Coghi

Frontiers in Chemistry

doi 10.3389/fchem.2024.1512607

228 views

Original Research

Published on 31 Oct 2024

Aspidosperma nitidum reduces parasite load and modulates cytokines in BALB/c mice infected with Leishmania (Leishmania) amazonensis

in Medicinal and Pharmaceutical Chemistry

Heliton Patrick Cordovil Brígido
Everton Luiz Pompeu Varela
Antônio Rafael Quadros Gomes
Jorddy Neves Cruz
Juliana Correa-Barbosa
José Edson de Sousa Siqueira
Cristian Kallahan Silva Chagas
Andrey Moacir do Rosário Marinho
Liliane Almeida Carneiro
Márlia Regina Coelho-Ferreira

Frontiers in Chemistry

doi 10.3389/fchem.2024.1492770

283 views

Original Research

Published on 30 Oct 2024

Exploring the mechanism of tetramethylpyrazine in the treatment of osteoarthritis based on network pharmacology

in Medicinal and Pharmaceutical Chemistry

Juncen Li
Daiying Song
Bohui Li
Yajie Wang
Huilin Sun
Qinglin Li
Xiangming Lin
Di Wang
Guangdong Zhou
Yu Liu

Frontiers in Chemistry

doi 10.3389/fchem.2024.1415390

197 views

Original Research

Published on 24 Oct 2024

Antioxidant, Anti-Alzheimer’s, anticancer, and cytotoxic properties of peanut oil: in vitro, in silico, and GC-MS analysis

in Medicinal and Pharmaceutical Chemistry

Hanène Djeghim
Djamila Benouchenne
El Hassen Mokrani
Huda Alsaeedi
David Cornu
Mikhael Bechelany
Ahmed Barhoum

Frontiers in Chemistry

doi 10.3389/fchem.2024.1487084

3,805 views

Original Research

Published on 23 Oct 2024

Synthesis of new triazole derivatives and their potential applications for removal of heavy metals from aqueous solution and antibacterial activities

in Medicinal and Pharmaceutical Chemistry

Chunyun Xu
Na Yang
Haichun Yu
Xiaojing Wang

Frontiers in Chemistry

doi 10.3389/fchem.2024.1473097

433 views

Original Research

Published on 21 Oct 2024

Development of novel CDK9 and CYP3A4 inhibitors for cancer therapy through field and computational approaches

in Medicinal and Pharmaceutical Chemistry

Aisha A. Alsfouk
Abdelmoujoud Faris
Ivana Cacciatore
Radwan Alnajjar

Frontiers in Chemistry

doi 10.3389/fchem.2024.1473398

652 views

Original Research

Accepted on 16 Oct 2024

Exploring the antimicrobial potential of lactobacilli against early-stage and mature biofilms of Staphylococcus aureus and Pseudomonas aeruginosa

in Medicinal and Pharmaceutical Chemistry

NIHARIKA SINGH
Rohini Devidas Gulhane
Maitri Goel
Pudke Payal Udelal
Anamika Singh
Vikas Sangwan
Manvesh Kumar Sihag
Gunjan Goel
Harsh Panwar
Anil Kumar Puniya

Frontiers in Chemistry

doi 10.3389/fchem.2024.1425666

Original Research

Published on 16 Oct 2024

Synthesis and antibacterial potential of novel thymol derivatives against methicillin-resistant Staphylococcus aureus and P. aeruginosa pathogenic bacteria

in Medicinal and Pharmaceutical Chemistry

Ashutosh Shahi
Rakshit Manhas
Srija Bhattacharya
Arti Rathore
Puneet Kumar
Jayanta Samanta
Manish Kumar Sharma
Avisek Mahapa
Prasoon Gupta
Jasha Momo H. Anal

Frontiers in Chemistry

doi 10.3389/fchem.2024.1482852

610 views

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Articles

Editorial: Antibacterial effects and mode of action of new active substances against drug resistant pathogenic bacteria

UPLC-ESI/MSn metabolic profiling of Cedrela odorata L. and Toona ciliata M. Roem and in vitro investigation of their anti-diabetic activity supported with molecular docking studies

Development of photoactive biomaterial using modified fullerene nanoparticles

The study of halogen effect on the reactivity of the serine-targeting covalent warheads

Synthesis, enzyme inhibition, and docking studies of new schiff bases of disalicylic acid methylene-based derivatives as dual-target antibacterial agents

Composition and antimicrobial activity of hydroalcoholic extracts of Pleurotus eryngii var. ferulae and P. eryngii var. elaeoselini

Antioxidant potential, antimicrobial activity, polyphenol profile analysis, and cytotoxicity against breast cancer cell lines of hydroethanolic extracts of leaves of (Ficus carica L.) from Eastern Morocco

New series of 4,6-diaryl pyrimidines: facile synthesis and antiproliferative activity as dual EGFR/VEGFR-2 inhibitors

Editorial: Hot topic: anti-inflammatory drug discovery

Aspidosperma nitidum reduces parasite load and modulates cytokines in BALB/c mice infected with Leishmania (Leishmania) amazonensis

Exploring the mechanism of tetramethylpyrazine in the treatment of osteoarthritis based on network pharmacology

Antioxidant, Anti-Alzheimer’s, anticancer, and cytotoxic properties of peanut oil: in vitro, in silico, and GC-MS analysis

Synthesis of new triazole derivatives and their potential applications for removal of heavy metals from aqueous solution and antibacterial activities

Development of novel CDK9 and CYP3A4 inhibitors for cancer therapy through field and computational approaches

Exploring the antimicrobial potential of lactobacilli against early-stage and mature biofilms of Staphylococcus aureus and Pseudomonas aeruginosa

Synthesis and antibacterial potential of novel thymol derivatives against methicillin-resistant Staphylococcus aureus and P. aeruginosa pathogenic bacteria