Frontiers in Chemistry | Chemical Biology

Original Research

Published on 04 Oct 2019

Systematic Dual Targeting of Dendritic Cell C-Type Lectin Receptor DC-SIGN and TLR7 Using a Trifunctional Mannosylated Antigen

in Chemical Biology

Rui-Jun Eveline Li
Tim P. Hogervorst
Silvia Achilli
Sven C. Bruijns
Tim Arnoldus
Corinne Vivès
Chung C. Wong
Michel Thépaut
Nico J. Meeuwenoord
Hans van den Elst

Frontiers in Chemistry

doi 10.3389/fchem.2019.00650

10,670 views
45 citations

Original Research

Published on 02 Oct 2019

Heteroglycoclusters With Dual Nanomolar Affinities for the Lectins LecA and LecB From Pseudomonas aeruginosa

in Chemical Biology

David Goyard
Baptiste Thomas
Emilie Gillon
Anne Imberty
Olivier Renaudet

Frontiers in Chemistry

doi 10.3389/fchem.2019.00666

3,142 views
19 citations

Original Research

Published on 29 Aug 2019

Comprehensive Landscape of Active Deubiquitinating Enzymes Profiled by Advanced Chemoproteomics

in Chemical Biology

Adán Pinto-Fernández
Simon Davis
Abigail B. Schofield
Hannah C. Scott
Ping Zhang
Eidarus Salah
Sebastian Mathea
Philip D. Charles
Andreas Damianou
Gareth Bond

Frontiers in Chemistry

doi 10.3389/fchem.2019.00592

22,945 views
51 citations

Original Research

Published on 28 Aug 2019

A Highly Selective NIR Fluorescent Turn-on Probe for Hydroxyl Radical and Its Application in Living Cell Images

in Chemical Biology

Xingyu Qu
Wenting Song
Zhen Shen

Frontiers in Chemistry

doi 10.3389/fchem.2019.00598

4,884 views
22 citations

Mini Review

Published on 09 Aug 2019

Recognition of Proteins by Metal Chelation-Based Fluorescent Probes in Cells

in Chemical Biology

Nan Jiang
Hongyan Li
Hongzhe Sun

Frontiers in Chemistry

doi 10.3389/fchem.2019.00560

6,706 views
11 citations

Original Research

Published on 25 Jul 2019

Design and Optimization of Thioglycosyl–naphthalimides as Efficient Inhibitors Against Human O-GlcNAcase

in Chemical Biology

Shengqiang Shen
Lili Dong
Wei Chen
Renjie Wu
Huizhe Lu
Qing Yang
Jianjun Zhang

Frontiers in Chemistry

doi 10.3389/fchem.2019.00533

2,319 views
3 citations

Review

Published on 02 Jul 2019

Three Decades of Amyloid Beta Synthesis: Challenges and Advances

in Chemical Biology

Johanes K. Kasim
Iman Kavianinia
Paul W. R. Harris
Margaret A. Brimble

Frontiers in Chemistry

doi 10.3389/fchem.2019.00472

11,624 views
20 citations

Original Research

Published on 14 May 2019

Near-Infrared Aggregation-Induced Emission-Active Probe Enables in situ and Long-Term Tracking of Endogenous β-Galactosidase Activity

in Chemical Biology

Wei Fu
Chenxu Yan
Yutao Zhang
Yiyu Ma
Zhiqian Guo
Wei-Hong Zhu

Frontiers in Chemistry

doi 10.3389/fchem.2019.00291

7,773 views
46 citations

Original Research

Published on 16 Apr 2019

Elucidating the Lipid Binding Properties of Membrane-Active Peptides Using Cyclised Nanodiscs

in Chemical Biology

Alan H. Zhang
Ingrid A. Edwards
Biswa P. Mishra
Gagan Sharma
Michael D. Healy
Alysha G. Elliott
Mark A. T. Blaskovich
Matthew A. Cooper
Brett M. Collins
Xinying Jia

Frontiers in Chemistry

doi 10.3389/fchem.2019.00238

7,367 views
24 citations

Original Research

Published on 02 Apr 2019

Fluoro-Aryl Substituted α,β2,3-Peptides in the Development of Foldameric Antiparallel β-Sheets: A Conformational Study

in Chemical Biology

Raffaella Bucci
Alessandro Contini
Francesca Clerici
Egle Maria Beccalli
Fernando Formaggio
Irene Maffucci
Sara Pellegrino
Maria Luisa Gelmi

Frontiers in Chemistry

doi 10.3389/fchem.2019.00192

3,338 views
16 citations

Original Research

Published on 29 Mar 2019

Rational Design of Antiangiogenic Helical Oligopeptides Targeting the Vascular Endothelial Growth Factor Receptors

in Chemical Biology

Simone Zanella
Gianfranco Bocchinfuso
Marta De Zotti
Daniela Arosio
Franca Marino
Stefano Raniolo
Luca Pignataro
Giovanni Sacco
Antonio Palleschi
Alvaro S. Siano

Frontiers in Chemistry

doi 10.3389/fchem.2019.00170

4,124 views
13 citations

Original Research

Published on 28 Mar 2019

N,N-Dimethylaminoxy Carbonyl, a Polar Protecting Group for Efficient Peptide Synthesis

in Chemical Biology

Ryo Okamoto
Emiko Ono
Masayuki Izumi
Yasuhiro Kajihara

Frontiers in Chemistry

doi 10.3389/fchem.2019.00173

7,644 views

Mini Review

Published on 27 Mar 2019

Self-Assembling Peptides as Extracellular Matrix Mimics to Influence Stem Cell's Fate

in Chemical Biology

Katharina S. Hellmund
Beate Koksch

Frontiers in Chemistry

doi 10.3389/fchem.2019.00172

9,262 views
57 citations

Original Research

Published on 26 Mar 2019

1,4-Disubstituted 1H-1,2,3-Triazole Containing Peptidotriazolamers: A New Class of Peptidomimetics With Interesting Foldamer Properties

in Chemical Biology

David C. Schröder
Oliver Kracker
Tanja Fröhr
Jerzy Góra
Michał Jewginski
Anke Nieß
Iris Antes
Rafał Latajka
Antoine Marion
Norbert Sewald

Frontiers in Chemistry

doi 10.3389/fchem.2019.00155

9,462 views
18 citations

Review

Published on 21 Mar 2019

Chemical Biology Gateways to Mapping Location, Association, and Pathway Responsivity

in Chemical Biology

Marcus J. C. Long
Xuyu Liu
Yimon Aye

Frontiers in Chemistry

doi 10.3389/fchem.2019.00125

7,117 views
9 citations

Original Research

Published on 13 Feb 2019

Probing Anti-inflammatory Properties Independent of NF-κB Through Conformational Constraint of Peptide-Based Interleukin-1 Receptor Biased Ligands

in Chemical Biology

Azade Geranurimi
Colin W. H. Cheng
Christiane Quiniou
Tang Zhu
Xin Hou
José Carlos Rivera
Daniel J. St-Cyr
Kim Beauregard
Vadim Bernard-Gauthier
Sylvain Chemtob

Frontiers in Chemistry

doi 10.3389/fchem.2019.00023

8,265 views
13 citations